Gastroenterologia

Diverse patologie umane partono da un intestino poco efficiente. Ma cosa rende inefficiente l'intestino? Bisogna rivalutare i rapporti tra cibo e salute. Tre milioni di italiani e venti milioni di statunitensi soffrono di sensibilità al glutine, sindrome simile ma allo stesso tempo diversa dalla celiachia. Dalla sensibilità al glutine scaturiscono patologie diverse, in funzione del polimorfismo genetico dei soggetti e dell'ambiente in cui essi vivono. Aumentando le nostre conoscenze sulle interazioni tra cibo, abitudini alimentari, genomica e ambiente è possibile effettuare una prevenzione e/o terapia migliore. È iniziata l'era dell'epigenetica mentre il dogma del determinismo genetico si avvia al tramonto. Nell'intestino è concentrato il 70% del sistema immunitario il quale ha il compito di uccidere virus, batteri, parassiti, eliminare le cellule tumorali. E' lungo circa 8 metri e permette l'assorbimento dei nutrienti e dell'acqua. La nostra difesa e la nostra energia vengono dall'intestino.

Sleisenger e Fordtran Malattie gastrointestinali ed epatiche è il riferimento essenziale per gli specialisti di gastroenterologia ed epatologia. Giunto alla sua decima edizione, il volume è universalmente riconosciuto come una fonte indispensabile per lo studio dei disturbi gastroenterologici ed epatici. Centinaia di autori di fama mondiale hanno collaborato alla sua stesura, garantendone l'aggiornamento con le più recenti tecniche, tecnologie e trattamenti e assicurando la completezza e l'autorevolezza dei contenuti. Il testo ha un orientamento clinico e i capitoli presentano sempre la medesima struttura (epidemiologia, eziologia, patologia, fisiopatologia, caratteristiche cliniche, diagnosi, diagnosi differenziale, trattamento e prognosi) così da rendere facile la consultazione e l'individuazione delle informazioni. Tra le novità di questa edizione vi sono argomenti di crescente interesse come il microbiota enterico e i probiotici, il trapianto di microbiota fecale, la colite da Clostridium difficile e i disturbi gastrointestinali fittizi. Sono inoltre affrontati i più recenti avanzamenti nella diagnosi e trattamento dei pazienti con disturbi epatici di cui sono trattate anche le strategie post-trattamento e la gestione delle complicanze. Gli innumerevoli progressi avvenuti negli ultimi anni nel campo della medicina trovano spazio nella trattazione, ad esempio, degli aspetti cellulari, molecolari e genetici alla base della fisiologia e fisiopatologia delle malattie gastrointestinali e del fegato; dei nuovi test e procedure diagnostiche, delle tecniche di endoscopia sia diagnostica che terapeutica, dello sviluppo di nuove classi di farmaci che mirano a risolvere condizioni precedentemente prive di trattamento e dell'utilizzo della chirurgia laparoscopica in molti disturbi gastroenterici.

L'idea che la salute e la malattia dipendano in gran parte dalle condizioni dell'intestino non è nuova. L'intestino è l'organo responsabile del primo contatto con le sostanze nutritive che ingeriamo ogni giorno, quindi non stupisce che un suo cattivo funzionamento possa avere un impatto negativo sul nostro benessere. Nuovissima è invece la scoperta che la salute non dipende solo dalle condizioni delle cellule umane, ma anche dallo stato in cui versa l'enorme popolazione di batteri che vivono nel nostro corpo e in particolare proprio nell'intestino. Oggi sappiamo che questi microscopici coinquilini che dividono con noi la loro sorte sono responsabili di una quantità di funzioni fondamentali per il raggiungimento e il mantenimento di un adeguato stato di benessere. Purtroppo lo stile di vita occidentale predispone allo sviluppo di disbiosi, ovvero all'impoverimento progressivo della flora batterica intestinale, e si ritiene che questa condizione sia collegata a un aumento di incidenza delle cosiddette "malattie del progresso". Ma si sa anche in che modo le disbiosi possano essere prevenute, diagnosticate e corrette. Questo libro si propone di svelare ai lettori i segreti del proprio intestino per permettere loro di ottimizzare il metabolismo, la performance fisiologica e il sistema immunitario, allo scopo di prevenire le principali malattie del secolo e vivere meglio, più sani e, possibilmente, più a lungo.

Interventional Inflammatory Bowel Diseases: Endoscopic Management and Treatment of Complications covers the preparation, principle, techniques, and damage control of complications in endoscopic therapy, providing the ultimate guidance in endoscopic management of IBD. With contributions from a panel of international leading experts in the field, perspectives are included from GI pathologists, GI radiologists, gastroenterologists, advanced endoscopists, IBD specialists and colorectal surgeons. Recommendations from experts are also included within each chapter. By bridging medical and surgical treatment modalities for IBD, this is the perfect reference for GI researchers, medical students, therapeutic GI endoscopists, IBD specialists, surgeons and advanced health care providers.

This revised and updated second edition of the popular and comprehensive guide to the study of gastroenterology The revised second edition of Essentials of Gastroenterology provides a highly practical and concise guide to gastroenterology. The text covers every major disorder likely to be encountered during both GI training and in clinical practice. It also offers a handbook for preparing for Board examinations (e.g., USMLE and Internal Medicine Board examinations) as well as a handy clinical consultation tool. Fully updated to reflect the latest scientific information and practice guidelines, each section of the book covers a specific area of the gastroenterology tract and follows a standard outline: general information, normal physiology, etiology and pathophysiology, clinical presentation, diagnosis, differential diagnosis, complications, prognosis, and treatment. The text provides easy-to-assimilate information on each disorder and includes the key facts, concise, bulleted paragraphs, and a structure that lends itself to accessibility and point-of-care use in a busy clinical setting. In addition, Internal Medicine Board-style multiple choice questions allow users to self-assess their knowledge, a photo gallery provides a great visual element, and clinical cases throughout allow readers to identify with real-life clinical scenarios. Essentials of Gastroenterology is the hands-on guide that: Covers the whole of gastroenterology in one highly practical volume Presents updated pedagogic features to help achieve rapid clinical understanding, such as case studies, practice points, key weblinks and potential pitfalls boxes Includes more than 100 Internal Medicine Board-style multiple choice questions ideal for self-assessment Contains comparison of major society (BSG, ASG, ACG, UEGF, etc.) guidelines for all main GI conditions Designed for us by gastroenterologists and GI trainees, Essentials of Gastroenterology is therevised and improved edition of the popular manual that is filled with up-to-date information on all the GI disorders. Trainees will learn the essentials of their specialty, as well as providing the seasoned gastroenterologist with a useful refresher tool.

With extensively revised content and an expanded contributor list of experts, Fenoglio-Preiser's Gastrointestinal Pathology, Fourth Edition keeps you current in this fast-changing field. This highly regarded text remains your go-to reference on gastrointestinal pathology, with coverage of everything from anatomy, physiology, and histology to the full spectrum of congenital disorders, structural alterations, diseases, injuries, and other entities. This comprehensive reference is an ideal resource for pathologists, radiologists, gastroenterologists, and others interested in gastrointestinal diseases. Key Features:* Contains extensively revised and updated content throughout, while maintaining the same practical, easy-to-use format as the previous edition.* Covers benign and malignant gastrointestinal diseases not often included in other texts, as well as in-depth discussions of pathophysiologic processes and molecular mechanisms wherever possible.* Features more than 3,000 high-quality illustrations, including gross and microscopic photographs (many new to this edition), electron micrographs, radiographs, and line drawings.* Includes separate chapters on hereditary polyposis, cancer syndromes, motility disorders, and inflammatory bowel disease, as well as neuroendocrine, hematopoeitic, and mesenchymal neoplasms.* Integrates pathologic analyses of specimens with anatomic, clinical, radiologic, pathophysiologic, and microbiologic information to give you a clear understanding of each disease process.* Serves as a comprehensive resource for the pathologist evaluating biopsies, cytologic, or resection specimens from all GI sites.Your book purchase includes a complimentary download of the enhanced eBook for iOS, Android, PC & Mac. Take advantage of these practical features that will improve your eBook experience:* The ability to download the eBook on multiple devices at one time - providing a seamless reading experience online or offline* Powerful search tools and smart navigation cross-links that allow you to search within this book, or across your entire library of VitalSource eBooks* Multiple viewing options that enable you to scale images and text to any size without losing page clarity as well as responsive design* The ability to highlight text and add notes with one click

Previous Edition won First Prize in the Gastroenterology category of the 2008 BMA Medical Book Competition High-resolution endoscopy and narrowband imaging have revolutionized the field. Edited by a gastroenterologist with a reputation for delivering outstanding material, this new edition of an award-winning atlas provides you with an outstanding collection of images, videos and expert diagnostic guidance to enhance your decision making. To accelerate your learning, Dr. Cohen offers more than 2000 endoscopic images, emphasizing conditions for which NBI is particularly useful such as finding dysplasia in Barrett s mucosa, and diagnosing adenomatous colon polyps and providing exceptional preparation for the future of endoscopy practice, with a broad new look at normal and abnormal findings throughout the GI tract. The book is divided into three main parts: The basics of NBI Clinical applications of NBI Atlas of 2000 color images, broken into sections on the pharynx and esophagus, stomach, small intestine, and colon, including correlating histopathology and multiple examples of key pathologies The accompanying website features more than 80 video clips containing over 3 hours of annotated video, to give you a complete sense of how HRE and NBI work and look in real time, including during therapeutic procedures. All of the over 1000 new images appear in much brighter color, reflecting the advance in scope technology since the first edition. New chapters have been added to present the data supporting increased use of NBI in optical diagnosis and in the context of therapeutic procedures. For the first time, brilliant images of the bile duct and pancreas are included as the imaging revolution has expanded to reach these new locations. This spectacular new imaging modality promises to enhance endoscopic decision making in real time, facilitate therapeutic maneuvers, make tissue sampling more precise and make resection of mucosal neoplasia more complete. Expertly guiding you through the latest advances, this book facilitates your mastery of the field, and provides an up-to-date reference for gastroenterologists and endoscopists to improve their practice. www.wiley.com/go/gastroenterology

Gastroenterology and Hepatology - with all the authority of Harrison's Featuring a superb compilation of chapters related to gastroenterology and hepatology derived from Harrison's Principles of Internal Medicine, Nineteenth Edition (including content from the acclaimed Harrison's DVD, now available here in print), this concise, full-color clinical companion delivers the latest knowledge in the field backed by the scientific rigor and authority that have defined Harrison's. You will find 63 chapters from more than 80 renowned editors and contributors in a carry-anywhere presentation that is ideal for the classroom, clinic, ward, or exam/certification preparation. FEATURES * Coverage includes: cardinal manifestations of disease, evaluation of the patient, disorders of the alimentary tract, infections of the alimentary tract, disorders of the liver and biliary tree, liver transplantation, disorders of the pancreas, neoplastic diseases of the gastrointestinal system, nutrition, and obesity and eating disorders * Reflects the most current advances in genetics, cell biology, pathophysiology, and treatment * Integration of pathophysiology with clinical management * High-yield board review questions make this text ideal for keeping current and preparing for the boards * Helpful appendix of laboratory values of clinical importance

Master the content you need to know for the Core Exam module for gastrointestinal imaging! This unique, image-rich resource is an excellent tool for self-assessment and exam prep, whether you're studying for the Core Exam or MOC. More than 300 questions, answers, and explanations accompany hundreds of high-quality images, in a format that mimics the Core Exam. Gastrointestinal Imaging: A Core Review tests your knowledge of every aspect of this challenging and rewarding subspecialty, covering the wide variety of organs, the diversity of diseases and treatments, and the full spectrum of available imaging modalities. Key Features *Hundreds of high-quality images reflect what you can expect to see on the image-rich Coreexam.*Multiple-choice questions and extended matching questions have corresponding answers with explanations of not only why one answer is correct, but also why other options are incorrect.*Questions are divided according to the Core Exam Study Guide, so you can work on particular topics as needed.* Answers include brief discussions of differential diagnosis and high-yield tables for additional quick review.* References are provided for every question, helping you further your knowledge when you want to delve more deeply into a particular topic.*An ideal reference and review tool for residents, fellows, practicing radiologists, and those preparing for Maintenance of Certification.Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like:*Complete content with enhanced navigation*Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web*Cross-linked pages, references, and more for easy navigation*Highlighting tool for easier reference of key content throughout the text* Ability to take and share notes with friends and colleagues*Quick reference tabbing to save your favorite content for future use

Master the key concepts that are critical to the practice of gastrointestinal radiology! Covering everything residents need to know for clinical rotations, this efficient learning tool puts indispensable information at your fingertips in a practical, high-yield format. Learning objectives, summary points, differential diagnosis tables, and multiple-choice questions facilitate effective study. More than 800 superb illustrations highlight the "essentials" of the field - information that is vital to understanding the wide variety of pathologies seen in gastrointestinal imaging. Key Features *Detailed imaging studies, including radiography, fluoroscopy, cross-sectional imaging modalities, barium studies, MR imaging, and more accompany concise guidance on the primary pathologies that affect the GI tract.*Recent advances in radiology are discussed by a team of well-known experts in the field, keeping you up to date with radiology's role in early detection, diagnosis, triage, and treatment.* Coverage of every essential area of gastrointestinal radiology, including barium studies, esophagus, stomach, duodenum and small bowel, large bowel, appendix, peritoneum, liver, gall bladder and bile ducts, pancreas, and spleen.*Learning objectives in each chapter help you focus your study, references are provided for further in-depth learning, and a complete self-assessment exam is provided at the end of the book.*Approximately 200 multiple-choice questions, all consistent with current certification exams, reinforce important concepts and facilitate self-assessment Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like:*Complete content with enhanced navigation*Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web*Cross-linked pages, references, and more for easy navigation*Highlighting tool for easier reference of key content throughout the text* Ability to take and share notes with friends and colleagues*Quick reference tabbing to save your favorite content for future use