Terapia

E' la quinta edizione di un Manuale che che in soli venti anni è diventato un punto di riferimento nella formazione e nell'agg

This European Society of Cardiology (ESC) Handbook on Cardiovascular Pharmacotherapy has been developed by experts from the ESC Working Group on Cardiovascular Pharmacotherapy. Its recommendations are aligned with the ESC Clinical Practice Guidelines and based on the most recent scientific evidence in cardiovascular pharmacology and pharmacotherapy. The Handbook provides up-to-date information on pharmacotherapy for cardiovascular disease prevention, and treatment of cardiovascular disease, including ischaemic heart disease, heart failure, arrhythmias, and structural heart disease. The Handbook also deals with the important problems of cardiovascular pharmacotherapy in pregnancy and lactation, kidney insufficiency, and liver disease as well as focusing on major drug interactions, a topic of extreme importance in clinical practice. Two large sections of the book provide a comprehensive A-Z formulary of cardiac and non-cardiac pharmacological agents with practical and accessible information on the most important pharmacological aspects of these agents and their use in clinical practice. The Handbook represents essential reading for cardiologists, general practitioners, internal medicine specialists, anaesthetists, clinical pharmacologists, geriatricians, obstetricians, and cardiovascular nurse consultants. Junior doctors and trainees in all these specialties are also likely to find this book of help. The print edition comes with full access to the online version that will be updated at yearly intervals to keep it up to date.

Lo scopo di questo volume è quello di fornire una visione d’insieme e riassumere lo stato attuale delle conoscenze sulla terapia antiaggregante nel paziente acuto con un approccio prevalentemente, ma non esclusivamente, interventistico dedicando grande spazio a tutti i temi più innovativi sviluppati da esperti che trattano ogni giorno queste patologie nel laboratorio di emodinamica e in unità coronarica.Il cardiologo emodinamista è divenuto negli anni sempre più consapevole della problematica clinica del paziente e si è affiancato al cardiologo clinico di unità coronarica nella gestione del paziente con SCA, non riducendo più il suo intervento alla sala di emodinamica e alla trombosi dello stent, ma entrando nella totale complessità del quadro clinico, dell’accesso arterioso alla scelta della terapia antiaggregante piastrinica sia a breve sia a lungo termine.L’avvento di nuovi farmaci antiaggreganti orali in tutti i pazienti con SCA, al fine di superare il limite della variabilità di risposta individuale e il conseguente rischio di trombosi, ha determinato una riduzione rilevante degli eventi avversi successivi, con un aumento limitato degli effetti collaterali emorragici laddove si applica una corretta selezione dei pazienti.

This book is an essential guide to the medical treatment of the cardiac patient and presents core principles of cardiovascular therapeutics as well as drug recommendations. Major classes of drugs are featured, including beta-blockers, ACE inhibitors, calcium antagonists, diuretics, and antiplatelet agents and unique insights into the controversies surrounding the use of specific drugs are explored, with answers given to the question: do beta blockers and diuretics really cause diabetes? Properties, dosage, side effects, potential salutary benefits, and drawbacks on virtually all commercially available cardiac drugs are examined. This revised edition is thoroughly updated and addresses the entire spectrum of heart disorders, such as hypertension, angina, myocardial infarction, heart failure, arrhythmias, cardiac arrest, and dyslipidemias. New chapters include endocrine heart diseases, management of cardiomyopathies, and newer agents. In addition, topics such as cardiac drugs in pregnancy and lactation and drug interactions are covered. Cardiac Drug Therapy, Eighth Edition, is an authoritative and clinically relevant resource for cardiologists, cardiology fellows, and internists.

Cases in Cardiac Resynchronization Therapy, a brand-new medical reference book for cardiologists, electrophysiologists, surgeons, and primary care doctors, offers an informative and structured view of the newest approaches, treatments and follow-up care methods for heart failure patients treated with Cardiac Resynchronization Therapy. Complete with practical examples from top leaders in the field, this resource is designed to equip you with the cohesive, expert knowledge you need to make the best use of today's available technologies and research.

This companion to "Braunwald's Heart Disease" equips you with all of today's most effective therapeutic guidelines and management solutions for the full range of heart disease patients. It reflects the most recent standards for drug management as well as the latest in new technologies. Reorganized to mirror your changing practice, each cardiovascular-problem-based section offers a chapter on pharmacologic treatment (with a minimum of pathophysiology). This title includes a chapter on catheter-based or minimally invasive interventions and a discussion of surgical options. You'll also find a brand-new chapter on gene therapy and stem cell therapy, plus new chapters on many other rapidly developing areas of practice. The result is an outstanding single-volume source for state-of-the-art, clinically oriented guidance on both common and unusual areas of cardiovascular treatment.

Questo volume fornisce una sintesi chiara e aggiornata dell'epidemiologia, dei principali meccanismi fisiopatologici e delle modalità di valutazione clinica dell'insufficienza cardiaca, offrendo nel contempo un aggiornato approfondimento dell'ampio spettro di opzioni terapeutiche mediche attualmente disponibili. Tali opzioni comprendono strategie non farmacologiche, farmaci classicamente usati nella terapia dell'insufficienza cardiaca, quali digitale, diuretici e vasodilatatori, fino ai farmaci che agiscono sul sistema neuro-ormonale. Nel testo viene anche sottolineata la necessità di tenere conto, nella terapia dei pazienti con insufficienza cardiaca delle comorbidità, che soprattutto in età avanzata questi farmaci condizionano la qualità di vita e la prognosi di tali pazienti. Ampio spazio viene dato all'approccio e alla terapia delle sindromi di insufficienza cardiaca acuta così come sono discusse procedure cardiologiche più invasive quali l'impianto di cardiovertitori-defibrillatori, la terapia resincronizzante e l'impianto di sistemi di assistenza ventricolare. Sono introdotti anche concetti basilari che riguardano opzioni terapeutiche chirurgiche quali il trapianto cardiaco. Il volume è stato concepito come un punto di riferimento conciso, ma aggiornato e completo, per i medici coinvolti nel trattamento clinico dei pazienti con insufficienza cardiaca o i suoi fattori di rischio.

Frutto dell'esperienza del primo dipartimento cardiologico costituito in Italia, il "De Gasperis" di Milano, il manuale si propone come una guida pratica ed essenziale, fruibile a vari livelli, dallo specialista al medico di Medicina Generale. L'"italianità" del testo è evidente soprattutto nei riferimenti al modo di lavorare e alle dosi impiegate che si riferiscono ai protocolli terapeutici adottati nel nostro Paese, spesso diversi da quelli usati altrove e riportati nei testi più diffusi. Attraverso un ampio corredo di tabelle illustrative e flow-chart decisionali, sono affrontati in maniera sistematica ed esauriente gli argomenti più importanti in campo cardiovascolare alla luce dei risultati delle più recenti ricerche cliniche internazionali, segnalando chiaramente i benefici attesi e quelli riscontrati delle indicazioni e delle procedure terapeutiche considerate "di scelta" dal Dipartimento. Il medico è accompagnato passo passo nel processo decisionale, in particolare rispetto ad argomenti complessi come le procedure interventistiche coronariche e aritmologiche, le terapie chirurgiche cardiache e vascolari, la gestione dell'insufficienza cardiaca avanzata e il trapianto cardiaco, senza trascurare temi più tradizionali ma in rapida evoluzione, come le sindromi coronariche acute. Il manuale è, in sintesi, il tentativo di comunicare un "modo di lavorare" che integra la medicina basata sulle evidenze e cinquant'anni di esperienza nella cura delle malattie cardiovascolari.

Draws from expertise of leaders in antiplatelet therapy Easy-to-use layout enables rapid browsing Edited by a member of the prestigious TIMI study group with long-standing experience in the field

The multi-factorial nature of cardiovascular disease has important implications for the planning of effective treatment strategies. Lifestyle factors such as diet, smoking history and exercise combine with endogenous predictors such as ethnicity and family history to give every individual a unique risk profile. To achieve a better outcome for the patient, we first need to understand how these factors work, singly and in combination, to cause or accelerate progression of disease. With this knowledge, we can then develop more effective strategies for management that incorporate changes in lifestyle as well as pharmacological combination therapy for hypertension, dyslipidaemia, etc. In this volume, the authors demonstrate how an ability to measure and quantify risk enables us to isolate key predictors of morbidity and informs the formulation of appropriate treatment strategies.

"Therapeutic Strategies in Heart Failure" is a pragmatic textbook written by active clinicians and investigators that is sharply focused on what the doctor needs to know to achieve the best possible outcome in patients with heart failure. The authors have incorporated all of the most recent definitive trial data, in a user friendly format, with frequent summary boxes and highlighted points of emphasis. The book begins with the prevention of heart failure, discusses best application of standard therapies, describes progress with current cutting edge treatments, and anticipates future therapeutic interventions. To complete the thought process, the final section deals with the avant garde issues in heart failure - the use of registry data, acute decompensated heart failure, device therapy, mechanical support for failing ventricles and a candid discussion of palliative care. The busy clinician is likely to find that "Therapeutic Strategies in Heart Failure" provides a useful template to optimize outcomes in the management of heart failure.

Appreciation of the importance of platelets and coagulation factors in therothrombotic events has led to the widespread use and continuous development of new antithrombotic agents. This field of cardiovascular pharmacology has advanced at a very rapid rate. Understanding the basic principles of atherothrombosis as well as the pharmacological agents currently available or under clinical development are key to the successful treatment of patients with atherothrombotic manifestations, particularly coronary artery disease. Clinical Guide to the Use of Antithrombotic Drugs in Coronary Artery Disease presents the work of internationally renowned contributors who examine pharmacological principles, indications for use, and pitfalls of antithrombotic agents most commonly utilized in treating patients with coronary artery disease. They also describe special clinical scenarios which may call for a multi-pharmacological approach or which demonstrate various undesired effects of antithrombotic agents.

This is a newly updated second edition of Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics. William B. White, MD, and a panel of highly experienced clinicians critically review every aspect of out-of-office evaluation of blood pressure. The world-class opinion leaders writing here describe the significant advances in our understanding of the circadian pathophysiology of cardiovascular disorders.