Oncologia apparato gastroenterico
Tumors of the Esophagus and Stomach
Elizabeth A. Montgomery, Robert D. Odzee altri
editore: American Registry of Pathology
pagine: 416
Since the publication of the previous edition of Tumors of the Esophagus and Stomach, great advances in many areas of tumor biology have led to a better understanding of the pathogenesis, pathology, and molecular biology of epithelial and stromal malignancies of the upper gastrointestinal tract. Many of these advances have led to specific improvements in diagnosis, prognosis, treatment, and thus, survival in patients affected by these tumors. This edition of the Fascicle was written to highlight these advances, and more specifically, to help pathologists diagnose diseases more accurately and understand how pathology contributes to clinical treatment in the new age of personalized and targeted therapy.
Notable advances described in this publication include:
1) expansion of our understanding of the pathologic features and molecular pathogenesis of carcinomas of the esophagus and stomach, most of which develop through a chronic inflammation-metaplasia-dysplasia-carcinoma sequence. Important refinements in the classification of neoplastic precursor lesions have been made since the last AFIP series, including the morphologic and endoscopic subtypes, and this has led to improvements in surgical treatment with a strong trend toward minimization in the form of endoscopic mucosal and submucosal dissections
2) discovery of new diseases, such as gastric adenocarcinoma and proximal polyposis syndrome (GAPPS), a special variant of familial adenomatous polyposis, and significant advances in our knowledge regarding the molecular characterization of genetic polyposis syndromes
3) great expansion in the molecular-pathology correlation, morphologic diversity, classification, and therapeutic options of gastrointestinal stromal tumors (GISTs)
4) reclassification and refinement of prognostic factors related to neuroendocrine tumors
5) improvements in the role of cytology in the diagnosis of tumors of the upper gastrointestinal tract.
This book has been written with the pathologist in mind first by using tables that illustrate salient pathologic, molecular, and differential diagnostic features of key entities that are often difficult to distinguish from each other. Specific color photographs of classic tumors and morphologic variants often difficult to recognize are used throughout.
Atlas of Gastrointestinal Pathology: A Pattern Based Approach to Neoplastic Biopsies
Elizabeth A. Montgomery, Christina Arnolde altri
editore: Lippincott Williams and Wilkins
pagine: 656
Selected as a Doody's Core Title for 2022 and 2023!
Closely mirroring the daily sign-out process, Atlas of Gastrointestinal Pathology: A Pattern Based Approach to Neoplastic Biopsies is a highly illustrated, efficient guide to accurate diagnosis. This practical reference uses a proven, pattern-based approach to clearly explain how to interpret challenging cases by highlighting red flags in the clinical chart and locating hidden clues in the slides. Useful as a daily “scope-side guide,†it features numerous clinical and educational features that help you find pertinent information, reach a correct diagnosis, and assemble a thorough and streamlined pathology report.
More than 1,600 high-quality photomicrographs capture the subtle morphologic spectrum of neoplastic processes of the tubular GI tract. Each image is captioned with key diagnostic considerations and includes call-outs showing subtle features and diagnostic clues.
Practical tools throughout the text include:
Tables that emphasize salient clinicopathologic features, management implications, and therapeutic options o Discussions of how and when to incorporate molecular tools o Checklists for key elements of the diagnostic approach and sample notes for inclusion in pathology reports
Relevant endoscopic images, photographs of select gross specimens, and medical figures
Brief reviews of normal histology that provide contrast to succeeding patterns
“Pearls and Pitfalls†and “Near Misses†sections with lessons from real life sign-out experience
“Frequently Asked Questions†sections that discuss common diagnostic dilemmas
“Sample Note†sections that offer a template of how to synthesize complicated or especially challenging topics
Quizzes in every chapter that provide experience with high-yield, board-style teaching topics
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Colon and Other Gastrointestinal Cancers
Cancer: Principles & Practice of Oncology
Steven A. Rosenberg, Theodore S. Lawrence
editore: Lippincott Williams and Wilkins
pagine: 792
Selected from the world's leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Colon and Other Gastrointestinal Cancers: Cancer: Principles & Practice of Oncology, 10th Edition, offers a comprehensive and balanced view of this rapidly changing field, meeting the needs of oncology practitioners, fellows, and others who need an in-depth understanding of colon and GI cancer. The print reference gives you the solid, dependable guidance you've come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors. Key Features:* Delivers focused, comprehensive information on colon and GI cancer drawn from the world's leading cancer textbook, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology.* Covers the molecular biology of the esophagus, stomach, liver, pancreas and colorectal cancer; genetic testing of the stomach, colon, and pancreas; and cancers of the colon and entire GI tract.*
Discusses in detail the growing importance of prevention and screening, giving you the understanding you need to improve your patients' chances for a healthier, cancer-free life.* Explains how the latest developments in biologic therapy applies to cancers of the colon and GI tract.* Provides exhaustive coverage of combined modality cancer treatment, helping you determine when and how to integrate modalities in patient treatment.* Ensures that you're fully up to date thanks to easy, mobile access to quarterly updates.Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like:*Complete content with enhanced navigation*Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web*Cross-linked pages, references, and more for easy navigation*Highlighting tool for easier reference of key content throughout the text* Ability to take and share notes with friends and colleagues*Quick reference tabbing to save your favorite content for future use
Esophageal Cancer and Barrett's Esophagus
David Ilson, Eric Van Cutseme altri
editore: John Wiley & Sons Inc
pagine: 304
Esophageal Cancer and Barrett s Esophagus, 3E, focuses on these two common and key conditions that affect the esophagus, providing expert guidance to their pathogenesis, cause, prevention, diagnosis and clinical management. Top international names in the field examine each of the many issues involved, using the very latest evidence-based research, and clear, didactic advice allows the reader to understand the best methods of diagnosis and clinical management of each condition whether early or late stage. Well-illustrated and fully revised to include the latest in ACG/ASG/UEGW guidelines, it is the perfect consultation tool for gastroenterologists and oncologists managing patients with cancer of the esophagus. It is also ideal for teaching residents and fellows optimum patient management, and for identifying areas requiring future research.
TUMORS OF THE GALLBLADDER, EXTRAHEPATIC BILE DUCTS, AND VATERIAN SYSTEM
AFIP ATLAS OF TUMOR PATHOLOGY SERIES 4
editore: AFIP - ARP
pagine: 613
Gastric Cancer
Principles and Practice
Vivian E. Strong
editore: Springer International Publishing AG
pagine: 333
This volume provides the most comprehensive and complete resource available on all aspects of gastric cancer and it's management. The book covers topics such as oncologic approaches to staging, treating, and following patients, filling a critical need for resource materials on these areas. As multidisciplinary care is an integral part of gastric cancer treatment, this text is unique in including a renowned group of expert authors from a variety of disciplines, including pathology, gastroenterology, medical oncology, surgery and clinical genetics. In addition, authors from an international pool of gastric cancer experts have covered the breadth of practice and understanding globally. Edited and organized by an expert from one of the most highly respected cancer institutions in the country, Gastric Cancer: Principles and Practice is an expert review of this field, serving as a valuable reference for physicians in training and in practice, as well as for researchers who are interested in the scope of issues and advances in this important malignancy.
Total, Subtotal and Proximal Gastrectomy in Cancer
A Color Atlas
Walter Siquini
editore: Springer Verlag
pagine: 216
This richly illustrated volume describes the performance of total and subtotal gastrectomy with extended D2 lymphadenectomy by providing a detailed step-by-step guide to both manual and mechanical procedures. Gastric cancer is the fourth most commonly occurring cancer and the second most common cancer-related cause of death worldwide, and surgery remains the only potentially curative treatment. Although several aspects of surgical management are still controversial, all guidelines for the treatment of curable gastric cancer recommend subtotal gastrectomy (for tumors located in the antrum and corpus) or total gastrectomy (for tumors located in the fundus) with extended D2 lymphadenectomy. Various technical tips and secrets are revealed that serve to simplify the procedure and simultaneously make it more effective: by rendering esophagojejunal and gastrojejunal anastomosis more secure, the risk of leakage is minimized. High-quality intraoperative color photographs and drawings covering all steps facilitate understanding of these complex operations and will prove an invaluable tool for surgeons, residents and professionals in the field.
Laparoscopic Gastrectomy for Gastric Cancer
Surgical Technique and Lymphadenectomy
Chang-ming Huang, Chao-Hui Zheng
editore: Springer
pagine: 344
This book presents surgical techniques and detailed illustrations of laparoscopic gastrectomy for gastric cancer, focusing on effective, concise steps and techniques. It describes in detail the perigastric anatomy, and the incidences of each anatomical structure are analyzed statistically. It also discusses lessons learned and best practices in the management of gastric cancer patients, and includes video captures of precise operational techniques -essential resources for gastrointestinal laparoscopic surgeons. Given its close connection to clinical practice, it offers a valuable reference work for general surgeons and residents.
Multidisciplinary Treatment of Colorectal Cancer
Staging - Treatment - Pathology - Palliation
Gunnar Baatrup
editore: Springer International Publishing AG
pagine: 289
This book is intended as the equivalent of the Swiss Army knife for all members of colorectal cancer (CRC) multidisciplinary teams and those training in the fields of CRC management. It describes how to organize the team and explains the basic principles within the different disciplines involved in the treatment and care of CRC patients. Important, up-to-date knowledge is provided on visualization techniques, surgery, oncological treatment, palliation, and pathology, with special focus on controversies and aspects of interest to all team members. Care has been taken to ensure that each specialty-specific chapter will be approachable for team members from other specialties or professions, thereby facilitating an effective interdisciplinary approach to teamwork. The authors include leading European doctors and scientists who have influenced the development of the multidisciplinary team concept as well as other aspects of high-quality, individualized treatment of CRC patients.
Biopsy Interpretation of the Gastrointestinal Tract Mucosa
Volume 2: Neoplastic
Elizabeth A. Montgomery, Lysandra Voltaggio
editore: Lippincott Williams and Wilkins
pagine: 352
Gastrointestinal mucosal biopsies are an active part of the pathologist's day and have increased in the past few years as endoscopic screening has become more commonplace. This new full-color Second Edition of "Biopsy Interpretation of the Gastrointestinal Tract Mucosa" has been expanded into two concise, comprehensive volumes to offer more complete coverage of both non-neoplastic and neoplastic entities. Like the other books in the "Biopsy Interpretation Series", these volumes are practical references for pathologists to use when making diagnostic decisions based on biopsy specimens. Volume 2 of this Second Edition focuses on interpretation of neoplastic gastrointestinal mucosal biopsies. Coverage is geared to daily practice and includes mucosal biopsies from the esophagus, stomach, small intestine, large intestine, and anus. A companion website will include all of the 300 print illustrations plus an additional 750 e-figures. Volume 1 focuses on non-neoplastic biopsies and published in November 2011.
Tumore del colon nell'era delle terapie personalizzate
Massimiliano Berretta
editore: Verduci Editore srl
pagine: 190
Volume grande formato (22 x 30) di 190 pagine, numerose illustrazioni a colori, e rilegato con copertina rigida stampata a colori e plastificata.
La presente monografia si prefigge come obiettivo prioritario di mettere a disposizione del lettore, le più recenti conoscenze nel vasto campo pluridisciplinare del carcinoma colorettale, in particolare quelle relative all’epidemiologia, alla genetica, alla chemioprevezione, all’anatomia patologica, alla chirurgia, alla radioterapia, alla chemioterapia, alle terapie biologiche ed alle interazioni varie che si determinano velocemente e che sono in continuo sviluppo. Per l’ampiezza delle problematiche affrontate, la monografia è indirizzata allo studente in medicina che voglia approfondire questo specifico argomento, allo specialista oncologo, al chirurgo, al radioterapista, ma anche all’internista, all’epidemiologo ed al medico di base, cultore dell’argomento. In pochi altri tumori come quelli del colon-retto si sono sviluppate in così poco tempo nuove conoscenze biologiche da una parte e nuove strategie terapeutiche innovative dall’altra. Tutto ciò ha determinato un significativo miglioramento per quanto riguarda la prevenzione, la diagnostica da una parte e le strategie terapeutiche dall’altra (sia nelle fasi iniziali che avanzate della malattia). Infatti, negli ultimi 20-30 anni abbiamo assistito ad una rivoluzione nelle conoscenze sui tumori del grosso intestino, nel campo genetico-molecolare, nella ricerca traslazionale, nella diagnostica per immagini, nell’approccio multimodale e nelle terapie chirurgiche, tant’è, fino agli anni ’80 del secolo scorso una monografia sul carcinoma colorettale avrebbe affrontato quasi esclusivamente le problematiche della chirurgia, ad opera delle innovazioni introdotte da grandi maestri quali Lembert, Miles, Hartman, Goligher, Corman, Valdoni, Knight e Griffen, Heald e Ryall. Oggi il ruolo del chirurgo, benché sempre di primaria importanza, è ricollocato in un ambito multidisciplinare e le decisioni successive all’atto operatorio sono subordinate ad un “team” di esperti, in primo piano l’oncologo, che da angolature diverse valutano il tumore. Questo volume ha anche il pregio di voler sottolineare quanto è complessa ma essenziale l’interazione tra terapie chirurgiche e mediche nell’approccio a questi tumori, anche quando siano in fase metastatica, il che era senza dubbio più difficile da affrontare appena qualche anno fa. Ad esempio, oggi si può arrivare, grazie al supporto della terapia biologica, a rendere operabili pazienti che fino alla fine del secolo scorso sarebbero stati giudicati inoperabili in senso oncologicamente radicale. Sono altresì cadute le barriere discriminanti legate al fattore eta` ed a patologie quali l’infezione da HIV, sicché in queste categorie di pazienti la concomitanza di un carcinoma del colon-retto non è più una controindicazione a trattamenti con finalità curative. Inoltre, va ricordato come altri fattori, quali l’alimentazione e l’attività fisica, giochino un ruolo importante nello scenario di questa importante patologia e su tali fattori bisognerebbe intervenire mediante massicce campagne d’informazione volte ad “educare” la popolazione generale.Non bisogna dimenticare i fattori genetici che frequentemente vengono sottovalutati, tenendo conto che spesso i pazienti che si avvicinano per la prima volta all’oncologo, con una diagnosi di cancro del colon-retto, hanno familiari con lo stesso tipo di tumore e mai indirizzati ad uno screening appropriato. Mentre nel tumore della mammella e nel tumore del collo dell’utero le campagne di prevenzione hanno sensibilizzato la maggioranza della popolazione, per quanto riguarda il cancro del colon-retto in Italia siamo a percentuali inferiori al 10% della popolazione che si sottopone a screening. Fortunatamente abbiamo assistito negli ultimi anni a parecchie iniziative regionali per promuovere lo screening del carcinoma colorettale, ma occorre ancora da fare molto, ed anche in tal senso la nostra monografia vuole offrire un contributo culturale.
ABC of Colorectal Cancer
Annie Young, David Kerre altri
editore: Wiley-Blackwell (an imprint of John Wiley & Sons Ltd)
pagine: 88
Colorectal cancer is a common cause of morbidity and mortality in which prevention, screening and early detection are vital. Beginning with the patient perspective and following the patient pathway, this new second edition covers epidemiology and prevention, screening programmes, decision support networks, the role of primary care, and supportive care for patients with colorectal cancer. The ABC of Colorectal Cancer provides the core knowledge on clinical genetics, diagnosis, imaging, therapy and surgery options and the latest evidence based guidelines for treating and managing colorectal cancer patients within the multidisciplinary team. Highly illustrated and accessible, it covers the full spectrum of the disease to provide the basis to make a real difference to clinical management. This is an invaluable practical guide for the non-specialist on all aspects of colorectal cancer, and is ideal for general practitioners, junior doctors, nurses and allied health professionals.
Advances in Surgical Pathology
Gastric Cancer
Dongfeng Tan, Gregory Lauwers
editore: Lippincott Williams and Wilkins
pagine: 348
Advances in Surgical Pathology: Gastric Cancer provides a concise, updated review of the pathological characteristics of gastric cancer, with an emphasis on exploring practical issues and recent developments. The book features current and emerging concepts in the field of gastric cancer, a disease whose management requires a multidisciplinary approach in which pathology plays a key role. Its six sections cover the essential histopathology of gastric cancer as well as related topics such as imaging evaluation, molecular diagnosis, and personalized treatment, among other areas of interest. Individual chapters written by international experts in the fields of pathology, gastrointestinal medical oncology, cancer epidemiology, and gastrointestinal radiology, address the fundamental issues surrounding gastric cancer, including its epidemiology, basic diagnostic features, differential diagnoses, pitfalls and complications, and treatments. Endoscopic evaluation and histology correlation are emphasized. The screening, clinical management, and treatment of gastric cancer are summarized in related book sections.
Recent findings regarding the roles of immunohistochemistry and molecular testing in the diagnosis, prognosis, and personalized treatment of gastric cancer are also reviewed. The book also includes current knowledge regarding the molecular alteration of gastric cancer carcinogenesis and its impact on patient care.
Gastrointestinal Oncology
Charles D. Blanke, Claus Rodele altri
editore: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
pagine: 460
"Gastrointestinal Oncology" is an evidence-based, practical reference intended to assist in the diagnosis and management of patients with gastrointestinal malignancies. It is designed to be as user friendly as possible and is distinguished by the extremely practical, concrete nature of the information presented and by the multidisciplinary approach adopted. In addition to disease-oriented chapters spanning sites from the esophagus to the anus, non-anatomic subjects such as modern imaging techniques are also addressed. Translational science is supplied where useful in the decision-making process. All of the authors are internationally recognized experts. This book is an ideal resource for oncologists, surgeons, gastroenterologists, and primary-care providers looking for the latest and best information on how to deal with a wide variety of gastrointestinal neoplasms.
Specialty Imaging: Gastrointestinal Oncology
Akram M. Shaaban, Alex Schabele altri
editore: Amirsys, Inc
pagine: 392
Amirsys is pleased to announce the publication of "Specialty Imaging: Gastrointestinal Oncology", our only book focused entirely on gastrointestinal cancers. Dr. Akram Shabaan and team have skillfully assembled over 1,000 high-quality images that show the various tumor stages for cancers of the small intestine, esophagus, appendix, colon, stomach, gall bladder, pancreas, and more. These images and over 320 pages of easy-to-read bulleted text masterfully guide the clinician and researcher through a sophisticated discussion of a variety of imaging appearances, stages, and treatment options. The book includes the hot-off-the-press Seventh Edition AJCC cancer staging tables, which provide the definitions for TNM and AJCC prognostic groups for all gastrointestinal cancers. This handy reference is perfect for radiologists, oncologists, and other medical professionals who demand accuracy.
Gastric Cancer
Richard M. Gore
editore: Cambridge University Press
pagine: 228
Gastric adenocarcinoma is the second most common cancer worldwide. It is usually diagnosed at a late stage and prognosis is poor; even with modern diagnostic and treatment methods the 5-year survival is only 10%. Improvements in overall patient survival can only be achieved by earlier diagnosis and by tailored therapeutic strategies based on tumor type, location and stage at presentation. This volume provides a state-of-the-art, integrated diagnostic and therapeutic approach to patient management. The role of the upper GI series, endoscopy, endoscopic ultrasound, MDCT, MRI, and PET/CT in the diagnosis, staging and follow-up of patients with gastric cancer is emphasized. The relative strengths and limitations of these diagnostic examinations will be presented in context with the most recent epidemiologic, pathologic, and therapeutic concepts regarding this tumor. With expert contributions from members of an international multidisciplinary team, this is an invaluable guide to the diagnosis and management of gastric malignancies.
Colorectal Surgery
A Companion to Specialist Surgical Practice
Robin K. S. Phillips
editore: Saunders (W.B.) Co Ltd
pagine: 346
Ever since the publication of the first edition in 1997, the "Companion to Specialist Surgical Practice" series has met the needs of surgeons in higher training and practising consultants by providing contemporary, evidence-based information on the sub-specialist areas relevant to their general surgical practice. All eight volumes are thoroughly edited and supported by evidence-based references to support key recommendations. This new Fourth Edition brings together the relevant state-of-the-art specialist information that the editors and authors consider important for the practising sub-specialist general surgeon. Purchase of a print book also includes a downloadable version of the eBook.
Methods of Cancer Diagnosis, Therapy and Prognosis
Colorectal Cancer
M. A. Hayat
editore: Springer-Verlag New York Inc.
pagine: 541
This volume discusses various methodolo- discoveries and their translation to clinical gies for the diagnosis, therapy, and prog- practice. Oncology will benefit the most nosis of colorectal cancer (CRC). Volumes from these various advanced methodologies, 1, 2, 3, and 4 of this series present similar as a combination of the rapies and person- methods for breast cancer, lung and pros- ized medicine will improve early detection tate cancers, and gastrointestinal cancer, of CRC and other cancer types. respectively. The current volume presents The use of anticancer agents, including surgical, radiological, and molecular thera- 5-fluorouracil, fluoropyrimidines, leuc- pies and prognostic biomarkers for CRC. orin, irinotecan, oxaliplatin, raltitrexed, A large number of methods, including capecitabine, cetuximab, and bevacizumab, immunohistochemistry, in situ hybridiza- is also presented. Preoperative chemora- tion, immunoscintigraphy, RT-PCR, free otherapy is compared with postoperative circulating DNA levels in blood and stool, chemoradiotherapy.
In addition, treatments ultrasonography, CT, PET, and MRI are such as immunotherapy, laparoscopic detailed for diagnosing CRC at various surgery, radiofrequency ablation, pho- stages of development. Imaging technolo- dynamic therapy, and preoperative che- gies for assessing the treatment results are radiotherapy, are presented. Preoperative also included as are details related to colon- short-course radiation for resectable r- oscopy and sigmoidoscopy. In addition, the tal cancer is also detailed. role of mircoRNA as a biomarker for this This volume included the efforts of 89 type of cancer is elaborated.