Jame Abraham, Walter Stadler
editore: Demos Medical Publishing
This issue of "Emerging Cancer Therapeutics" provides a comprehensive review for practitioners on the current status of renal cancer treatment. Renal cancer treatment has undergone major changes over the course of the past few years and "Renal Cancer" addresses current best practices in the light of the most recent evidence. All of the chapters are written by international experts in the field, address the common clinical scenarios in renal cancer and are multidisciplinary in scope covering surgical, medical, and radiation therapy. This book includes chapters examining emerging and novel therapeutic targets, and the management of both CNS, and skeletal metastases in renal cancer round out the coverage. It features: editorial board of nationally recognized experts across the spectrum of Cancer Therapeutics; in-depth, up-to-date expert reviews and analysis of major new developments in all areas of Cancer Therapeutics; and issues edited by an authority in specific subject area. It focuses on major topics in Cancer Therapeutics with in-depth articles covering advances in clinical and translational research developments, as well as clinical applications and experience. It emphasizes multidisciplinary approaches to research and practice.
Cancer and the Kidney
The Frontier of Nephrology and Oncology
Eric P. Cohen
editore: Oxford University Press
Cancer and the Kidney covers the challenging overlap area of nephrology and oncology. Kidney problems in cancer patients, and cancer that affects kidney patients, are both very real clinical issues in medicine. For example, cancer is a common complication of kidney transplantation, and up to half of all survivors of bone marrow transplant may develop chronic kidney disease. Since publication of the first edition in 2005, there have been many changes in this area. These include the recognition of chronic kidney disease after uninephrectomy for cancer, the occurrence of medication toxicities of the EGFR antagonists and of the VEGF antagonists, and changes in the approach to multiple myeloma. In this new edition, the primary authors cover diverse subjects in this area, ranging from assessment of kidney function, to paraneoplastic disorders, acquired cysts and native kidney cancers, and all points inbetween. Each chapter starts with a case study to ensure a practical focus, and there are numerous illustrations throughout. Specialists and trainees in nephrology and in oncology will find it a useful starting point and reference, as will physician assistants and nurse practitioners who work in these fields.
Il carcinoma renale
Basi per un moderno approccio multidisciplinare
a cura di V. Ficarra, C. Porta
editore: Il Pensiero Scientifico
Renal and Adrenal Tumors
Biology and Management
Alastair W. S. Ritchie, Arie Belldegrune altri
editore: Oxford University Press
In the past decade there has been an explosion of far-reaching developments in the biological and physical sciences relevant to cancer. The incidence and mortality from renal cell carcinoma has continuously risen over the past 50 years. Despite this, survival for patients has notably improved and great strides have been made in the management of patients with renal cell carcinoma. Our understanding of the natural history of renal cell carcinoma, the role of nephrectomy, the benefits of immunotherapy and the possibilities of new technologies are evolving and are being integrated with advances in classification and staging. This book provides a comprehensive source of information on renal and adrenal tumors that will be of practical interest for students, residents, physicians, and researchers alike. It reviews comprehensively the current understanding of the biology, pathophysiology and urological oncology of the disease, looking at the clinical problems and potential solutions including chapters on both the scientific and clinical principles. Fully illustrated, the book emphasises new advances in molecular biology, pathogenesis, detection and experimental therapeutics and focuses on new developments in clinical research. An international team of recognized of experts have been brought together to provide historical perspectives, an overview of basic facts, and an assessment and exploration of the newer developments in our understanding of the clinical, genetic, and molecular aspects of these diseases. The book clearly distinguishes what is generally agreed upon from what is still controversial, giving both sides equal treatment.
Histological Typing of Prostate Tumours
Charles J. Davis, I. A. Sesterhenne altri
editore: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
This classification is based primarily on the microscopic characteris- tics of tumours and therefore is concerned with morphologically identifiable cell types and histological patterns as seen with conven- tional light microscopy. The term tumour is used synonymously with neoplasm. The phrase tumour-like is applied to lesions that clinically or morpholog- ically resemble neoplasms but do not behave biologically in a neo- plastic manner. They are included in this publication because they give rise to problems in differential diagnosis and because of the un- clear distinction between neoplasms and certain non-neoplastic le- sions. Synonyms are listed only if they have been widely used or are considered helpful for the understanding of the lesion. In such cases, the preferred term is given first and followed by the synonym. The current revision includes the recognition of a preinvasive le- sion, prostatic intraepithelial neoplasia, which is commonly associat- ed with carcinoma. It also recognises the paracrine-endocrine ele- ments in prostate carcinoma and other subtypes of adenocarcinoma. Although the emphasis of the classification is on histological typ- ing, consideration should also be given to the degree of differentia- tion and nuclear anaplasia, extent of local spread, vascular and lym- phatic invasion, and the occurrence of metastasis. The revision in- cludes grading (p. 14), staging (p. 32), and handling and reporting of the different types of specimens (p. 1).