The treatment of melanoma
Paolo Antonio Ascierto
editore: Minerva Medica
This book provides an overview of melanoma skin cancer and illustrates the most recent advances in the field of its clinical management. Today, thanks to new treatments like targeted therapies and immunotherapies, about 50% of metastatic patients can be cured and healed. Moreover, recently, such treatments have proven effective in the adjuvant setting by reducing the risk of disease progression and the mortality rate by 30-40%. Melanoma management represents a model for immuno-oncology, and starting from the experiences made in this field, today immune checkpoint inhibitors can also be successfully used to treat other neoplasms. However, in spite of the good results achieved, mortality rates are still high. For this reason, we still need to gain a better understanding of the mechanisms underlying primary and acquired resistance, and to find ways to extend the long-term benefits that have been recently achieved in resistant patients.
Gloriana Assalti, Cinzia Tafuto
editore: Acta Medica Edizioni
Tra i compiti della medicina estetica c’è la “cura del futile” ovvero ciò che esula dalla terapia psicofisica e che valorizza l’immagine della persona, articolando le prestazioni in virtù di un visibile riscontro e di una piena partecipazione del malato, tale da spostare la sua attenzione dalla malattia.La funzione principale della medicina estetica nei confronti del paziente oncologico consiste nel prevenire i danni cutanei causati dalla tossicità dei farmaci e i danni psicologici derivanti dalla compromissione della sua immagine corporea.Il suo obiettivo pertanto è cercare di tendere all’essere attraverso l’apparire, modificare l’aspetto esterno al fine di modulare quello più intimo e profondo stimolando fiducia e coraggio.
A Surgical Perspective
editore: Thieme Medical Publishers Inc
The treatment of skin cancer has become an increasingly multispecialty practice. Ongoing surgical and postsurgical advances and emergent factors that predispose patients to these tumors have changed the treatment paradigm. Having a keen understanding of diagnostic, surgical, and nonsurgical treatment options is key to identifying, treating, or referring patients with potential cutaneous malignancies. While Brian R. Gastman's Cutaneous Malignancies: A Surgical Perspective is the first of its kind to emphasize surgical management of skin cancer, several sections are devoted to systemic nonsurgical therapies affecting patient care and surgical intervention. Topics encompassed include prevention, diagnosis, medication management, appropriate margin size, reconstruction methods, and the importance of stellar dermatopathology. Key Highlights The role of Mohs micrographic surgery and radiation in skin cancer treatment Treatment approaches for the two most common forms of skin cancer respectively, basal cell carcinoma and squamous cell carcinoma Surgical treatment of cutaneous malignant melanoma and other high-risk malignancies Clinical insights on completion lymphadenectomy and sentinel node biopsy for melanoma, two topics rarely addressed in context with skin cancer Diagnosis and treatment of rare malignancies including Merkel cell carcinoma, dermatofibrosarcoma protuberans, cutaneous angiosarcoma, and cutaneous leiomyosarcoma More than 400 high-quality illustrations further delineate surgical modalities Edited by an esteemed dual board certified plastic surgeon and otolaryngologist, this definitive book is the most complete guide to surgical management of skin cancer. It is essential reading for plastic surgeons, dermatologists, otolaryngologists, and all clinicians who treat or refer patients with suspected skin cancer.
Cancer of the Skin
Cancer: Principles & Practice of Oncology
Steven A. Rosenberg, Theodore S. Lawrencee altri
editore: Lippincott Williams and Wilkins
"A derivative of Cancer: principles & practice of oncology, 10th edition."
The Illustrated Guide
editore: John Wiley & Sons Inc
Skin lymphomas are relatively rare but potentially fatal. They can easily be misdiagnosed as benign skin diseases. Dermatologists and pathologists need to have a good understanding of the clinical presentations and the pathological correlates of this challenging disease to ensure the correct diagnosis and most appropriate treatment is provided. Skin Lymphoma: The Illustrated Guide is a full-color illustrated text and atlas that combines pathology with clinical features and treatment. Jam-packed with pictures that illustrate key diagnostic points and supplemented by teaching cases to highlight effective decision making. It includes all newly identified entities and provides pointers on how to differentiate these. In addition, it also covers all inflammatory conditions that may simulate skin lymphomas (cutaneous pseudolymphomas). Skin Lymphoma: The Illustrated Guide provides: clinical and pathological guidance on diagnosis of skin lymphomas; clear illustrations to aid visual recognition * Nomenclature according to WHO/EORTC classifications; and, cases to enhance the scope for teaching and learning. This fully refreshed fourth edition continues to provide the clinical excellence that has helped a generation of dermatologists and dermatopathologists to effectively diagnose skin lymphoma.
Dermatologic Principles and Practice in Oncology
Conditions of the Skin, Hair, and Nails in Cancer Patients
Mario E. Lacouture
editore: Wiley-Blackwell (an imprint of John Wiley & Sons Ltd)
This is the first book to focus on frequent and frequently disabling side effects involving the skin, hair, and nails in cancer patients. It provides detailed descriptions of mechanism-of-action in all current oncology drugs and the clinical presentation and mechanisms underlying their dermatologic side effects, alongside carefully presented treatment recommendations, allowing physicians to significantly enhance their care of patients with cancer. Whereas existing oncology and dermatology textbooks only briefly deal with this topic, this resource offers dermatologists and other practitioners a focused perspective on cancer-related skin conditions.
A Practical Approach
Alfonso Baldi, Enrico P. Spugninie altri
editore: Humana Press Inc.
Skin Cancer: A Practical Approach presents a comprehensive and up to date overview on skin cancer. With an emphasis on practical aspects that will set the basis for guidelines of treatment, the volume presents different diagnostic tools to help physicians obtain the proper diagnosis. Written by a worldwide base of experts selected on their recognized expertise on the different themes discussed, Skin Cancer: A Practical Approach is a valuable resource for investigators in the field of skin cancer, including pathologists, medical and surgical oncologists, dermatologists, general surgeons, and veterinary oncologists
Cancer of the Skin
Clay J. Cockerell, Darrell S. Rigele altri
"Cancer of the Skin", edited by Drs. Rigel, Robinson, Ross, Friedman, Cockerell, Lim, Stockfleth, and Kirkwood, is your complete, multimedia guide to early diagnosis and effective medical and surgical treatment of melanoma and other skin cancers. Thoroughly updated with 11 new chapters, this broad-based, comprehensive reference provides you with the latest information on clinical genetics and genomics of skin cancer, targeted therapy for melanoma, the Vitamin D debate concerning the risks and benefits of sun exposure, and other timely topics. A new, multi-disciplinary team of contributors and editors comprised of leading experts in this field offers truly diverse perspectives and worldwide best practices.
Biopsy Interpretation of the Skin
Primary Non-lymphoid Neoplasms of the Skin
A. Neil Crowson, Cynthia M. Magroe altri
editore: Lippincott Williams and Wilkins
This new volume of the "Biopsy Interpretation Series" is a practical, superbly illustrated reference on the primary non-lymphoid neoplasms of the skin. The book offers guidelines on how and when to biopsy the skin and then discusses benign melanocytic proliferations, precursor lesions to melanoma, and melanomas. Also included are discussions of basal cell carcinoma, squamous cell carcinoma and its precursors, benign and malignant adnexal neoplasms, and soft tissue neoplasms of the skin and superficial subcutis. A major highlight of the book is the extensive discussion of differential diagnostic considerations and their separation from the main diagnostic entities under consideration. The book features nearly 300 full-color images. A companion Website will provide 400 additional figures, plus a test bank that is ideal for board exam preparation.
Diagnostic Atlas of Melanocytic Pathology
Expert Consult: Online and Print
J. Eduardo Calonje, Phillip H. McKee
Diagnose any benign, premalignant, or malignant melanocytic lesion with over 1000 high-quality color images in this practical, easy-to-use reference. Drs. McKee and Calonje - editors of the best-selling dermatopathology reference "Pathology of the Skin, 3rd Edition" - present their expert knowledge by including diagnostic pearls and pitfalls throughout the text for quick, at-a-glance guidance. Correlate clinical and pathologic findings to produce a more accurate diagnosis from discussions of the clinical manifestations of melanocytic lesions. The format of the text makes this book an excellent resource for bench work and reviewing for exams. Expert Consult functionality allows you to access the entire contents of the book online, from any internet connection.
WHO Classification Pathology & Genetics Skin Tumours
World Health Organization Classification of Tumours
LeBoit, P. E. , Burg, G. , Weedon, D. , Sarasin, A.
Il melanoma «difficile» in dermoscopia. Miniatlante
M. A. Pizzichetta
editore: Minerva Medica
L'utilizzo della dermoscopia come ausilio diagnostico non invasivo nel difficile e strategico settore della diagnosi precoce del melanoma ha rappresentato una delle più importanti novità nella dermatologia dell'ultimo decennio. Questo miniatlante, promosso e realizzato nell'ambito di un progetto multicentrico della Associazione Italiana di Diagnostica non Invasiva in Dermatologia, prende in rassegna i melanomi "difficili", cioè quei casi non frequentissimi, ma neppure così eccezionali nella pratica clinica, nei quali l'esame dermoscopico da solo può non essere sufficiente a formulare una diagnosi corretta.
Gunter Burg, Werner Kempf
editore: Informa Healthcare
Based on extensive clinical, histological, and experimental studies, this guide serves as an authoritative source of information on the epidemiology, etiology, pathogenesis, diagnosis, and treatment of cutaneous lymphomas-reflecting the state-of-the-art in the field of cutaneous lymphomas-presented in the context of the brand-new WHO/EORTC-consensus-classification.
An Illustrated Guide to Skin Lymphoma
Herr Helmut Kerl, Kevin Gattere altri
editore: Blackwell Publishing Ltd
Skin lymphomas are relatively rare. They may arise in the skin itself and as a by-product of HIV infection, or may arise elsewhere as a result of Hodgkin's disease, B cell lymphomas or leukaemia. Whatever the cause, they can easily be overlooked as psoriasis or dermatitis. Diagnosis of skin lymphoma is difficult and making the wrong diagnosis can prove fatal. Consequently, those in training in dermatology and pathology need to have a good understanding of the clinical presentations and the pathological correlates of this challenging disease. An Illustrated Guide to Skin Lymphoma is a beautiful full-colour illustrated text and atlas that combines pathology with clinical features and treatment. This second edition includes the latest classification systems for cutaneous lymphomas as well as brand new chapters and an expanded section on treatment.
Balch, C. M. , Houghto, A. N. , Sober, A. J. , Soong, S.
editore: Quality Medical Publishing
Biologically Targeted Therapeutics
E. C. Borden
editore: Humana Press Inc.
Ernest C. Borden, MD, has assembled a multidisciplinary team of established and emerging leaders to detail the clinical problems and factors influencing the therapeutic deployment of these biologicals. The contributors focus on providing the rationale and background for translating the many promising biologically targeted therapies via clinical trials into effective new therapies. Among the interventional agents treated are: cytokines, monoclonal antibodies, targeted inhibitors, cellular therapies, and angiogenesis inhibitors. Special attention is given to adjuvant therapies for melanoma in patients staged as being at high risk for recurrence. These include interferons, vaccines aimed at stimulating T cell response, and therapies targeted at abnormal melanoma cell proliferative signaling and angiogenesis inhibitors. Among the cutting-edge therapies discussed are novel cytokines that influence dendritic NK and T cell function, an allogenic cellular extract vaccine, and new targets (Nf-kB and IL-8) for anti-angiogenesis therapies.
Arthur J. Sober, Frank G. Haluska
editore: B.C. Decker Inc
Part of the "American Cancer Society's Atlas of Clinical Oncology" series, this full-color atlas offers a comprehensive visual guide to diagnosis, management, and post-treatment care for all stages of skin cancer.
editore: McGraw-Hill Medical
The ultimate all-in-one guide to diagnosing and treating skin cancer A Doody's Core Title ESSENTIAL PURCHASE! 4 STAR DOODY'S REVIEW! "This excellent comprehensive book covers all types of skin cancer, their clinical presentation, the genetic alterations leading to particular tumors, and treatment. The clinical color photographs for the most part are of fine quality. The histology is shown side by side with the clinical findings. Shaded summary boxes highlight the salient points for those who wish a quick read through the book...Everyone will enjoy the thorough coverage of the diagnosis and management of skin cancer in this book. I highly recommend it be purchased by any physician caring for patients with skin cancer. The abundant illustrations are of high quality."--Doody's Review Service "This all-inclusive textbook contains the most comprehensive, up-to-date and detailed information on any topic related to skin cancer...It could serve as the main resource for any physician for years to come." --Perry Robins, MD, President, Skin Cancer Foundation (from the foreword) Comprehensive in scope, yet precise in its approach, this superbly illustrated text is a must-have clinical companion for any dermatology practice. Skin Cancer carefully takes you through every important step in the diagnosis and clinical management of skin cancer conditions. Skin Cancer begins with an incisive discussion of both normal and aging skin, and the incidences and causes of skin cancer. Next, you'll get a thorough look at all types of skin cancer--followed by a section on treating cancer in various patient populations, including non-white populations, children, and pregnant women. The book concludes with in-depth sections on skin cancer prevention--covering critical topics such as skin cancer vaccines and chemoprevention of skin cancer--in addition to the medicolegal and economic issues related to skin cancer. Features: The complete A-to-Z guide to skin cancer, offering a clear understanding of skin cancer epidemiology, pathophysiology, diagnosis, treatment, future directions, and medicolegal and psychosocial aspects More than 450 illustrations State-of-the-art coverage of biopsy techniques, dermoscopy and mole mapping, surgical excision, reconstructive surgery of eye lid cancers and skin cancer defects, and more Consistent outlines of chapters within a section that summarize chapter material Key points that introduce the start of each major section within a chapter Numerous easy-to-use tables and boxes