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Lupus eritematoso

Systemic Lupus Erythematosus

George Tsokos, Jill Buyon
e altri

editore: Academic Press Inc

pagine: 1154

Systemic lupus erythematosus (S.L.E.), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness, or remission. Because its symptoms come and go and mimic those of other diseases, lupus is difficult to diagnose. There is no single laboratory test that can definitively prove that a person has the complex illness. To date, lupus has no known cause or cure. Early detection and treatment is the key to a better health outcome and can usually lessen the progression and severity of the disease. Anti-inflammatory drugs, anti-malarials, and steroids (such as cortisone and others) are often used to treat lupus. Cytotoxic chemotherapies, similar to those used in the treatment of cancer, are also used to suppress the immune system in lupus patients. A new edition of this established and well regarded reference which combines basic science with clinical science to provide a translational medicine model. Systemic Lupus Erythematosus is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease and a reference work for hospital libraries. * Highly illustrated and in full colour throughout * Basic science section expanded to allow the reader to focus on the newest techniques in molecular medicine and its effects on disease expression and treatment * Clinical aspects and new drugs will be covered in great detail providing a useful reference to both experienced clinicians and physicians with an interest in lupus in their clinical practice
198,00 168,30

Systemic Lupus Erythematosus

Caroline Gordon, George C. Tsokos
e altri

editore: Mosby

pagine: 608

This new companion to "Hochberg et al.'s Rheumatology" masterwork provides new insights into the causes, detection and therapy of this challenging disease. In this state-of-the-art resource, you'll find 'one stop' coverage of all the latest scientific and clinical developments in SLE: new concepts in epidemiology, disease activity measures and outcomes; new concepts in immunoregulation, genetic and pathogenic mechanisms; new understanding and novel presentation of the processes of tissue/organ damage; comprehensive coverage of clinical features; and the very latest concepts in treatment.
111,00 94,35

Dubois' Lupus Erythematosus

Bevra Hannahs Hahn, Daniel J. Wallace
e altri

editore: Lippincott Williams and Wilkins

pagine: 1440

Established for forty years as the definitive reference on lupus, Dubois' Lupus Erythematosus is now in its thoroughly revised, updated Seventh Edition. More than ninety distinguished contributing authors--twenty of them new to this edition--provide comprehensive coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. This edition focuses on evidence-based findings, treatment consensuses, and practical clinical information. New chapters cover cytokines and interferons, pathogenesis of atherosclerosis, immune tolerance, clinical indices in assessment of lupus, mixed connective tissue disease, reproductive issues, fibromyalgia, gender-related issues, and biomarkers.
214,00 181,90

Dubois' Lupus Erythematosus

Bevra Hannahs Hahn, Daniel J. Wallace

editore: Lippincott Williams and Wilkins

pagine: 1376

Thoroughly revised and updated for its Sixth Edition, Dubois' "Lupus Erythematosus" remains the definitive reference on this disease. More than sixty distinguished authorities provide comprehensive coverage of every aspect of cutaneous and systemic lupus erythematosus -including definition, classification, epidemiology, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. This edition's clinically oriented chapters include timely information on the new classification for lupus, undifferentiated connective tissue disease, biologic therapies, cox-2 interventions, clinical trial methodologies, and outcomes research. Completely rewritten basic science sections reflect recent findings on genetics, inflammatory mediator biology, cytokine physiology, cell signaling, and newly described animal models and autoantibodies. This is a Brandon-Hill recommended title.
272,00 231,20

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