Behavioural Neurology of Anti-epileptic Drugs
A Practical Guide
Andrea E. Cavanna
editore: Oxford University Press
The Prescriber's Guide
Hsiangkuo Yuan, Michael J. Marmurae altri
editore: Cambridge University Press
Essential Neuropharmacology: The Prescriber's Guide reviews the full range of medications used by neurologists in clinical practice. Expert knowledge is given about the best use of medications in patient care. Each drug listing contains the full range of indications, their advantages and disadvantages, and tips for dosing and avoiding adverse effects. Evidence is taken from recent clinical trials, which helps the reader relate the drug descriptions to everyday clinical practice. Where appropriate, off-label uses are also described. The detailed descriptions of each medication enable the user to make quick and informed decisions with the confidence they need to serve the clinical needs of their patients effectively. The new edition is fully updated throughout. Major new additions include neuro-oncology drugs, new multiple sclerosis agents, sleep medications and new formulations. This book is an essential, user-friendly reference suitable for neurologists at all stages of their careers.
Un veleno che cura. Storia, usi e abusi della tossina botulinica
Mauro Porta, Vittorio A. Sironi
"La tossina botulinica ha influenzato la terapia neurologica come nessun altra sostanza" ha affermato recentemente Wolfang Jost, famoso neurologo tedesco. In effetti da quando è iniziato l'impiego in campo clinico - non più di qualche decennio fa - le sue applicazioni sono andate ampliandosi, non sempre in maniera controllata, sicché spesso l'uso si è trasformato in abuso. Soprattutto nel campo labile e controverso, tra cura e consumo, della medicina estetica e ancor maggiormente della "medicina cosmetica". Quest'ultima più che al benessere sanitario del malato mira a ottenere il "bellessere" estetico del consumatore. La storia della scoperta del botulismo e del germe che produce la neurotossina responsabile di questo letale evento, l'evoluzione delle tappe che hanno portato a comprenderne l'utilità terapeutica, un'esauriente rassegna scientifica degli impieghi attuali e futuri, un'articolata riflessione antropologica, sociale ed etica degli usi e degli eccessi di questa "moda curativa" emergono chiaramente dai contributi multidisciplinari presenti nel libro, indirizzato, oltre che agli specialisti, anche a tutte le persone che desiderano conoscere e approfondire i problemi aperti e controversi dell'ambito sanitario odierno.
PRONTUARIO DEI FARMACI PER IL SISTEMA NERVOSO CENTRALE 2012/2013
a cura di R. Torta
editore: Edi. Ermes
A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities
Jose de Leon
editore: Springer-Verlag New York Inc.
Emotional, behavioral, and neuropsychiatric conditions are common in individuals with intellectual disabilities (IDs), most notably epilepsy, aggression, self-injurious behaviors, and bipolar and other mood disorders. Despite the prevalence of such problems, there is a scarcity in the literature of reliable information on medical treatments for those with IDs. A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities provides a detailed framework for prescribing for this challenging population. Featuring the most up-to-date information on factors that inform prescribing, the Guide addresses basic issues and controversies (e.g., the rift between evidence-based and personalized medicine) in treating adults with cognitive deficits. Clients' specific needs are emphasized in developing appropriate and effective pharmacological intervention for improved outcomes and quality of life. Drugs discussed in the Guide include carbamazepine, clonazepam, diazepam, ethosuximide, felbamate, gabapentin, lacosamide, lamotrigine, levetiracetam, lithium, lorazepam, oxcarbazepine, phenobarbital, phenytoin, pregabalin, primidone, rufinamide, tiagabine, topiramate, valproate, and zonisamide. For each of these compounds, the guidelines cover: * Indications for use; relative and absolute contraindications.* Assessment during treatment; therapeutic drug monitoring; warning signs and symptoms for caretakers.* Dosage: administration; initial and maximum recommended dosage; modifications associated with drug-drug interactions, personal characteristics, and (where appropriate) genetic variations.* Adverse drug reactions: common, relatively uncommon, and potentially lethal, plus risk of metabolic syndrome.* Guidelines for discontinuation.* References, tables, and drug utilization reviews. A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities is an indispensable decision-making reference for psychiatrists, neuropsychologists, psychopharmacologists, neurologists, internists, and clinical psychologists.
Principles of Drug Therapy in Neurology
Michael V. Johnston, Robert Gross
editore: Oxford University Press Inc
Since the first edition of this book was published in 1992, the number of pharmacological therapies available for treating neurological disorders has grown exponentially. This new edition brings the book fully up-to-date, and features PET scans to illustrate brain action, and new chapters on practical therapeutics and clinical trials.
Drug Discovery for Nervous System Diseases
Franz F. Hefti
editore: John Wiley & Sons Inc
The book focuses on drug discovery for psychiatric and neurological diseases, which is in a phase of explosive growth. Chapters are divided into two major sections. The first section presents fundamentals of drug discovery, highlighting the modern techniques and approaches of drug discovery in biotech and pharmaceutical companies. Specific aspects of brain diseases, such penetration of the blood-brain barrier, are addressed. The author pays particular attention to clinical proof-of-concept research. Discussion of drug discovery for the major nervous system diseases represents the second section of the book. Each chapter looks at a particular class of disease, beginning with a summary of current understanding of disease mechanism and treatment, followed by thorough discussion of novel targets and emerging drugs.
Brian S. Meldrum, Emilio Peruccae altri
editore: Lippincott Williams and Wilkins
The thoroughly revised, updated Fifth Edition of this classic is the most comprehensive, current, and authoritative reference on all anticonvulsants available today. This edition features detailed profiles of newer drugs - including levetiracetam, oxcarbazepine, tiagabine, topiramate, and zonisamide - and new chapters on use of antiepileptic drugs in children and during pregnancy. Drugs are covered in alphabetical order and in an easy-to-follow format: mechanisms of action; chemistry, biotransformation, and pharmacokinetics; interactions; clinical efficacy and use; and, adverse effects. Coverage of clinical use includes nonepileptic and psychiatric disorders where appropriate. This edition has been trimmed to manageable size by shortening chapters on older, less frequently used drugs.
Neuropsychopharmacology: The Fifth Generation of Progress
An Official Publication of the American College of Neuropsychopharmacology
Charles B. Nemeroff, Dennis Charneye altri
editore: Lippincott Williams and Wilkins
Receive FREE On-Line Access through the American College of Neuropsychopharmacology website when you purchase the book! Simply return the card enclosed in the product shrink wrap. A password will be sent to you via e-mail. For a sample chapter, and to learn more about the ACNP, click here. Thoroughly updated and completely reorganized for a sharper clinical focus, the Fifth Edition of this world-renowned classic synthesizes the latest advances in basic neurobiology, biological psychiatry, and clinical neuropsychopharmacology. The book establishes a critical bridge connecting new discoveries in molecular and cellular biology, genetics, and neuroimaging with the etiology, diagnosis, and treatment of the full spectrum of neuropsychiatric disorders. Nine sections focus on specific groups of disorders - disorders of development; schizophrenia and related disorders; anxiety and stress disorders; affective disorders; Alzheimer's and other dementias; substance use disorders; impulsive and compulsive disorders; movement disorders and paroxysmal disorders; and chronobiology and sleep disorders. Each group of disorders is discussed in detail, including clinical course, genetics, neurobiology, neuroimaging, and current and emerging therapeutics. Four sections cover neurotransmitter and signal transduction, emerging methods in molecular biology and genetics, emerging imaging technologies and their psychiatric applications, and drug discovery and evaluation. Compatibility: BlackBerry[registered] OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile[trademark] Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC.
Neurological Aspects of Substance Abuse
John C. M. Brust
editore: Butterworth-Heinemann Ltd
As more drugs are "designed," more research is being done, and substance abuse remains a serious international problem, this reference remains important to neurologic literature.
The Biochemical Basis of Neuropharmacology
Floyd E. Bloom, Jack R. Coopere altri
editore: Oxford University Press Inc
Aside from the usual updating of material, the major change in this edition is an extensive re-writing of the chapter on memory and learning to emphasize that genes that are involved in behaviour are not immutable but their expression can be modified by transcription factors. Thus, with respect to learning, that old question about which is more important, nature or nuture, genetics or environment, should be answered with the question, which leg is more important for walking, the left or the right?