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Libri di M. A. Hayat

Tumors of the Central Nervous System

M. A. Hayat

editore: Springer

pagine: 404

In this title, the classification of brain tumors is up-dated using magnetic resonance spectroscopy technology. The role of cellular immortality in brain tumors is reviewed. Tumor to tumor metastases are a common occurrence; for example, brain metastasis from breast cancer, lung cancer, and renal cancer is discussed. Genetic profiling and treatment (including neurosurgery) of such brain cancers are explained. Breast cancer patients treated with certain drugs (e.g., capecitabine and lapatinib can develop CNS tumors. Role of brain tumor suppressor genes (e.g., NRP/B gene) is pointed out. Biomarkers used to diagnose brain malignancies are explained in detail. A number of imaging modalities used for diagnosing and assessing the effectiveness of treatments of brain tumors are presented. The imaging methods discussed include MRI, PET, CT, MRSi, and SPECT. Also discussed is the impact of PET using radiolabeled amino acids on brain tumors.
165,00 140,25

Methods of Cancer Diagnosis, Therapy and Prognosis

Colorectal Cancer

M. A. Hayat

editore: Springer-Verlag New York Inc.

pagine: 541

This volume discusses various methodolo- discoveries and their translation to clinical gies for the diagnosis, therapy, and prog- practice. Oncology will benefit the most nosis of colorectal cancer (CRC). Volumes from these various advanced methodologies, 1, 2, 3, and 4 of this series present similar as a combination of the rapies and person- methods for breast cancer, lung and pros- ized medicine will improve early detection tate cancers, and gastrointestinal cancer, of CRC and other cancer types. respectively. The current volume presents The use of anticancer agents, including surgical, radiological, and molecular thera- 5-fluorouracil, fluoropyrimidines, leuc- pies and prognostic biomarkers for CRC. orin, irinotecan, oxaliplatin, raltitrexed, A large number of methods, including capecitabine, cetuximab, and bevacizumab, immunohistochemistry, in situ hybridiza- is also presented. Preoperative chemora- tion, immunoscintigraphy, RT-PCR, free otherapy is compared with postoperative circulating DNA levels in blood and stool, chemoradiotherapy. In addition, treatments ultrasonography, CT, PET, and MRI are such as immunotherapy, laparoscopic detailed for diagnosing CRC at various surgery, radiofrequency ablation, pho- stages of development. Imaging technolo- dynamic therapy, and preoperative che- gies for assessing the treatment results are radiotherapy, are presented. Preoperative also included as are details related to colon- short-course radiation for resectable r- oscopy and sigmoidoscopy. In addition, the tal cancer is also detailed. role of mircoRNA as a biomarker for this This volume included the efforts of 89 type of cancer is elaborated.
209,00 177,65

Methods of Cancer Diagnosis, Therapy and Prognosis

Breast Carcinoma

M. A. Hayat

editore: Springer-Verlag New York Inc.

pagine: 776

The enormity of the global healthcare costs vical. One-fifth of all cancers worldwide as a result of cancer infliction cannot be are caused by a chronic infection, for overemphasized. There are more than 100 example, human papilloma virus (HPV) types of cancers; any part of the body can causes cervical cancer and hepatitis B be affected. More than 11 million people virus (HBV) causes liver cancer. Tobacco are diagnosed with cancer every year, and use is the most common preventable cause it is estimated that there will be 16 mil- of cancer in the world. Approximately, lion new cases per year by the year 2020. 168,000 cancer deaths are expected to be In 2005, 7. 6 million people died of can- caused by tobacco use. Approximately, cer, that is, 13% of the 58 million deaths 40% of cancer could be prevented, mainly worldwide. It is estimated that 9 million by not using tobacco, having a healthy people will die from cancer worldwide in diet, being physically active, preventing 2015 and 11. 4 million will die in 2030. infections that may cause cancer, reduc- More than 70% of all cancer deaths occur ing exposure to sunlight, and avoidance of in low and middle income countries. excessive alcohol consumption and stress Five major cancer causing overall mor- (anger). A third of cancers could be cured talities per year worldwide are (WHO): if detected early and treated adequately. It is well established that scientific 1. Lung: 1.
220,00 187,00

Cancer Imaging

M. Hayat

editore: Academic Press Inc

pagine: 1584

With cancer related deaths projected to rise to 10.3 million people by 2020, the need to prevent, diagnose, and cure cancer is greater than ever. These two volumes present readers with the most up-to-date imaging instrumentation, general and diagnostic applications for various cancers. Both volumes discuss the various imaging techniques used to locate and diagnose tumors, including ultrasound, X-ray, color Doppler sonography, PET, CT, PET/CT, MRI, SPECT, diffusion tensor imaging, dynamic infrared imaging, and magnetic resonance spectroscopy. They also detail strategies for imaging cancer, emphasizing the importance of the use of this technology for clinical diagnosis. Imaging techniques that predict the malignant potential of cancers, response to chemotherapy and other treatments, recurrence, and prognosis are also detailed.
265,00 225,25

Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas

Molecular Genetics, Gastrointestinal Carcinoma, and Ovarian Carcinoma

M. A. Hayat

editore: Academic Press Inc

pagine: 608

Classical histology has been augmented by immunohistochemistry (the use of specific antibodies to stain particular molecular species in situ). Immunohistochemistry has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system. This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. This is the only book available that translates molecular genetics into cancer diagnosis. The methods were developed by internationally-recognized experts and presented in step-by-step manner. The results of each Immunohistochemical and in situ hybridization are presented in the form of color illustrations.
207,00 175,95

Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas

Molecular Pathology, Colorectal Carcinoma, and Prostate Carcinoma

M. A. Hayat

editore: Academic Press Inc

pagine: 492

Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer. This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today. This book is the second volume of three planned, individually-sold volumes on this topic. Like Volume 1, this book fully explains the principles and applications of modern techniques used in the field of molecular genetics. It will be of particular interest to pathologists and molecular pathologists conducting both academic and/or clinical research. It is the only book available that translates molecular genetics into cancer diagnosis. The results of each Immunohistochemical and in situ hybridization method are presented in the form of color illustrations. The methods discussed were either developed or refined by expert contributors in their own laboratories.
190,00 161,50

Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas

Molecular Genetics: Liver and Pancreatic Carcinomas

M. A. Hayat

editore: Academic Press Inc

pagine: 432

Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer. This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today. This is the only book available that translates molecular genetics into cancer diagnosis. The results of each Immunohistochemical and in situ hybridization method are presented in the form of color illustrations. The methods discussed were either developed or refined by expert contributors in their own laboratories.
207,00 175,95

Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas

Molecular Genetics - Lung and Breast Carcinomas

M. A. Hayat

editore: Academic Press Inc

pagine: 556

The various cell types have traditionally been recognized and classified according to their appearance in the light microscope following the process of fixing, processing, sectioning, and staining tissues that is known as histology. Classical histology has been augmented by immunohistochemistry (the use of specific antibodies to stain particular molecular species in situ). Immunohistochemistry has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system. This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today, ensuring a wide audience for this book. This is the only book available that translates molecular genetics into cancer diagnosis. It provides the readers with tools necessary to perform and optimize sensitive, powerful techniques, including immunohistochemistry and fluorescence in situ hybridization, used in tumor diagnosis. Written by experts in this field, the book provides theoretical considerations as well as practical approaches to carry out effectively these techniques. It offers suggestions, tips, cautions, and guidelines to avoid artifacts and misdiagnosis. It introduces new techniques to detect genes and proteins involved in the initiation and progression of cancer. It covers the latest developments and a wide range of applications to the detection of antigens and single-copy DNA and RNA. It is written in a uniform format, each chapter includes an introduction, materials required, step-by-step detailed methods, results, discussion, and comprehensive up-to-date references.
198,00 168,30

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