Oncologia fegato tiroide pancreas milza
Tutti i libri di Oncologia fegato tiroide pancreas milza
Immunotherapy combination strategies in unresectable hepatocellular carcinoma
Lorenza Rimassa
editore: Minerva Medica
pagine: 192
Benign Tumors of the Liver
Francesco Cetta
,
Gianfranco Ferla
e altri
editore: Springer International Publishing AG
pagine: 337
Diagnosis of benign liver tumors is experiencing exponential growth, mainly owing to the diffusion of more accurate imaging techniques. This monograph examines the epidemiology, histopathology and genetics of these tumors and provides a systematic overview of their evolution and differential diagnosis. Care is taken to document surgical indications accurately, with a view to assisting in the avoidance of useless interventions. Open, laparoscopic and robotic surgical techniques are described and illustrated, emphasizing the optimization of intra- and postoperative management in order to avoid potential complications and degeneration. In these chapters, attention is drawn to the ways in which the surgical management of benign liver tumors differs from that of malignant tumors. The book concludes by examining the role of interventional radiology in patients with benign liver tumors.
Noncolorectal, Nonneuroendocrine Liver Metastases
Diagnosis and Current Therapies
Isidoro Di Carlo
editore: Springer International Publishing AG
pagine: 214
This book offers a complete overview on non colorectal non neuroendocrine (NCRNNE) liver metastases and describes in detail the currently available therapies. Each chapter focuses on the treatment of metastases from a particular primary malignancy and also provides valuable information on incidence, natural history and diagnosis. NCRNNE liver metastases are rare entities compared with colorectal and neuroendocrine metastases, for which the treatments are well codified. While more publications have appeared on the topic in recent years, an in-depth study has to date been lacking. Furthermore, most published series are insufficiently comparable as they comprise patients with NCRNNE hepatic metastases from a variety of primary malignancies and consequently overlook differences in tumor behavior, frequency of isolated hepatic metastases, response to neoadjuvant or adjuvant therapy and interval between diagnosis of the primary tumor and the liver metastases. This book, with its more specific approach, will serve not only as an up-to-date guide to diagnosis and treatment but also as a reference on which to base future studies.
Pancreatic Cystic Neoplasms
From Imaging to Differential Diagnosis and Management
George H. Sakorafas
,
Michael Sarr
e altri
editore: Springer Verlag
pagine: 74
This book provides a thorough overview of the detection of PCNs using modern imaging techniques and a clear guide to the recognition of the different subtypes of PCN based on their radiologic and histopathologic features. This volume will serve as an excellent aid to the selection of optimal therapeutic strategies based on preoperative diagnosis. A further important feature is the emphasis placed on radiologic, clinical, and surgical correlations. Pancreatic cystic neoplasms (PCNs) have been increasingly recognized during the past decade, mainly because of the widespread use of modern imaging modalities for the investigation of often unrelated abdominal symptoms. The three most common subtypes of PCN are serous cystic neoplasms, mucinous cystic neoplasms, and intraductal papillary mucinous neoplasms. These subtypes have distinct radiologic and histopathological features, and their biological behavior differs greatly.
Accurate preoperative diagnosis is of prime importance in selecting the optimal therapeutic strategy: while serous cystic neoplasms are almost always benign, and may be treated conservatively, mucinous cystic neoplasms and intraductal papillary mucinous neoplasms have malignant potential, warranting an aggressive surgical approach, i.e., pancreatectomy. Pancreatic Cystic Neoplasms will be of great interest to surgeons, gastroenterologists, radiologists, oncologists, and pathologists, and also to internists and residents in these specialties.
Management of Neuroendocrine Tumors of the Pancreas and digestive tract
From surgery to targeted therapies : A Multidisciplinary Approach
Eric Raymond
editore: Springer
pagine: 236
Biopsy Interpretation of the Liver
Michael Torbenson
editore: Lippincott Williams and Wilkins
pagine: 544
Exceptional liver disease treatment starts with Biopsy Interpretation of the Liver. A tried-and-true guide for physicians, surgeons, and clinicians, this bench reference promises to keep you informed, skilled, and on the forefront of liver biopsy. Go beyond the superficial, framing each diagnosis in its most common clinical context, alongside clinical recommendations. Don't fall behind in your understanding of biopsy; equip your practice with the tools to effectively diagnose and offer the highest in patient care. Key Features: key differential features of tumors, organized according to diagnostic category; and specific tumors accompanied by high quality photomicrographs and illustrations. Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access to: complete content with enhanced navigation; a powerful search that pulls results from content in the book, your notes, and even the web; cross-linked pages, references, and more for easy navigation; highlighting tool for easier reference of key content throughout the text; ability to take and share notes with friends and colleagues; quick reference tabbing to save your favorite content for future use; over 300 additional images; and 140 question test bank.
Clinical Dilemmas in Primary Liver Cancer
Roger Williams , Simon D. Taylor-Robinson
editore: Wiley-Blackwell (an imprint of John Wiley & Sons Ltd)
pagine: 230
Clinical Dilemmas in Liver Cancer follows the successful format of the other books in the Clinical Dilemmas series, with each chapter focused on a specific dilemma, or issue facing doctors in their day-to-day job, and providing them with practical clinical information and help to better assessment and treat their patients - in this case patients suffering from liver cancer, the third commonest cancer in terms of mortality worldwide. Chapters feature up-to-date information on the basic mechanisms, epidemiological risk factors, screening and surveillance strategies, diagnosis and treatment. It is an extremely practical and clinically-orientated book, and as most patients around the world present with advanced disease, a main focus is on the most recent advances allowing early diagnosis and use of locoregional and systemic therapy, surgery, transplantation and combination therapies. Each chapter is authored by an international expert in the relevant area.
Primary Carcinomas of the Liver
Hero Hussain , Isaac R. Francis
editore: Cambridge
pagine: 254
Primary carcinomas of the liver are increasing in incidence in the developed world, probably due to dietary and environmental factors as well as the known role of infective agents such as Hepatitis C. They are usually diagnosed in the advanced stages and carry high morbidity and mortality. This volume summarises the latest developments in imaging of primary hepatic carcinomas, emphasising the multidisciplinary approach to the care of patients. In addition to extensive chapters on the radiological issues surrounding diagnosis and staging of the malignancies, individual chapters on epidemiology, pathology, and surgical and non-surgical treatment options are included. All treatment options are considered for both HCC and cholangiocarcinoma, including newer techniques such as TACE. Only by a well orchestrated multidisciplinary team approach including epidemiologists, diagnostic radiologists, hepatologists, oncologic surgeons, radiation oncologists, and pathologists can these complex malignancies be managed successfully.
Hepatocellular Carcinoma
Diagnosis and Treatment
Brian I. Carr
editore: Humana Press Inc.
pagine: 432
Hepatocellular cancer is the fifth most common cancer, with 600,000 new cases reported each year worldwide. Additionally, exciting changes in the science of HCC in the last four years have turned the practice of diagnosing and treating the disease upside down. In Hepatocellular Carcinoma: Diagnosis and Treatment, Second Edition, the leading experts in the field of HCC thoroughly update and expand upon the critically acclaimed first edition with all the latest developments in the diagnosis and treatment of primary liver cancer. The book details for physicians the diagnostic and therapeutic decision making process for dealing with such problems as incidental tumors in the liver transplant, the role of neo-adjuvant chemotherapy, intra-arterial vs intravenous therapy, the uses of embolization, and the significance of portal vein thrombus. New chapters discuss the introduction into clinical practice of cell cycle growth inhibitors, an expanded knowledge of Genomics and Proteomics, and novel ways of delivering intra-hepatic chemotherapy. This cutting-edge text is a vital resource and must have for today's hepatologists and medical and surgical oncologists.
Interventional Radiological Treatment of Liver Tumors
Andy Adam , Peter R. Mueller
editore: Cambridge
pagine: 232
Interventional radiological techniques are becoming increasingly important in the treatment of both primary and secondary malignant liver tumours. Surgery for liver tumours can be effective but carries considerable risks and new techniques have recently been developed. This volume provides an account of interventional radiological methods by some of the greatest experts in the field. It includes chapters on cryotherapy, chemoembolization and radiofrequency ablation and an extensive chapter on imaging techniques. The scientific background of these techniques, the pathology of the diseases involved and an analysis of more traditional surgical methods are also described. This text brings together the latest advances in this fast-developing field.
Pancreatic Cancer
Jay P. Heiken
editore: Cambridge
pagine: 208
Written by a team of expert authors from all members of the multidisciplinary cancer care team, Pancreatic Cancer summarizes our current understanding of the epidemiology, genetics, imaging and treatment of these complex malignancies. Each imaging modality is reviewed, with an emphasis on MDCT, MRI and EUS; the key aspects of image interpretation are covered. Separate chapters focus on diagnosis and staging of ductal adenocarcinoma, cystic pancreatic neoplasms and neuroendocrine tumors; rare neoplasms and benign pancreatic disorders that mimic pancreatic cancer are also considered. All treatment options are discussed in detail, including surgery, chemotherapy and radiation therapy, and the multidisciplinary approach to patients with more advanced disease is fully reviewed. This volume is a state-of-the-art review of current practice and knowledge of pancreatic cancer.
Essentials of Thyroid Cancer Management
A Guidebook for Endocrinologists, Surgeons, Nuclear Medicine Physicians and Radiation Oncologists
Ernest L. Mazzaferri
,
Jessica Kirwan
e altri
editore: Springer Verlag New York Inc.
pagine: 480
The goal of this book is to provide Endocrinologists, Surgeons, Nuclear Medicine Physicians, and Radiation Oncologists with practical advice about managing patients with thyroid cancer. This book will not replace the excellent publications that focus on a highly speci?c topic or provide an exhaustive review of major s- jects from the perspective of a particular specialty. These kinds of publications will always be an important source of information for both students and expe- enced practitioners. The void that we see is the lack of a single, concise, up-- date reference that is applicable to all of the specialists who make clinical de- sions about thyroid cancer patients. Essentials of Thyroid Cancer Management will ?ll this void in a manner that is both user-friendly and technically compreh- sive. For reading ef?ciency, this book contains the minimum of text required to explain how to make sound clinical decisions in speci?c situations. We rely heavily on tables, diagrams, graphs, photographs, and other ?gures to convey this information. Subjects are addressed in a large number of chapters that each focus on a relatively narrow topic.
In some cases, there is overlap between the information in multiple different chapters so the reader does not have to page back and forth between different sections of the book. As occurs in every area of medicine, there is controversy about important issues in the management of thyroid cancer.
Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas
Molecular Genetics: Liver and Pancreatic Carcinomas
M. A. Hayat
editore: Academic Press Inc
pagine: 432
Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer. This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today. This is the only book available that translates molecular genetics into cancer diagnosis. The results of each Immunohistochemical and in situ hybridization method are presented in the form of color illustrations.
The methods discussed were either developed or refined by expert contributors in their own laboratories.
Thyroid Cancer
F. Grunwald , H. J. Biersack
editore: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
pagine: 386
"Thyroid Cancer" describes all current diagnostic techniques, including FDG-PET and MRI. In recent years, these modalities have documented hitherto hidden radioiodine-negative metastases, thus improving surgical therapy. The whole gamut of treatment, including surgery, radioiodine therapy, percutaneous radiation therapy and medical management, is covered. In some 10 per cent of differentiated thyroid cancers, the well-known treatment tools of surgery and radioiodine therapy are not sufficient. New treatment modalities such as high-dose radioiodine therapy, redifferentiation therapy with retinoic acid and recombinant TSH are therefore highlighted. In a special section devoted to medullary thyroid cancer, new imaging procedures such as octreotide scintigraphy are described. The second edition includes two new chapters, on I-124 PET and dosimetry. Other chapters have been modified particularly in view of the new UICC classification, with special regard to the definition of T1 tumors.
Pancreatic Cancer
Methods and Protocols
Gloria H. Su
editore: Humana Press Inc.
pagine: 352
Pancreatic ductal adenocarcinoma is the fourth leading cause of cancer death in the United States. Annually approximately 30,000 Americans are diagnosed with the disease and most will die from it within five years. P- creatic ductal adenocarcinoma is unique because of its late onset in age, high mortality, small tumor samples infiltrated with normal cells, and a lack of both early detection and effective therapies. Some of these characteristics have made studying this disease a challenge. Pancreatic cancer develops as a result of the accumulation of genetic alterations in cancer-causing genes, such as the oncogenes and the tumor-s- pressor genes. In the last decade, major progress has been made in identifying important oncogenes and tumor-suppressor genes for the disease. In Panc- atic Cancer: Methods and Protocols, we review the classical techniques that have contributed to the advances in pancreatic research and introduce new strategies that we hope will add to future breakthroughs in the field of cancer biology.
Pancreatic Cancer: Methods and Protocols provides a broad range of protocols for molecular, cellular, pathological, and statistical analyses of s- radic and familial pancreatic cancer. It covers topics from in vitro cell c- tures to in vivo mouse models, DNA to protein manipulation, and mutation analyses to treatment development. We believe that our book will prove an invaluable source of proven protocols for those who are interested in either basic or translational research in pancreatic cancer.
Pancreatic Cancer
Douglas B. Evans
,
James L. Abruzzese
e altri
editore: Springer Verlag New York Inc.
pagine: 444
The MD Anderson Solid Tumor Oncology series presents cutting-edge surgical treatment and medical therapy for specific sites. This volume, Pancreatic Cancer, addresses epidemiology and molecular biology, inherited syndromes, staging, surgical techniques, multimodality therapy, and emerging therapies. The individual chapters focus on narrow, specific topics to produce a reference work of value to those interested in pancreatic cancer from a clinical and translational research perspective. A must-have for surgical oncologists and general surgeons.
Hepatobiliary cancer
Atlas of clinical oncology
Blumgart, L. H. , Fong, Y. , Jarnagin, W. R.
editore: Decker
pagine: 304
Part of the ACS Atlas of Clinical Oncology series, this book offers an overview of hepatobiliary cancer. The topics covered include benign liver tumors, primary liver tumors, metastatic liver cancer, metastatic neuroendocnne tumors, surgical and non-surgical ablative techniques for liver tumors, and liver resection, including laparoscopy.
Pancreatic cancer
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Cameron, J. L.
editore: B.C.Decker
pagine: 274
Building upon a distinguished career in surgical oncology, John L. Cameron has drawn upon the expertise of contributors from the best cancer centres in the United States to compile this volume on pancreatic cancer. This volume of the ACS Series includes chapters on molecular genetics, lymph node dissection and palliation of pain.
