Fisiologia e fisiopatologia polmonare

Dalla prefazione Questo libro è stato pubblicato per la prima volta più di quaranta anni fa ed è stato al servizio di parecchie generazioni di studenti. È stato tradotto in quindici lingue. Questa nuova undicesima edizione comprende numerose innovazioni. Prima di tutto ci sono molte più domande a scelta multipla, impostate in modo da mettere alla prova più il ragionamento che dati mnemonici. Un’ampia appendice fornisce risposte dettagliate alle domande. Ad ogni capitolo sono stati aggiunti gli obiettivi formativi e vari punti nel testo sono stati estesi per spiegarne meglio il signifi cato. Le quattordici lezioni da 50 minuti su You-Tube sono tratte dal materiale presentato in questo testo e hanno riscontrato il favore degli studenti. La URL è: http://meded.ucsd.edu/ifp/jwest/resp_phys/index.html.Nonostante queste nuove caratteristiche, gli obiettivi del libro non sono cambiati. Per prima cosa, il libro è destinato agli studenti di medicina e di materie sanitarie. Come tale sarà normalmente usato insieme a un corso di lezioni, come avviene all’UCSD. Infatti, la prima edizione è stata scritta perché ritenevo che allora non ci fosse alcun libro adatto per il primo anno del corso di fi siologia.In secondo luogo, il libro è stato scritto come un ripasso per i medici interni e per i colleghi di pneumologia, anestesiologia e medicina interna, specialmente per prepararli agli esami di abilitazione e ad altri esami. Qui le esigenze sono piuttosto diverse. Il lettore ha familiarità con l’argomento generale, ma ha bisogno di rinfrescarsi la memoria su vari argomenti e i molteplici diagrammi didattici sono particolarmente importanti.Può essere utile aggiungere qualche parola su come il libro si integri con le lezioni per gli studenti del primo anno di medicina alla UCSD. Le lezioni di fi siologia respiratoria sono solo dodici di circa 50 minuti, integrate da due esercitazioni, tre discussioni a piccoli gruppi e una sessione di revisione con l’intera classe. Le lezioni seguono strettamente i singoli capitoli del libro, con la maggior parte dei capitoli che corrispondono a una sola lezione. Le eccezioni sono il Capitolo 5, che ha due lezioni (una su scambio normale di gas, ipoventilazione e shunt; un’altra sul diffi cile argomento del rapporto tra ventilazione e perfusione); il Capitolo 6, che ha due lezioni (una sul trasporto di gas nel sangue e un’altra sull’equilibrio acido-base); il Capitolo 7, che ha due lezioni (sulla statica e sulla dinamica). Non ci sono lezioni sul Capitolo 10, “Prove di funzionalità polmonare”, perché questo non fa parte del tema centrale del corso. È incluso in parte per il suo interesse e in parte per la sua importanza per chi lavora nei laboratori di funzionalità respiratoria.Questa edizione è stata aggiornata in numerose aree, compresi scambi di gas tra sangue e tessuto, meccanica, controllo della ventilazione e sistema respiratorio sotto stress. Oltre alle risposte alle domande a scelta multipla, l’appendice B contiene le discussioni delle risposte alle domande, comprendendo le nuove domande aggiunte ai casi clinici. Sono stati fatti grandi sforzi per mantenere il libro snello, nonostante le tentazioni enormi di renderlo più corposo. Qualche volta gli studenti di medicina si chiedono se il libro è troppo superfi ciale. Non è così. Se gli specializzandi in pneumologia che iniziano il loro tirocinio in un’unità di terapia intensiva capissero completamente tutto il materiale sullo scambio dei gas e sulla meccanica respiratoria, il mondo sarebbe un posto migliore.Molti studenti e insegnanti hanno scritto per chiedere spiegazioni su enunciazioni del libro o per suggerire miglioramenti. Noi rispondiamo personalmente a ogni punto che è stato sollevato e apprezziamo molto questi contributi. John B. Westjwest@health.ucsd.eduAndrew M. Luksaluks@uw.edu

Conciliare l'utilità clinica con l'esposizione chiara dei concetti di base non è un obiettivo facile

L'insufficienza respiratoria è sempre un argomento difficile da trattare per la complessità dei meccanismi fisiopatologia del

For more than 40 years, West’s Respiratory Physiology: The Essentials has remained a critical resource for medical and allied health students learning the basics of respiratory physiology as well as an effective, quick review for residents and fellows in pulmonary medicine, critical care, anesthesiology, and internal medicine as they prepare for licensing and other exams. The eleventh edition incorporates updates in many areas including blood-tissue gas exchange, mechanics, control of ventilation and the respiratory system under stress; all designed to aid clear understanding of pulmonary physiology.   ​​Clinical vignettes with questions emphasize how the physiology described can be applied to clinical situations, reinforcing reasoning and critical thinking. More than 100 USMLE-style multiple-choice questions with full explanations test reasoning skills for comprehension and exam preparation. Additional learning objectives and chapter-opening content added to every chapter to improve understanding of key topics.   Appendices include important equations, answers to the multiple-choice questions, and discussions of the answers to the end-of-chapter clinical vignettes. Online resources include animations that expand on and clarify challenging topics and an interactive question bank to allow self-testing and exam review. eBook available for purchase. Fast, smart, and convenient, today’s eBooks can transform learning. These interactive, fully searchable tools offer 24/7 access on multiple devices, the ability to highlight and share notes, and more.

Nunn's Applied Respiratory Physiology, Ninth Edition, is your concise, one-stop guide to all aspects of respiratory physiology in health, disease, and in the many physiologically challenging situations and environments into which humans take themselves - coverage is from basic science to clinical applications. Trusted for over 50 years, this most comprehensive single volume on respiratory physiology will prove invaluable to those in training or preparing for examinations in anaesthesia, intensive care, respiratory medicine or thoracic surgery - as well as an essential quick reference for physiologists and the range of practitioners requiring ready access to current knowledge in this field. Now fully revised and updated, this ninth edition includes a larger page format for improved clarity, as well as full access to the complete, downloadable eBook version. This incorporates BONUS chapters, handy topic summaries, interactive self-assessment material and a NEW series of expert lectures on key topics. The result is a more flexible, engaging and complete resource than ever before. Enhancements to this edition include: A new dedicated chapter on obesity - covering the effects of this global challenge on the physiology of the respiratory system in health and disease, in both adults and children Expanded coverage of the adverse effects of hyperoxia - including the physiology of the now popular technique of high-flow nasal therapy A revised section on air pollution - reflecting the growing importance and understanding of the impact of pollution on the lungs and other body systems, along with the latest worldwide guidelines Detailed coverage of artificial ventilation during general anaesthesia - covering post-operative respiratory complications and the physiological basis of current best-practice for optimizing ventilation Print comes with enhanced eBook - includes access to the complete, fully searchable text, PLUS: bonus chapters handy chapter summaries interactive self-assessment material a NEW series of 25 expert lectures focusing on the most essential topics in respiratory physiology

The seventh edition of the most authoritative and comprehensive book published on lung function, now completely revised and restructured Lung function assessment is the central pillar of respiratory diagnosis. Most hospitals have lung function laboratories where patients are tested with a variety of physiological methods. The tests and techniques used are specialized and utilize the expertise of respiratory physicians, physiologists, and technicians. This new edition of the classic text on lung function is a theoretical textbook and practical manual in one that gives a comprehensive account of lung function and its assessment in healthy persons and those with all types of respiratory disorder, against a background of respiratory, exercise, and environmental physiology. It incorporates the technical and methodological recommendations for lung function testing of the American Thoracic Society and European Respiratory Society. Cotes' Lung Function, 7th Edition is filled with chapters covering respiratory surveys, respiratory muscles, neonatal assessment, exercise, sleep, high altitude, hyperbaria, the effects of cold and heat, respirable dusts, fumes and vapors, anesthesia, surgery, and respiratory rehabilitation. It also offers a compendium of lung function in selected individual diseases and is filled with more diagrams and illustrative cases than previous editions. The only text to cover lung function assessment from first principles including methodology, reference values, and interpretation Completely re-written in a contemporary style—includes user-friendly equations and more diagrams Covers the latest advances in the treatment of lung function, including a stronger clinical and practical bias and more on new techniques and equipment Keeps mathematical treatments to a minimum Cotes' Lung Function is an ideal guide for respiratory physicians and surgeons, staff of lung function laboratories, and others who have a professional interest in the function of the lungs at rest or on exercise and how it may be assessed. Physiologists, anthropologists, pediatricians, anesthetists, occupational physicians, explorers, epidemiologists, and respiratory nurses should also find the book useful.

Il volume, organizzato in 8 sezioni e 34 capitoli, tratta la clinica delle malattie respiratorie, i rapporti con le malattie concomitanti e i relativi aspetti organizzativi e normativi.

Systematically solve tough diagnostic challenges in pulmonary pathology with this new title in the Differential Diagnoses in Surgical Pathology series. This practical reference uses select images of clinical and pathological findings, together with succinct, expert instructions, to guide you through the decision-making process by distinguishing between commonly confused pulmonary lesions. By presenting material according to the way pathologists actually work, this user-friendly volume helps you quickly differentiate entities that have overlapping morphologic features in both neoplastic and non-neoplastic lung pathology. Key Features: * Presents more than 90 differential diagnoses in pulmonary pathology side by side for easy comparison, including the most common entities as well as selected rarer diseases.* Provides concise, bulleted summaries of clinical and pathological findings and relevant pictorial examples on the corresponding pages.* Features high-quality images of similar-looking lesions side by side for easy comparison.* Helps you accurately and efficiently answer many everyday questions such as, "Is this UIP or NSIP?" and "Is this malignant mesothelioma or reactive mesothelial hyperplasia?" * Ideal for practicing pathologists, pathologists in training, residents, and medical students.Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like: *Complete content with enhanced navigation *Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web*Cross-linked pages, references, and more for easy navigation*Highlighting tool for easier reference of key content throughout the text* Ability to take and share notes with friends and colleagues*Quick reference tabbing to save your favorite content for future use

Concise, portable, and user-friendly, The Washington Manual(R) Pulmonology Subspecialty Consult, 2nd Edition, provides quick access to the essential information needed to evaluate patients on a subspecialty consult service. This edition offers state-of-the-art content on the diagnosis, investigation, and treatment of common acute and chronic lung diseases, including coverage of advancing technologies and therapeutics. Ideal for fellows, residents, and medical students rotating on pulmonology subspecialty services, the manual is also useful as a first-line resource for internists and other primary care providers. Key Features:*Thoroughly revised to include expanded diagnostic testing and therapies for pulmonary diseases.* A reorganized, templated format throughout ensures that you can find what you need quickly and easily.*Comprehensive coverage of asthma, COPD, interstitial lung disease, pulmonary hypertension, cystic fibrosis, pulmonary infections, lung transplantation, sleep-disordered breathing, and other common pulmonary conditions provides practical clinical information to diagnose and treat a variety of patients.* Symptoms, signs, and problems encountered in daily practice are presented in a quick-reference bulleted format.*Updated references are provided for readers who would like additional information on a particular topic.* Written by fellows and junior faculty from the Washington University School of Medicine in St. Louis to effectively address real-life clinical experiences.Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like: *Complete content with enhanced navigation*Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web*Cross-linked pages, references, and more for easy navigation*Highlighting tool for easier reference of key content throughout the text* Ability to take and share notes with friends and colleagues*Quick reference tabbing to save your favorite content for future use

The Second Edition of this book was the Winner of the First Prize (Respiratory Category) at the British Medical Association Medical Book Awards. Textbook of Pleural Diseases is a comprehensive reference that covers both the basic and clinical science on pleural diseases. Building on the highly respected previous editions, it includes a detailed basic science section for enhanced understanding of both the physiological and pathophysiological mechanisms that underpin diseases of the pleura. The clinical sections are written in a uniform style and include the definition, epidemiology, etiology, pathogenesis, clinical presentation, investigations, treatments, and possible complications for various pleural diseases. Other clinical chapters discuss both familiar and less common disease aspects. Five new chapters have been added covering new technologies in the clinical management of pleural diseases, procedural complications and safety measures, and the setting up of a pleural practice. The remaining chapters have been substantially updated. About a third of the 50 chapters in this edition are written by new expert authors providing a fresh view and reflecting the expansion of knowledge in the field. Each chapter includes a bullet-point summary, and published management guidelines are included where relevant. Also included is a "Key Points" section in each chapter that highlights patient management, making this an indispensable reference for pulmonary physicians, internists, thoracic surgeons and trainees worldwide.

Get a deeper understanding of respiratory disease with Clinical Manifestations and Assessment of Respiratory Disease, 7th Edition. This popular, full-color text provides all the necessary tools you need to learn how to gather clinical data, formulate assessments, make objective evaluations, identify desired outcomes, design a safe and effective treatment plan, and document all the steps involved. Using easy-to-follow language and relevant clinical scenarios, this text gives readers a firm understanding of why certain treatment modalities are applied. And with a new chapter on respiratory failure and mechanical ventilation protocol, new information on electronic charting, and numerous updates in treatment and assessment added to nearly all the chapters, this new edition ensures you will be well-versed in all of the new issues affecting respiratory therapy.

Respiratory Care Exam Review: Review for the Entry Level and Advanced Exams, 3rd Edition, readies students with review materials for both the CRT and RRT exams! The material is presented in an outline format for efficient studying with special boxes included in the chapter to highlight important information that is often included in the exam. The accompanying Evolve Web site provides practice exams for both the advanced and entry level exams to familiarize test-takers with the computerized exam format. Clinical simulations for the RRT are also included to give students the opportunity to practice this very difficult portion of the registry exam. New content has been added to the 3rd edition, including the latest updates to the NBRC content outlines implemented in 2009 and 2010. Be fully prepared with this comprehensive text!