Opere di carattere generale

Nel 2003, quando fu pubblicata la prima edizione di questo volume, riviste e quotidiani nazionali annunciavano la fine dell'era degli antibiotici.Il loro monito rimane valido anche nel 2019. L'incidenza delle infezioni causate da batteri multiresistenti (MDR) continua ad aumentare e oggi le infezioni da MDR rappresentano una delle principali cause di danno prevenibile nei nostri ospedali.La colite da Clostridium difficile si è diffusa tra molti dei pazienti più vulnerabili come conseguenza dell'uso continuativo di antibiotici ad ampio spettro, che consentono a questo patogeno di proliferare e di rilasciare citotossine nel tratto gastrointestinale. L'HIV rimane una sfida a livello globale, in particolare nel continente africano.Virus e batteri continuano a emergere come minacce per l'uomo, tra cui MERS, virus Ebola e virus Zika. Come conseguenza del riscaldamento globale, la stagione delle zecche si è progressivamente allungata, aumentando l'incidenza della malattia di Lyme, dell'infe-zione da Ehrlichia e di altre patologie trasmesse da zecche. Il riscaldamento globale promette inoltre di ampliare la diffusione di altre infezioni trasmesse da insetti, tra cui malaria, virus Chikungunya e dengue.Come mai prima d'ora, i clinici necessitano di una solida comprensione delle malattie infettive e di un approccio logico ed economicamente sostenibile alla loro diagnosi e al loro trattamento. Negli Stati Uniti il costo dell'assistenza sanitaria è divenuto proibitivo, assorbendo oltre il 18% del prodotto interno lordo (PIL), e molti degli anti-infettivi necessari per trattare infezioni da MDR sono estremamente costosi.Inoltre, tali infezioni si associano a ricoveri prolungati e a un rischio più elevato di danno permanente o morte. L'era dell'uso indiscriminato di antibiotici ad ampio spettro è terminata.I programmi di antibiotic stewardship limitano oggi l'impiego di molti di questi farmaci con l'obiettivo di rallentare la progressiva selezione di batteri e virus multiresistenti. Una comprensione fondamentale delle malattie infettive consente al clinico di richiedere in modo proattivo esami diagnostici ad alto rendimento e di prescrivere l'anti-infettivo appropriato, evitando la necessità di interagire con i programmi di stewardship antibiotica.Ma come può il clinico impegnato o lo studente delle professioni sanitarie raggiungere tale obiettivo? Malattie infettive: un corso clinico breve è concepito per essere letto in 30 giorni. Sotto il titolo di ciascun capitolo è indicato il tempo suggerito per la lettura.I punti chiave sono evidenziati in riquadri per favorire il ripasso e la preparazione agli esami di specialità e ai programmi di mantenimento della certificazione (MOC).Tabelle riassumono presentazioni cliniche critiche, dosaggi e costi degli antibiotici, tossicità degli anti-infettivi, mentre le figure illustrano visivamente lo spettro di attività di ciascun antibiotico.In ogni capitolo sono inclusi casi clinici reali per illustrare la presentazione delle diverse malattie; ogni caso è seguito da un illness script (dichiarazione riassuntiva) per migliorare il riconoscimento dei pattern clinici e affinare le competenze diagnostiche.

A distanza di 12 anni, la nona edizione di Malattie infettive segna il ritorno di uno dei testi tradizionali della disciplina in Italia, profondamente aggiornato alla luce dei rapidi progressi epidemiologici, diagnostici e terapeutici e dell'esperienza maturata negli anni della pandemia.L’opera mantiene l’impostazione originale basata sull’approccio sindromico, una scelta che da oltre trent’anni ne orienta la struttura e supporta il percorso interpretativo del clinico, dello studente e dello specializzando.Il volume presenta un’articolazione profondamente rinnovata, frutto della collaborazione dei maggiori esperti italiani nei diversi settori dell’infettivologia. La trattazione si apre con capitoli di inquadramento generale che affrontano gli aspetti epidemiologici, immunopatogenetici, diagnostici e terapeutici, aggiornati alla luce delle più recenti acquisizioni scientifiche.In questa edizione entrano per la prima volta contributi dedicati alla progettazione e interpretazione degli studi clinici in infettivologia e ai programmi di antimicrobial stewardship, insieme a un nuovo capitolo sulla farmacologia clinica applicata alle malattie infettive. La sezione dedicata alle infezioni di organi e apparati è completamente aggiornata e ampliata.Accanto alla revisione delle patologie esistenti – in particolare delle infezioni respiratorie, dove trova spazio l’integrazione della malattia da SARS-CoV-2, e delle infezioni del sistema nervoso, cardiovascolare, digerente, urogenitale ed emopoietico – vengono introdotti nuovi capitoli sulle infezioni intraddominali, sulle infezioni da batteri multi-farmacoresistenti, sulle infezioni nel ricevente di trapianto di organo solido e sulle infezioni nel ricevente di trapianto di cellule staminali emopoietiche.Completano il quadro la trattazione aggiornata delle: micobatteriosi, delle epatiti virali, infezioni del fegato e delle vie biliari, infezioni dell’apparato visivo, uditivo, ghiandole salivari. Ampio spazio è dedicato agli ospiti speciali, includendo capitoli interamente nuovi sulle infezioni in altri ospiti immunocompromessi e sulle peculiarità cliniche dei pazienti sottoposti a terapie con farmaci biologici. Vengono aggiornate le sezioni relative alle infezioni nosocomiali, alle infezioni nell’anziano, al rischio infettivo del viaggiatore e alla profilassi vaccinale, con l’inserimento del calendario vaccinale attuale e dei nuovi vaccini introdotti negli ultimi anni.Arricchito da iconografia, tabelle di sintesi e box di approfondimento, Malattie infettive 9a ed. nasce dal contributo coordinato di autorevoli specialisti e coniuga rigore scientifico ed esperienza clinica. In un contesto dominato da aggiornamenti rapidi e frammentari, quest'opera unitaria si propone come guida affidabile per lo studio e la pratica quotidiana. Un manuale pensato per studenti, specializzandi e professionisti, che accompagna la formazione medica da oltre quarant'anni e costituisce un riferimento autorevole e attuale per la gestione delle patologie da infezione.

Il Manuale di Medicina e Chirurgia nasce per offrirti una fonte di studio univoca nella preparazione ai Concorsi SSM e MMG, su

Fully reviewed and revised for its third edition, the Oxford Handbook of Infectious Diseases and Microbiology remains the invaluable guide to all aspects of infectious diseases and microbiology. Reflecting the current approach to joint postgraduate training programmes, the handbook takes an integrated approach to both subjects. It covers the basic principles of bacteriology and virology, along with specific guidance on individual diseases and conditions, all in the accessible Oxford Handbook style. The chapters have been expanded to include new developments that reflect the fast-changing field of infectious diseases and their managements, including novel pathogens such as SARS-CoV-2 and updated treatments for infections such as Hepatitis C. Diagnostic technologies such as whole-genome sequence based approaches are covered in greater detail, and the increased role of antimicrobial stewardship in the management of antiviral and antifungal prescribing has been substantially reviewed since the previous edition. Practical and comprehensive, this handbook includes coverage of current legislation and guidelines, as well as substantial changes to species nomenclature. Fully reviewed by specialist senior clinicians, and with useful links to up-to-date clinical information and online resources, this title remains a cornerstone for all infection trainees, those working in laboratory settings, and candidates preparing for infection examinations such as CICE and FRCPath.

Questo volume, lungi dall'essere un trattato esaustivo e sistematico, si propone di descrivere in modo sintetico le malattie i

**Selected for 2026 Doody's Core Titles as an Essential Purchase in Infectious Disease** Widely used by students, residents, generalists, and specialists, Netter’s Infectious Diseases, 2nd Edition delivers must-know information on infectious diseases in a highly illustrated, easily accessible format. Concise visual overviews of essential topics provide a convenient, trustworthy way to review the basics of a given infectious disease or issue or to share with patients or staff. Drs. Elaine Jong and Dennis Stevens cover the wide spectrum of illness and disease in this complex field using memorable illustrations by world-renowned artist Frank H. Netter and others, offering a time-saving, authoritative look at infectious disease risk factors, clinical presentations, pathophysiology, and more. Covers major conditions and problems such as vaccine-preventable diseases, drug-resistant staph, community acquired pneumonia, surgical infections, pyelonephritis, viral hepatitis, and sexually transmitted infections-and provides updated approaches to diagnosis, treatment, prevention, and standards of care Includes new clinical vignettes added to most chapters Provides updated and expanded coverage of emerging infectious diseases such as multidrug resistant tuberculosis (MDR-TB), neuroangiostrongyliasis (rat lungworm disease), Ebola virus, Severe Acute Respiratory Disease (SARS), Middle East Respiratory Syndrome (MERS), Coronavirus Infectious Disease-2019 (COVID-19), and novel influenza viruses including public health concerns Covers vector-borne diseases including malaria, yellow fever, Zika infections and congenital Zika syndrome, West Nile fever, Lyme disease, tick-borne encephalitis, and Chagas disease plus others New chapters on travelers’ diarrhea, cholera, and primary amebic meningoencephalitis debut in the section on international travel and outdoor activities Contains memorable parasite life cycles and unforgettable parasite infection clinical vignettes Features unparalleled illustrations by Drs. Frank H. Netter, Carlos Machado, and others, as well as radiologic images Provides 24 printable patient education brochures in the enhanced ebook Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices

 Master the principles of clinical infectious disease in 30 days or less! A Doody's Core Title for 2023, 2024 & 2026!  Infectious Diseases: A Clinical Short Course, Fourth Edition provides busy physicians, students, nurse practitioners, and PAs with the kind of concise overview they need to understand, diagnose, and treat common infectious diseases safely and effectively.  Organized by system/region—as opposed to pathogens—to simulate the ways you encounter common pathogens and disorders in rounds or in practice, this new edition includes key updates and aligns content with information tested on the USMLE Step 2. By indicating the number of days you should spend on each chapter, the author has created a schedule for completion of each lesson. A wide array of tables summarizing the methods of clinical assessment, anti-infective agent doses, and drug toxicities—critical facts that do not require memorization, but need to be referred to when caring for patients—facilitate this condensed learning schedule. Key Points summarize the most important facts you need to know when managing each infection and facilitate board review Guiding Questions kick off each chapter An estimate of the potential severity of each disease provides insight into how quickly you should initiate treatment Case examples highlight real-world clinical application of the content Dozens of color plates depict major pathogens All chapters have been updated to reflect the most current treatment and diagnostic guidelines from the Infectious Diseases Society of America

Gli ultimi anni sono stati cruciali per lo studio delle malattie infettive

Selected as a Doody's Core Title for 2025! Concise, portable, and user-friendly, The Washington Manual™ Infectious Diseases Subspecialty Consult, Third Edition, provides essential information needed to evaluate patients on a subspecialty consult service.  This edition offers state-of-the-art content on the diagnosis, investigation, and treatment of a wide variety of infectious diseases, including coverage of new and emerging pathogens, rapid molecular diagnostics for infectious diseases, and new therapeutic and preventive strategies. Ideal for trainees and practicing physicians who need quick access to current scientific and clinical information in this rapidly changing area, the manual is also useful as a first-line resource for internists and other primary care providers. Content has been thoroughly revised from cover to cover, including two new chapters: Antimicrobial Stewardship and Arboviruses and Hemorrhagic Fevers. A highly templated, bulleted format ensures you can find what you need quickly and easily. Comprehensive coverage includes fever of unknown origin, sexually transmitted infections, opportunistic infections associated with HIV, zoonotic and tickborne infections, protozoal infections, infection prevention, and much more. Text has been organized by organ system to facilitate generating a useful differential diagnosis based on a patient’s presentation. Written by faculty and fellows from the Infectious Diseases Division of Internal Medicine at the Washington University School of Medicine in St. Louis.  Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

Brought to you by the expert editor team from Principles and Practice of Infectious Diseases, this brand-new handbook provides a digestible summary of the 245 chapters contained within the parent text. Boasting an exceptionally templated design with abundant tables and illustrations, it distills the essential, up-to-date, practical information available in infectious disease and organizes it by Body System. This high-yield manual-style reference will prove useful for everyone from primary care doctors, emergency physicians, and nurses, to global health care workers, students, and pharmacists alike.

La nuova edizione nasce dall'esigenza di assicurare l'aggiornamento a una disciplina in dinamica evoluzione e sempre più al centro delle competenze non soltanto dello specialista, ma anche del medico di medicina generale. Si avvale, pertanto, dell'autorevole collaborazione di nuovi editor e contributor, che con la loro esperienza clinica e didattica hanno sistematicamente aggiornato i contenuti alla luce delle più recenti acquisizioni epidemiologiche, eziologiche, microbiologiche, diagnostiche e terapeutiche, sempre nell'ottica di focalizzare le informazioni essenziali per la preparazione dello studente del Corso di Laurea in Medicina & Chirurgia. Restano confermati, al contempo, l'articolazione snella e fruibile, il taglio didattico facilitato da key point, focus on, non dimenticare che, strumenti e punti di sintesi e focalizzazione dei contenuti che insieme alla loro autorevolezza hanno sancito l'affermazione dell'opera.

As doctors and biologists have learned, to their dismay, infectious disease is a moving target: new diseases emerge every year, old diseases evolve into new forms, and ecological and socioeconomic upheavals change the transmission pathways by which disease spread. By taking an approach focused on the general evolutionary and ecological dynamics of disease, this Very Short Introduction provides a general conceptual framework for thinking about disease. Ecology and evolution provide the keys to answering the 'where', 'why', 'how', and 'what' questions about any particular infectious disease: where did it come from? How is it transmitted from one person to another, and why are some individuals more susceptible than others? What biochemical, ecological, and evolutionary strategies can be used to combat the disease? Is it more effective to block transmission at the population level, or to block infection at the individual level? Through a series of case studies, Benjamin Bolker and Marta L. Wayne introduce the major ideas of infectious disease in a clear and thoughtful way, emphasising the general principles of infection, the management of outbreaks, and the evolutionary and ecological approaches that are now central to much research about infectious disease. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Infectious disease surveillance has evolved at an extraordinary pace during the past several decades, and continues to do so. It is increasingly used to inform public health practice in addition to its use as a tool for early detection of epidemics. It is therefore crucial that students of public health and epidemiology have a sound understanding of the concepts and principles that underpin modern surveillance of infectious disease. Written by leaders in the field, who have vast hands-on experience in conducting surveillance and teaching applied public health, Concepts and Methods in Infectious Disease Surveillance is comprised of four sections. The first section provides an overview, a description of systems used by public health jurisdictions in the United States and legal considerations for surveillance. The second section presents chapters on major program-area or disease-specific surveillance systems, including those that monitor bacterial infections, foodborne diseases, healthcare-associated infections, and HIV/AIDS. The following section is devoted to methods for conducting surveillance and also approaches for data analysis. A concluding section summarizes communication of surveillance findings, including the use of traditional and social media, in addition to showcasing lessons learned from the New York City Department of Health's experience in surveillance and epidemiology training. This comprehensive new book covers major topics at an introductory to intermediate level, and will be an excellent resource for instructors. Suitable for use in graduate level courses in public health, human and veterinary medicine, and in undergraduate programs in public-health-oriented disciplines, Concepts and Methods in Infectious Disease Surveillance is also a useful primer for frontline public health practitioners, hospital epidemiologists, infection control practitioners, laboratorians in public health settings, infectious disease researchers, and medical and public health informaticians interested in a concise overview of infectious disease surveillance.

Avian Influenza Virus, Second Edition aims to provide the essential methods used in working with animal influenza viruses, and to compile more advanced information that will guide the user in designing influenza studies. Influenza A viruses are among the most important pathogens for humans, food animals and companion animals. Research and diagnostics with animal influenza viruses are critical to animal health and it should be recognized that the needs and goals of animal agriculture and veterinary medicine are not always the same as those of public health. This volume sorts out the differences in the structure of the poultry, swine and equine industries, the biological differences of influenza virus from each animal group, and provides host, strain and lineage specific guidance and procedures. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Avian Influenza Virus, Second Edition seeks to serve both professionals and novices with its well-honed methodologies in an effort to further our knowledge of these important pathogens.

Infectious Diseases - as only Harrison's can cover it. Featuring a superb compilation of chapters related to infectious diseases that appear in "Harrison's Principles of Internal Medicine, Eighteenth Edition", this concise, full-color clinical companion delivers the latest knowledge in the field backed by the scientific rigor and authority that have defined Harrison's. You will find content from renowned editors and contributors in a carry-anywhere presentation that is ideal for the classroom, clinic, ward, or exam/certification preparation. It features: current, complete coverage of need-to-know topics, including infections in organ systems, bacterial infections, viral infections, prion diseases, fungal infections, and protozoal infections; Addresses underlying epidemiologic, pathophysiologic, and genetic factors; important material on HIV infections and AIDS by Anthony S. Fauci and H. Clifford Lane; two image-based chapters comprise atlases valuable to clinical assessment: rashes associated with fever and blood smears of the various stages of the parasites causing malaria and babesiosis; integration of pathophysiology with clinical management. 121 high-yield questions and answers drawn from "Harrison's Principles of Internal Medicine Self-Assessment and Board Review, 18e"; content updates and new developments since the publication of "Harrison's Principles of Internal Medicine, 18e"; 132 chapters written by physicians who are recognized experts in the field of infectious diseases; and helpful appendix of laboratory values of clinical importance.

Using the two-page, templated organization of "The 5-Minute Consult" series, "Gorbach's 5-Minute Infectious Diseases Consult, Second Edition" provides comprehensive coverage for clinicians dealing with infectious diseases. The two major sections of the book cover chief complaints and individual diseases and disorders. Additional materials include summary information about individual microorganisms as well as numerous elements related to drugs for infectious disorders. A team of international authorities provides actionable information, supported by current research and practice guidelines. It includes features such as: comprehensive coverage of infectious diseases, important symptoms, microorganisms, and anti-infective drugs; coverage of emerging infectious diseases such as H1N1 flu; increased coverage of tropical diseases; two-page, tightly written chapters; and, updated information about management of HIV/AIDS.