"Thyroid Cancer" describes all current diagnostic techniques, including FDG-PET and MRI. In recent years, these modalities have documented hitherto hidden radioiodine-negative metastases, thus improving surgical therapy. The whole gamut of treatment, including surgery, radioiodine therapy, percutaneous radiation therapy and medical management, is covered. In some 10 per cent of differentiated thyroid cancers, the well-known treatment tools of surgery and radioiodine therapy are not sufficient. New treatment modalities such as high-dose radioiodine therapy, redifferentiation therapy with retinoic acid and recombinant TSH are therefore highlighted. In a special section devoted to medullary thyroid cancer, new imaging procedures such as octreotide scintigraphy are described. The second edition includes two new chapters, on I-124 PET and dosimetry. Other chapters have been modified particularly in view of the new UICC classification, with special regard to the definition of T1 tumors.
Basics.- The Changing Epidemiology of Thyroid Cancer.- Histopathology, Immunohistochemistry, and Molecular Biology.- Familial Differentiated Carcinoma of the Thyroid.- The Diagnosis of Thyroid Cancer.- The Current Surgical Approach to Non-Medullary Thyroid Cancer.- Differentiated Thyroid Cancer.- Radioiodine Therapy for Thyroid Cancer.- 124I Positron Emission Tomographic Dosimetry and Positron Emission Tomography/Computed Tomography Imaging in Differentiated Thyroid Cancer.- External Beam Radiotherapy.- Thyroid Cancer: Treatment with Thyroid Hormone.- Treatment with Cytotoxic Drugs.- Redifferentiation Therapy of Thyroid Carcinomas with Retinoic Acid.- Follow-up of Patients with Well-Differentiated Thyroid Cancer.- Thyroglobulin as Specific Tumor Marker in Differentiated Thyroid Cancer.- Functional Imaging of Differentiated Thyroid Cancer.- Magnetic Resonance Imaging.- Thyroid Cancer in Chernobyl Children.- Medullary Thyroid Cancer.- Diagnosis of Medullary Thyroid Cancer.- Imaging in Medullary Thyroid Cancer.- Therapy for Medullary Thyroid Cancer.- Follow-up of Medullary Thyroid Cancer.