Oncologia dei tessuti molli

Soft Tissue and Bone Tumours is the third volume in the 5th edition ofthe WHO series on the classification of human tumours. This series (also knownas the WHO Blue Books) is regarded as the gold standard for the diagnosis oftumours and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise referencebooks provide indispensable international standards for anyone involved in thecare of patients with cancer or in cancer research, underpinning individualpatient treatment as well as research into all aspects of cancer causation,prevention, therapy, and education.This volume will be of particular interest to pathologists, oncologists,surgeons, and epidemiologists who manage or research soft tissue and bonetumours. Sections are included on all recognized neoplasms of the soft tissueand bone, as well as on genetic tumour syndromes affecting these sites. Sincethe previous edition, there have been changes based on recent molecular andgenetic information, with impact on clinical practice.

Since its first publication more than 35 years ago, Enzinger and Weiss's Soft Tissue Tumors has established itself as the most comprehensive and authoritative reference available on soft tissue pathology. The 7th Edition from Drs. John R. Goldblum, Andrew L. Folpe, and Sharon W. Weiss, continues this tradition with detailed, well-written, logically organized coverage of the full spectrum of these often difficult and challenging tumors. It offers clear guidance to practicing and trainee pathologists on diagnosis of tumors by microscopy, immunohistochemistry, and molecular genetics, as well as a significant amount of clinically significant information of interest to the clinicians who most frequently see these diseases - dermatologists, orthopaedists, and oncologists. Offers practical information on differential diagnosis of tumors of the skeletal muscles, connective tissue, fat, and related structures, helping you accurately diagnose and confidently sign out pathology reports on even the most challenging cases. Provides unsurpassed scope and depth in this complex area with microscopic findings correlated with the latest developments in molecular biology, cytogenetics, and immunohistochemistry, for a comprehensive and integrated approach to evaluation and diagnosis. Incorporates new knowledge on recently identified entities, next-generation sequencing (NGS), molecular diagnostic techniques, and immunohistochemical and genetic features of soft tissue tumors, providing up-to-date diagnostic and prognostic information that will inform day-to-day therapeutic decisions. Features nearly 2,000 high-quality images that clearly capture the clinical, macroscopic and microscopic features of benign and malignant conditions, helping you relate these characteristics to their specific classifications. Utilizes a logical, well-structured format including summary outlines at the beginning of each chapter, a color-coded page design, and a consistent approach to every entity, enabling you to navigate the text quickly, improve turnaround time when diagnosing a specimen, and clearly report on the prognosis and therapeutic management options. Includes abundant algorithms, tables, and graphs to facilitate rapid decision making. Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices

Covering all aspects of soft tissue pathology, this highly regarded volume in the Diagnostic Pathology series is an excellent point-of-care resource for pathologists at all levels of experience and training-both as a quick reference and as an efficient review to improve knowledge and skills. Specifically designed as a point-of-care resource, the updated third edition uses a templated, highly formatted design; concise, bulleted text; and superior color images throughout that demonstrate the variety of differentiating factors in soft tissue tumors. Includes new chapters on recently described entities such as superficial CD34-positive fibroblastic tumor and atypical spindle cell lipomatous tumor, with numerous images detailing characteristic histology for ease of recognition Covers recent advances and discoveries in immunohistochemistry and molecular pathology of soft tissue tumors, including new IHC antibodies FOSB and H3k27me3, ALK-1 expression in angiomatoid fibrous histiocytoma, and entries on BCOR-CCNB2 fusion-defined sarcoma, novel PDGFD rearrangements in dermatofibrosarcoma protuberans, and RB gene loss in acral fibromyxoma Includes extensive new 8th edition AJCC staging information for soft tissue sarcomas in convenient table format Features more than 2,000 annotated images throughout, including gross pathology, a wide range of stains, and detailed medical illustrations, with coverage of key diagnostic features for each tumor as well as morphologic variants Features easy-to-reference chapters that begin with Key Facts, followed by terminology, clinical issues, macro- and microscopic features, ancillary tests and a list of differential diagnoses with bulleted characteristics Provides an organized framework that includes "Approach to Diagnosis" chapters designed to help you successfully recognize and diagnose challenging soft tissue tumors with the availability of common patterns and histologic features Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices

Don't skim the surface of diagnosis; gain in-depth, full-color insight with Cutaneous Soft Tissue Tumors. This succinct, yet meaningful, field guide deconstructs all presentations in one easy-to-read and comprehensive text. With over 2,000 color images right at your fingertips, you'll examine magnified, panoramic, and architectural views of each proliferation, fostering maximum understanding. Add Cutaneous Soft Tissue Tumors to your bookshelf and you'll master the essential skill of histopathological diagnosis to deliver the best courses of treatment for your patients. Key features: including over 2,000 full color images in field atlas format; it includes conventional hematoxylin and eosin stained samples at four different magnifications and panoramic views; it covers all cutaneous soft tissue tumors - common and rare; coverage includes most recent molecular advances of each neoplasm and extensive histopathological micrographs throughout. Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access to: complete content with enhanced navigation; a powerful search tool that pulls results from content in the book, your notes, and even the web; cross-linked pages, references, and more for easy navigation; highlighting tool for easier reference of key content throughout the text; ability to take and share notes with friends and colleagues and quick-reference tabbing to save your favorite content for future use.

On account of its unrivalled imaging capabilities and sensitivity, magnetic resonance imaging (MRI) is considered the modality of choice for the investigation of physiologic and pathologic processes affecting the bone marrow. This book describes the MRI appearances of both the normal bone marrow, including variants, and the full range of bone marrow disorders. Detailed discussion is devoted to malignancies, including multiple myeloma, lymphoma, chronic myeloproliferative disorders, leukemia, and bone metastases. Among the other conditions covered are benign and malignant compression fractures, osteonecrosis, hemolytic anemia, Gaucher's disease, bone marrow edema syndrome, trauma, and infective and non-infective inflammatory disease. Further chapters address the role of MRI in assessing treatment response, the use of contrast media, and advanced MRI techniques. Magnetic Resonance Imaging of the Bone Marrow represents an ideal reference for both novice and experienced practitioners.

Soft tissue sarcoma is an uncommon disease with a historically ominous prognosis, but there has been a great deal of progress in the last two decades in the understanding of these diseases, and accurate prognostic and therapeutic information is now available that removes much of the mystique.