Nefropatologia

Designed specifically for nephrologists and trainees practicing in the ICU, Handbook of Critical Care Nephrology is a portable critical care reference with a unique and practical nephrology focus. Full-color illustrations, numerous algorithms, and intuitively arranged contents make this manual a must-have resource for nephrology in today's ICU. Covers all essential topics related to nephrology in the ICU, including ICU monitoring, drugs and blood products, imaging, acute kidney injury, electrolytes and acid-base disorders, poisonings and intoxications, extracorporeal therapies, organ transplantation, and ethics and palliative care. Provides valuable information on specific conditions including sepsis, obstetrics, abdominal compartment syndrome, AKI in burns and trauma, gastrointestinal bleeding, neurological emergencies, environmental topics such as hemorrhagic fever and terrorism, hematologic/oncologic emergencies, and more. Includes easy-to-understand visual abstracts of key studies. Enrich Your Ebook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

Primary glomerulonephritis is one of the most frequent renal diseases, and a main cause of end-stage kidney disease. Glomerulonephritis has multiple subtypes, each with different physiopathologies, clinical presentations, and management requirements, which makes treatment difficult. As a complex set of diseases, the choice of symptomatic and specific treatment is critical to ameliorating the relentless course of glomerulonephritis. Focusing on all aspects of primary glomerulonephritis, from their epidemiologies and classification, to their pathogenesis and treatment, this third edition of Treatment of Primary Glomerulonephritis has been fully updated to include the latest research and evidence-based practice. With a strong emphasis on drugs used for both symptomatic and specific treatments, mechanisms of action, effectiveness, and potential toxicity are considered for therapeutic strategies in the different subtypes of primary glomerulonephritis. Each chapter follows a clear and logical format, allowing easy access to key information. Featuring over 20 full-colour histological images of different diseases to aid diagnosis, and with commentary from internationally recognised experts in the field, this new edition is an essential resource for all practising or academic clinical nephrologists.

Revised and updated by experts in both nephrology and clinical nutrition, this seventh edition of Handbook of Nutrition and the Kidney provides practical and clinically relevant information for addressing the nutritional needs of patients with acute and chronic kidney disease. Concise yet in-depth, the book is packed with tables and charts in every chapter, and outlines detailed and daily nutritional requirements, including proteins, vitamins, minerals, lipids, other fatty acids, and more. Features:Useful for physicians, dietitians, nurses, and anyone who works with patients afflicted by chronic kidney disease (CKD), hemodialysis (HD), peritoneal dialysis (PD), and kidney transplants.Each chapter contains tables and figures that visually demonstrate nutritional principles and enable you to find essential information quickly.Presents easy-to-follow sample menus with lists of ingredients and dietary recommendations.Chapters cover the affects of kidney disease on metabolism and hormonal function, nutritional approaches to caring for different patient types, an overview of nutritional biochemistry and digestive physiology in healthy adults, and more.Includes guidelines and requirements for people with hypertension.Your book purchase includes a complimentary download of the enhanced eBook for iOS, Android, PC & Mac. Take advantage of these practical features that will improve your eBook experience:The ability to download the eBook on multiple devices at one time-providing a seamless reading experience online or offline.Powerful search tools and smart navigation cross-links that allow you to search within this book, or across your entire library of VitalSource eBooks.Multiple viewing options that enable you to scale images and text to any size without losing page clarity as well as responsive design.The ability to highlight text and add notes with one click.

For more than 40 years, this well-regarded reference has bridged the gap between basic and clinical sciences for the many disorders associated with electrolyte imbalances and kidney dysfunction. Authoritative and easy to read, the eighth edition has been thoroughly updated by experts in the field to reflect recent developments in renal pathophysiology. Each chapter first introduces normal physiology, then covers each disorder's clinical features, diagnosis, and treatment. Helpful diagrams, algorithms, and tables further explain the complex concepts. Key Features:A new two-color format throughout promotes easier comprehension and faster navigation.Redrawn and colorized line drawings make complex concepts easier to understand and more visually appealing.New coverage includes: recent developments in disorders of water homeostasis; substantial new information on genetic hypokalemic and hyperkalemic disorders; new content on calcium, phosphorus, vitamin D, and parathyroid hormone activity; a new chapter on the genomic and nongenomic effects of angiotensin and aldosterone in renal and cardiovascular disease; an up-to-date discussion of the pivotal role of the kidney in the pathogenesis of hypertensive states; new advances in our understanding of the glomerulopathies and vasculitides; and much more.Ideal for all members of the nephrology team, including residents and fellows in nephrology, internal medicine, and other specialties, as well as nurses and physician assistants.Your book purchase includes a complimentary download of the enhanced eBook for iOS, Android, PC & Mac. Take advantage of these practical features that will improve your eBook experience: The ability to download the eBook on multiple devices at one time - providing a seamless reading experience online or offlinePowerful search tools and smart navigation cross-links allow you to search within this book, or across your entire library of VitalSource eBooksMultiple viewing options offer the ability to scale images and text to any size without losing page clarity as well as responsive designThe ability to highlight text and add notes with one click.

If you're looking to deepen your understanding of kidney disease, look no further than Heptinstall's Pathology of the Kidney, 7th Edition. Authored by the world's most accomplished renal pathologists, this image-rich text conveys the intricacies and comprehensiveness of renal disease, offering powerful diagnostic and treatment recommendations from decades of clinical research. Stay up to date on the cutting edge of kidney research and treatment and offer your patients the best therapeutic options and preventative measures available today with this all-inclusive two volume set. Key Features: including over 1500 color images, diagrammatic line drawings, easy reference tables, and figures; deconstructs kidney pathology, etiology, pathogenesis, demographics, and epidemiology; clinical correlations feature presentation, outcomes, and guidance on patient management; and up to date recent studies in clinico-pathologic correlation and patient management. Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access to: complete content with enhanced navigation; a powerful search that pulls results from content in the book, your notes, and even the web; cross-linked pages, references, and more for easy navigation; highlighting tool for easier reference of key content throughout the text; ability to take and share notes with friends and colleagues; and quick reference tabbing to save your favorite content for future use.

Diabetes and Kidney Disease reviews the most up-to-date research on diabetic nephropathy, the current understanding of its pathophysiology, renal structural alterations and clinical features and summarizes recent evidence-based clinical treatment modalities for the prevention and management of diabetic kidney disease. General clinical aspects are covered, as well as an overview to the novel approaches being designed by leading researchers in the field. A convenient compendium for physicians involved in the care of diabetic patients with varying degrees of kidney involvement, Diabetes and Kidney Disease is also a handy resource for medical residents and students interested in the current status and future approaches to reducing the burden of diabetes and diabetic kidney disease.

Diabetes and the Kidney provides endocrinologists andnephrologists of all levels with expert clinical diagnosis andmanagement guidance for this extremely common diabeticcomplication.Practical and accessible, chapters contain textfeatures such as case histories, potential pitfall boxes, keypoints, management algorithms, and useful weblinks to fullyengage the reader and provide expert guidance to help cliniciansbest manage their patients. In addition, allrelevant international society guidelines and recommendationsare fully included.After an initial analysis of the epidemiology andpathogenesis of kidney complications in diabetes, it quickly moveson to the following core sections: - Special Situations, Risk factors and Complications- examining diabetic nephropathy in relation to each other diabeticcomplication, ie cardiovascular disease- Prevention and Therapy - focusing on the most up todate information regarding prevention, diagnosis, treatment, andmanagement of kidney disease in diabetes.Expertly edited, and with contributions from an experiencedinternational team, Diabetes and Kidney Disease will be theperfect tool to consult when managing diabetic patients withassociated kidney problems.

"The Washington Manual of Nephrology Subspecialty Consult" has been thoroughly updated and covers inpatient and outpatient management of nephrology with the same clinical practicality as the widely-popular "Washington Manual [trademark] of Medical Therapeutics". It has been written by the residents, fellows, and attending physicians of the distinguished Washington University School of Medicine and is tailored for residents performing inpatient consults, students working on an inpatient medicine service, and specialists seeking fast-access information on the management of common renal diseases. Organized for quick and easy access to information, this handbook includes sections on general approaches to kidney disease, electrolyte and acid-base disorders, acute kidney injury and continuous renal replacement, causes of kidney disease, pregnancy and nephrolithiasis, and chronic kidney disease. Appendices include dosing adjustments for antimicrobials and antiretrovirals and a listing of red flag drugs that may cause renal impairment. Don't miss the other key topics in "The Washington Manual [trademark Subspecialty Consult Series": Allergy, Asthma, and Immunology, Gastroenterology, Hematology and Oncology. Infectious Disease, Rheumatology. "The Washington Manual [trademark]" is a registered mark belonging to Washington University in St. Louis to which international legal protection applies. The mark is used in this publication by LWW under license from Washington University.

Expert renal pathologists have created this easy-to-use reference book featuring comprehensive coverage of common and rare renal diseases and their variants. The book includes an up-to-date, concise presentation of major pathological, clinical, pathophysiological, and genetic information for over 200 diagnoses. "Diagnostic Pathology: Kidney Diseases" is a highly anticipated title in the "Diagnostic Pathology" series published by "Amirsys". As readers have come to expect from "Amirsys", this book is filled with superior medical images, including gross pathology, a wide range of pathology stains, detailed medical illustrations, and hundreds of differential diagnoses. This disease-oriented guide, focused on medical kidney disorders, is a veritable one-stop shop for kidney disease pathology, including infections, injury, toxins, drugs, and genetics.

Progression of chronic diseases in general and chronic kidney disease in particular has been traditionally viewed in the light of various contributors to development of glomerulosclerosis and tubulointerstitial scarring culminating in renal fibrosis. Indeed, this dogma prevailed for decades underscoring experimental attempts to halt fibrotic processes. Breakthrough investigations of the past few years on stem/progenitor cell involvement in organ regeneration caused a conceptual shift in tackling the mechanisms of nephrosclerosis. It has become clear that the rate of progression of chronic kidney disease is the net sum of the opposing trends: degenerative fibrotic processes and regenerative repair mechanisms. The latter part of this equation has been by and large ignored for years and only recently attracted investigative attention. This book revisits the problem of kidney disease by focusing on regenerative mechanisms in renal repair and on the ways these regenerative processes can become subverted by an intrinsic disease process eventuating in its progression. Cutting-edge investigations are summarized by the most experienced international team of experts. This title presents a comprehensive, translational source for all aspects of renal stem cells, tissue regeneration, and stem cell therapies for renal diseases in one reference work. This will ultimately result in time savings for academic, medical and pharma researchers. Experts in the renal stem cell system in kidney repair and regeneration take readers from the bench research to new therapeutic approaches, providing a common language for nephrology researchers, fellows and other stem cell researchers. This enables the discussion of development of stem cells and their use in the repair and regeneration of the kidney.

Severe inflammation of the kidney can indicate the serious, negative prognosis of lupus nephritis when present in conjunction with systemic lupus erythematosus (SLE), a chronic autoimmune connective tissue disease that can affect any part of the body, most often harming the heart, joints, skin, lungs, blood vessels, liver, kidneys, and nervous system. This book pulls together in one comprehensive reference the current knowledge regarding the inherited and immunologic abnormalities that have been identified in SLE, with specific reference to the development of renal disease and the way in which these factors may impact upon the chronic care of these patients. Since publication of the first edition in 1999, the discipline of medicine has experienced some revolutionary changes in the way drugs are used to treat to immune system diseases. On the basis of careful analysis of physical make-up, the immune system, and microscopic features of the human body, it has become clear that multiple components of the immune system are responsible for renal injury and that any given patient can experience a combination of these mechanisms. With this in mind, specific therapies can be tested, and drugs that interrupt the immune response in highly specific ways are being scrutinized for their value in lupus nephritis. This new edition reflects the updated methods of classification and advances in treatment options for SLE, and covers recent clinical trials to help treat patients using the most up-to-date knowledge available. It takes a practical approach throughout, and will be of interest to those working with patients with lupus nephritis, and those who manage their everyday care.

A biomarker is a molecule that is measured as a marker of normal biological processes, disease processes or the response to a diagnostic or therapeutic intervention. Kidney diseases like acute kidney injury, chronic kidney disease, diabetic nephropathy, glomerular disease, renal cancer and preeclampsia still have a high morbidity. Measurement of biomarkers in the blood or urine that detect patients at risk of kidney diseases or that detect kidney diseases in the earliest stage may ultimately result in preventative or earlier or more effective treatments for kidney diseases. "Biomarkers of Kidney Disease" reviews the basic and clinical research on biomarkers of the common kidney diseases including acute kidney injury, chronic kidney disease, renal cancer, diabetic nephropathy, glomerular disease and preeclampsia. The characteristics of an ideal biomarker of kidney diseases and statistical analysis of biomarker studies is detailed. The latest techniques for biomarker detection like metabolomics and proteomics is covered in the book. This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation and preeclampsia. It presents a comprehensive, translational source for all aspects of renal biomarkers in one reference work. Experts in renal disease biomarkers (from all areas of academic and medical research) take readers from the bench research (cellular and molecular mechanism) to new therapeutic approaches.

Despite significant improvement in the management of patients with chronic kidney disease, the morbidity and mortality remain high. However more is now understood about the hormonal influence on bone and vascular structures, and there have been major advances in the field of bone and mineral metabolism. This has lead to the development of new treatment strategies and agents. This new second edition reflects the most current thinking and understanding in this fascinating field, as presented by world basic and clinical experts.

The kidneys are responsible for many key bodily functions, but their primary role as a filter of toxins makes them extremely susceptible to disease. Often these diseases can only be diagnosed through a renal biopsy, a complicated procedure requiring ancillary immunologic and molecular diagnostic techniques. This book covers all methods used by renal pathologists to diagnose a wide range of kidney diseases. Unlike most literature on renal pathology, this book is situated on the midpoint between encyclopedic and superficial coverage, written for the signing-out pathologist. While focusing on tumors and transplantation rejection, a full spectrum of infectious, inflammatory, and congenital disorders is covered in both pediatric and adult populations and is analyzed not only by light microscopy but by each applicable diagnostic modality available. The text is illustrated with more than 1,000 photomicrographs and diagrams, including a CD-ROM of all images.

Acute kidney failure is an important clinical area in the intensive care unit setting. An estimated 5-20 percent of critically ill patients experience an episode of acute kidney failure during the course of their illness, and about 5 percent of patients admitted to an ICU will eventually require renal replacement therapy. In these patients, in-hospital mortality is extremely high, exceeding 50 percent. Thus, the early detection and causal treatment of acute kidney problems is vitally important for a successful outcome. Written by internationally renowned experts, this clinical reference offers helpful advice with the most recent information on the definition, epidemiology, pathophysiology, and clinical causes of acute kidney failure as a fundamental prerequisite for prevention of this disorder. Moreover, it also covers differential diagnostic approaches for patients with acute renal failure and provides a detailed outline of important measures for their clinical management. Finally, separate chapters are dedicated to various key aspects related to the adequate delivery of acute renal replacement therapy. It is intended as a helpful guide for all clinicians involved in the care of patients at risk of developing acute kidney problems.