The treatment of melanoma
Paolo Antonio Ascierto
editore: Minerva Medica
This book provides an overview of melanoma skin cancer and illustrates the most recent advances in the field of its clinical management. Today, thanks to new treatments like targeted therapies and immunotherapies, about 50% of metastatic patients can be cured and healed. Moreover, recently, such treatments have proven effective in the adjuvant setting by reducing the risk of disease progression and the mortality rate by 30-40%. Melanoma management represents a model for immuno-oncology, and starting from the experiences made in this field, today immune checkpoint inhibitors can also be successfully used to treat other neoplasms. However, in spite of the good results achieved, mortality rates are still high. For this reason, we still need to gain a better understanding of the mechanisms underlying primary and acquired resistance, and to find ways to extend the long-term benefits that have been recently achieved in resistant patients.
Diagnostic Pathology: Neoplastic Dermatopathology
David S. Cassarino
editore: Elsevier - Health Sciences Division
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of neoplastic dermatopathology, it incorporates the most recent clinical, pathological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, Diagnostic Pathology: Neoplastic Dermatopathology is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource. Covers the broad array of cutaneous neoplasms and their differential diagnoses in a concise, practical, and richly illustrated format Analyzes hundreds of diagnoses, each of which include critical diagnostic information such as definitions, epidemiology, clinical presentation, macro- and microscopic features, differential diagnoses, and pathologic interpretation pearls Features thorough updates throughout, including new information from molecular pathology studies that describe multiple mutations in different cutaneous tumors, and updated staging details for melanoma, cutaneous lymphoma, and other tumors Addresses recent advances in molecular pathology-new diagnostic, immunohistochemical, molecular, and genetic techniques used for diagnosis, as well as updated reportable staging details for several new diagnoses and identification of newly recognized tumors Details the expanded scope of knowledge available from the 2018 update to the World Health Organization and European Organization for Research and Treatment of Cancer (WHO-EORTC) Includes more than 2,900 carefully annotated photographs, images, and illustrations plus nearly 1,000 additional digital-only images to help practicing and in-training pathologists reach a confident diagnosis Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices
Gloriana Assalti, Cinzia Tafuto
editore: Acta Medica Edizioni
Tra i compiti della medicina estetica c’è la “cura del futile” ovvero ciò che esula dalla terapia psicofisica e che valorizza l’immagine della persona, articolando le prestazioni in virtù di un visibile riscontro e di una piena partecipazione del malato, tale da spostare la sua attenzione dalla malattia.La funzione principale della medicina estetica nei confronti del paziente oncologico consiste nel prevenire i danni cutanei causati dalla tossicità dei farmaci e i danni psicologici derivanti dalla compromissione della sua immagine corporea.Il suo obiettivo pertanto è cercare di tendere all’essere attraverso l’apparire, modificare l’aspetto esterno al fine di modulare quello più intimo e profondo stimolando fiducia e coraggio.
Atlante di dermoscopia
G. Argenziano, E. Moscarellae altri
editore: Piccin-Nuova Libraria
Dermoscopy in General Dermatology
Aimilios Lallas, Dimitrios Ioannidese altri
editore: CRC Press
This lavishly illustrated guide from experts will enable practitioners to get the most out of dermoscopy for investigations and treatments in general dermatology.
A Surgical Perspective
editore: Thieme Medical Publishers Inc
The treatment of skin cancer has become an increasingly multispecialty practice. Ongoing surgical and postsurgical advances and emergent factors that predispose patients to these tumors have changed the treatment paradigm. Having a keen understanding of diagnostic, surgical, and nonsurgical treatment options is key to identifying, treating, or referring patients with potential cutaneous malignancies. While Brian R. Gastman's Cutaneous Malignancies: A Surgical Perspective is the first of its kind to emphasize surgical management of skin cancer, several sections are devoted to systemic nonsurgical therapies affecting patient care and surgical intervention. Topics encompassed include prevention, diagnosis, medication management, appropriate margin size, reconstruction methods, and the importance of stellar dermatopathology. Key Highlights The role of Mohs micrographic surgery and radiation in skin cancer treatment Treatment approaches for the two most common forms of skin cancer respectively, basal cell carcinoma and squamous cell carcinoma Surgical treatment of cutaneous malignant melanoma and other high-risk malignancies Clinical insights on completion lymphadenectomy and sentinel node biopsy for melanoma, two topics rarely addressed in context with skin cancer Diagnosis and treatment of rare malignancies including Merkel cell carcinoma, dermatofibrosarcoma protuberans, cutaneous angiosarcoma, and cutaneous leiomyosarcoma More than 400 high-quality illustrations further delineate surgical modalities Edited by an esteemed dual board certified plastic surgeon and otolaryngologist, this definitive book is the most complete guide to surgical management of skin cancer. It is essential reading for plastic surgeons, dermatologists, otolaryngologists, and all clinicians who treat or refer patients with suspected skin cancer.
Jonathan S. Zager, Ragini Kudchadkare altri
editore: Oxford University Press Inc
Melanoma is a concise handbook that identifies best-practice guidelines and presents the most current procedures for the diagnosis and management of melanoma in a succinct and easy-to-read manner. Chapters cover melanoma pathology, biopsy techniques, staging and risk stratification, surgical treatment of localized melanoma, immunotherapy, radiation therapy, and guidelines for resected melanoma, targeted therapy, cytotoxic chemotherapy, and management of brain metastases, mucosal and ocular melanoma, and pediatric melanoma patients. This handbook is a must-have tool for clinicians directly involved in the care of patients with melanoma, including surgical oncologists, medical oncologists, and radiation oncologists.
The Cutaneous Lymphoid Proliferations
A Comprehensive Textbook of Lymphocytic Infiltrates of the Skin
A. Neil Crowson, Cynthia M. Magroe altri
editore: John Wiley & Sons Inc
A masterful and thorough revision of the only single-source, authoritative reference on cutaneous lymphoproliferative disease. * Classic reference for unsurpassed coverage of lymphocytic infiltrates of the human skin * Covers a broad spectrum of topics ranging from the role of the immune system in the pathogenesis of cutaneous lymphocytic infiltrates to one describing the immunohistochemica nd molecular aspects of lymphoid neoplasia. * Each chapter contains an extensive array of clinical vignettes clearly showing the application of principles and treatment techniques discussed in the chapter * Presents a succinct and logical approach to the diagnosis of most cutaneous lymphocytic infiltrates and discusses the interplay between the immune system in the propagation of lymphocytic infiltrates focusing on the role of iatrogenic and endogenous immune dysregulation. The molecular and cytogenetic basis of lymphoid neoplasia is considered in great detail. * Contains hundreds of full-color, high-quality clinical and histologic photographs, with over 200 new images in the new edition
Dermatoscopy of Non-Pigmented Skin Tumors
Pink - Think - Blink
Giuseppe Argenziano, Iris Zalaudeke altri
editore: Apple Academic Press Inc.
Although many skin lesions are pigmented, Dermatoscopy of Non-pigmented Skin Tumors: Pink - Think - Blink addresses non-pigmented lesions, which may be more difficult to diagnose. It discusses dermatoscopy not only as a reliable tool for diagnosis, but also for the monitoring of treatment outcomes following topical therapy. The clinical diagnosis of non-pigmented skin lesions is one of the most challenging in the daily routine. To arrive at a correct diagnosis-or at least an adequate management plan-the clinician needs to collect many pieces of information and put them together like a puzzle. Illustrated with nearly 200 color clinical and dermatoscopic photographs, this book is an invaluable guide for clinicians striving to solve the diagnostic puzzle and correctly identify non-pigmented lesions.
A Case Based Approach
Mai P Hoang, Martin C. Mihm
editore: Springer-Verlag New York Inc.
Melanocytic Lesions: A Case Based Approach provides a concise yet comprehensive guideline on how to diagnose common as well as problematic and challenging melanocytic lesions. In the first 11 chapters, each entity is illustrated by an actual case; followed by discussion of how the diagnosis is reached, of the histologic differential diagnoses and of diagnostic pitfalls and ends with bulleted teaching points. Pertinent and up to date references are included at the end of each chapter. The latter chapters cover current microstaging and classification of melanoma, ancillary techniques including immunohistochemistry as well as available molecular assays and molecular targeted therapy. All figures and glass slides of the discussed cases are hosted online for easy viewing and access. Melanocytic Lesions: A Case Based Approach will serves as a useful resource for pathologists, dermatologists and researchers dealing with melanocytic lesions.
The Illustrated Guide
editore: John Wiley & Sons Inc
Skin lymphomas are relatively rare but potentially fatal. They can easily be misdiagnosed as benign skin diseases. Dermatologists and pathologists need to have a good understanding of the clinical presentations and the pathological correlates of this challenging disease to ensure the correct diagnosis and most appropriate treatment is provided. Skin Lymphoma: The Illustrated Guide is a full-color illustrated text and atlas that combines pathology with clinical features and treatment. Jam-packed with pictures that illustrate key diagnostic points and supplemented by teaching cases to highlight effective decision making. It includes all newly identified entities and provides pointers on how to differentiate these. In addition, it also covers all inflammatory conditions that may simulate skin lymphomas (cutaneous pseudolymphomas). Skin Lymphoma: The Illustrated Guide provides: clinical and pathological guidance on diagnosis of skin lymphomas; clear illustrations to aid visual recognition * Nomenclature according to WHO/EORTC classifications; and, cases to enhance the scope for teaching and learning. This fully refreshed fourth edition continues to provide the clinical excellence that has helped a generation of dermatologists and dermatopathologists to effectively diagnose skin lymphoma.
Dermatologic Principles and Practice in Oncology
Conditions of the Skin, Hair, and Nails in Cancer Patients
Mario E. Lacouture
editore: Wiley-Blackwell (an imprint of John Wiley & Sons Ltd)
This is the first book to focus on frequent and frequently disabling side effects involving the skin, hair, and nails in cancer patients. It provides detailed descriptions of mechanism-of-action in all current oncology drugs and the clinical presentation and mechanisms underlying their dermatologic side effects, alongside carefully presented treatment recommendations, allowing physicians to significantly enhance their care of patients with cancer. Whereas existing oncology and dermatology textbooks only briefly deal with this topic, this resource offers dermatologists and other practitioners a focused perspective on cancer-related skin conditions.
Giovanni Di Lorenzo
L'escissione radicale di una neoformazione cutanea ritenuta atipica, secondo criteri codificati, oppure l'asportazione chirurg
Christine Ko, David J. DiCaudoe altri
editore: Saunders (W.B.) Co Ltd
With a unique combination of targeted online lectures, vast online image collections, and an easy-to-follow supporting atlas, Dr. Elston's highly acclaimed "dermatopathology made easier" approach presents a unique way to master the foundations of this complex dermatology sub-specialty, guiding you through the diagnosis of the most important and common dermatologic pathology findings seen in practice.
Cancer of the Skin
Clay J. Cockerell, Darrell S. Rigele altri
"Cancer of the Skin", edited by Drs. Rigel, Robinson, Ross, Friedman, Cockerell, Lim, Stockfleth, and Kirkwood, is your complete, multimedia guide to early diagnosis and effective medical and surgical treatment of melanoma and other skin cancers. Thoroughly updated with 11 new chapters, this broad-based, comprehensive reference provides you with the latest information on clinical genetics and genomics of skin cancer, targeted therapy for melanoma, the Vitamin D debate concerning the risks and benefits of sun exposure, and other timely topics. A new, multi-disciplinary team of contributors and editors comprised of leading experts in this field offers truly diverse perspectives and worldwide best practices.
Practical Skin Cancer Surgery
From Fundamentals to Advanced
Anthony Dixon, Mileham Hayes
editore: Harcourt Publishers Group (Australia) Pty.Ltd
Biopsy Interpretation of the Skin
Primary Non-lymphoid Neoplasms of the Skin
A. Neil Crowson, Cynthia M. Magroe altri
editore: Lippincott Williams and Wilkins
This new volume of the "Biopsy Interpretation Series" is a practical, superbly illustrated reference on the primary non-lymphoid neoplasms of the skin. The book offers guidelines on how and when to biopsy the skin and then discusses benign melanocytic proliferations, precursor lesions to melanoma, and melanomas. Also included are discussions of basal cell carcinoma, squamous cell carcinoma and its precursors, benign and malignant adnexal neoplasms, and soft tissue neoplasms of the skin and superficial subcutis. A major highlight of the book is the extensive discussion of differential diagnostic considerations and their separation from the main diagnostic entities under consideration. The book features nearly 300 full-color images. A companion Website will provide 400 additional figures, plus a test bank that is ideal for board exam preparation.
Recognition and Management
Robert A. Schwartz
editore: Wiley-Blackwell (an imprint of John Wiley & Sons Ltd)
The second edition of Skin Cancer: Recognition and Management is a definitive clinical reference which comprehensively examines the wide range of premalignant and malignant cutaneous disorders, including melanoma, Kaposi's sarcoma and other sarcomas, cutaneous lymphoma, cutaneous metastatic disease and cutaneous markers of internal malignancy, with emphasis on the most recent advances in diagnosis and management. Fully revised and expanded, this new edition now includes full colour photographs and illustrations throughout to aid recognition and diagnosis, and covers the latest developments and treatment modalities. New chapters include: * Merkel Cell Carcinoma * Dermoscopy Skin Cancer: Recognition and Management is a definitive clinical reference for dermatologists, oncologists, residents and any medical practitioner with an interest in skin cancer.
An Illustrated Guide to Skin Lymphoma
Herr Helmut Kerl, Kevin Gattere altri
editore: Blackwell Publishing Ltd
Skin lymphomas are relatively rare. They may arise in the skin itself and as a by-product of HIV infection, or may arise elsewhere as a result of Hodgkin's disease, B cell lymphomas or leukaemia. Whatever the cause, they can easily be overlooked as psoriasis or dermatitis. Diagnosis of skin lymphoma is difficult and making the wrong diagnosis can prove fatal. Consequently, those in training in dermatology and pathology need to have a good understanding of the clinical presentations and the pathological correlates of this challenging disease. An Illustrated Guide to Skin Lymphoma is a beautiful full-colour illustrated text and atlas that combines pathology with clinical features and treatment. This second edition includes the latest classification systems for cutaneous lymphomas as well as brand new chapters and an expanded section on treatment.