Medicina nucleare

Il presente volume rappresenta un aggiornamento ed estensione dei precedenti volumi, espressione di un'iniziativa promossa dal

Prostate cancer imaging has evolved rapidly dur¬ing the last years, moving toward a more person¬alized approach. The comprehensive evaluation of tumor biology alongside the evaluation of different patterns of expression by cancer clones has become an attractive field of investigation for molecular imaging. Next-generation imaging represents a ground-breaking approach, deliver¬ing to patients more accurate diagnostic proce¬dures and leading clinicians to identify specific targets for radioligand therapy. The theragnos¬tic approach-therapy and diagnosis using the same probe-represents, probably, one of the most important innovations in the management of prostate cancer. Hence, the rapid introduction into clinical practice of small molecules bind¬ing prostate-specific membrane antigen (PSMA) represents a brilliant example of how transla¬tional imaging should work. Prostate cancer, as one of the most frequent tumors and causes of death, still represents a hard enemy to fight, but next-generation imaging and radioligand therapy are innovative weapons that might contribute to improve outcomes and quality of life in men affected by the disease

Covering both the fundamentals and recent developments in this fast-changing field, Essentials of Nuclear Medicine and Molecular Imaging, 7th Edition, is a must-have resource for radiology residents, nuclear medicine residents and fellows, nuclear medicine specialists, and nuclear medicine technicians. Known for its clear and easily understood writing style, superb illustrations, and self-assessment features, this updated classic is an ideal reference for all diagnostic imaging and therapeutic patient care related to nuclear medicine, as well as an excellent review tool for certification or MOC preparation. Provides comprehensive, clear explanations of everything from principles of human physiology, pathology, physics, radioactivity, radiopharmaceuticals, radiation safety, and legal requirements to hot topics such as new brain and neuroendocrine tumor agents and hybrid imaging, including PET/MR and PET/CT. Covers the imaging of every body system, as well as inflammation, infection and tumor imaging; pearls and pitfalls for every chapter; and pediatric doses and guidelines in compliance with the Image Gently and Image Wisely programs. Features a separate self-assessment section on differential diagnoses, imaging procedures and artifacts, and safety issues with unknown cases, questions, answers, and explanations. Includes new images and illustrations, for a total of 430 high-quality, multi-modality examples throughout the text. Reflects recent advances in the field, including updated nuclear medicine imaging and therapy guidelines . Updated dosimetry values and effective doses for all radiopharmaceuticals with new values from the 2015 International Commission on Radiological Protection . Updated information regarding advances in brain imaging, including amyloid, dopamine transporter and dementia imaging . Inclusion of Ga-68 DOTA PET/CT for neuroendocrine tumors . Expanded information on correlative and hybrid imaging with SPECT/CT . New myocardial agents . and more. Contains extensive appendices including updated comprehensive imaging protocols for routine and hybrid imaging, pregnancy and breastfeeding guidelines, pediatric dosages, non-radioactive pharmaceuticals used in interventional and cardiac stress imaging, and radioactivity conversion tables. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Master the content you need to know for the Core Exam module for nuclear medicine! This unique, image-rich resource is an excellent tool for self-assessment and exam prep, whether you're studying for the Core Exam or Maintenance of Certification. More than 300 questions, answers, and explanations accompany hundreds of high-quality images, in a format that mimics the Core Exam. Nuclear Medicine: A Core Review tests your knowledge of every aspect of the exam, including basic imaging, radiopharmaceuticals, relevant organ systems, pediatrics, oncology, quality control and safety, and more. Key Features *High-quality planar images, SPECT images, and PET-CT images reflect the types of images that you can expect to see on exams.*Multiple-choice questions and extended matching questions have corresponding answers with explanations of not only why one answer is correct, but also why other options are incorrect.*Questions are divided according to the Core Exam Study Guide, so you can work on particular topics as needed.* Answers include brief discussions of differential diagnosis and high-yield tables for additional quick review.* References are provided for every question, helping you further your knowledge when you want to delve more deeply into a particular topic.*An ideal reference and review tool for residents, fellows, practicing radiologists, and those preparing for Maintenance of Certification.Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features such as:*Complete content with enhanced navigation*Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web*Cross-linked pages, references, and more for easy navigation*Highlighting tool for easier reference of key content throughout the text* Ability to take and share notes with friends and colleagues*Quick reference tabbing to save your favorite content for future use

A tactical guide for radiologists and nuclear medicine physicians, Diagnostic Imaging: Nuclear Medicine, Second Edition is practical, easy-to-use, and in-touch with the realities of multimodality diagnostic imaging. This comprehensive yet accessible reference addresses the most appropriate nuclear medicine options available to answer specific clinical questions within the framework of all imaging modalities. Sweeping updates include a complete reorganization, new differential diagnoses based on findings, and new chapters on physics and Nuclear Regulatory Commission guidelines. User-friendly bulleted text and a uniform chapter layout allow fast and effortless access to the crucial knowledge you need!

In 194 cases featuring over 450, high-quality images, Nuclear Medicine and PET/CT Cases provides a succinct review of clinically relevant cases covering the full range of nuclear medicine. Cases are grouped into sections including: Nuclear CNS Imaging, Nuclear Inflammation/Infection Imaging, Ventilation/Perfusion Lung Scintigraphy, Pediatric Nuclear Medicine, Cardiac Imaging, Bone Scintigraphy, PET/CT in Oncology, General Oncologic Imaging, Thyroid and Parathyroid, Radionuclide Therapy and Pre-Therapy Evaluation, Liver, Spleen and Biliary Tract, Gastrointestinal Tract, Renal Scintigraphy. Part of the Cases in Radiology series, this book follows the easy-to-use format of question and answer in which the patient history is provided on the first page of the case, and radiologic findings, differential diagnosis, teaching points, next steps in management, and suggestions for furthering reading are revealed on the following page. This casebook is an essential resource for radiology residents and practicing radiologists alike.

Nuclear Oncology a contemporary narrative of the role of nuclear medicine in oncology with an emphasis on SPECT/CT and PET/CT with additional comments when appropriate on the potential application of PET/MR and to a lesser degree, targeted radionuclide therapy. This book focuses on the use of radionuclides in the diagnosis and treatment of malignant diseases. It describes relevant approved and investigational clinical applications, instrumentation & technology, chemistry and practical clinical issues in nuclear oncology. The basic science and current research topics of nuclear oncology are addressed in separate chapters. Nuclear medicine has become an essential component to all phases of the management of the patient with a malignant tumor and in some cases, even benign neoplasms. The standard of practice for many tumors requires PET/CT imaging at various stages of diagnosis and management. In addition to clinical applications, ongoing investigational efforts, which more and more involve multi-institutional protocols, are also presented. Features:;*;Focuses on the use of radionuclides in the diagnosis and treatment of malignant diseases;*;Emphasizes SPECT/CT and PET/CT with additional emphasis on the potential application of PET/MR;*;Describes relevant approved and investigational clinical applications, instrumentation & technology, chemistry and practical clinical issues in nuclear oncology;

This book, now in its third edition, aims to promote a deeper understanding of the scientific and clinical basis of nuclear medicine and the new directions in medical imaging. The new edition has been revised and updated to reflect recent changes and to ensure that the contents are in line with likely future directions. The book starts by providing essential information on general pathophysiology, cell structure and cell biology as well as the mechanisms of radiopharmaceutical localization in different tissues and cells. The clinical applications of nuclear medicine are then presented in a series of chapters that cover every major organ system and relate the basic knowledge of anatomy, physiology and pathology to the clinical utilization of various scintigraphic modalities. The therapeutic applications of nuclear medicine are discussed in a separate chapter, and the final chapter is devoted to the biologic effects of ionizing radiations, including radiation from medical procedures.

This book explains clearly and in detail all aspects of radiation protection in nuclear medicine, including measurement quantities and units, detectors and dosimeters, and radiation biology. Discussion of radiation doses to patients and to embryos, fetuses, and children forms a central part of the book. Phantom models, biokinetic models, calculations, and software solutions are all considered, and a further chapter is devoted to quality assurance and reference levels. Occupational exposure also receives detailed attention. Exposure resulting from the production, labeling, and injection of radiopharmaceuticals and from contact with patients is discussed and shielding calculations are explained. The book closes by considering exposure of the public and summarizing the "rules of thumb" for radiation protection in nuclear medicine. This is an ideal textbook for students and a ready source of useful information for nuclear medicine specialists and medical physics experts.

For decades this classic reference has been the book to review to master the complexities of nuclear-medicine physics. Part of the renowned "The Basics series of medical physics books", "Nuclear Medicine Physics" has become an essential resource for radiology residents and practitioners, nuclear cardiologists, medical physicists, and radiologic technologists. This thoroughly revised Seventh Edition retains all the features that have made "The Basics series" a reliable and trusted partner for board review and reference. Inside this new edition you'll find: more than 100 new and revised illustrations that underscore difficult concepts; expanded review questions at the end of each chapter - with detailed answers at the end of the book - to help you master the material; key points at the end of each chapter that serve as helpful reminders of the principal points; concise text that clearly explains all the pertinent concepts in nuclear medicine physics; essential mathematical equations that shed further light on key concepts; and, five appendices that elaborate on specific topics, such as physical characteristics of radionuclides and CGS and SI Units.

Diagnostic Imaging for the Emergency Physician, written and edited by a practicing emergency physician for emergency physicians, takes a step-by-step approach to the selection and interpretation of commonly ordered diagnostic imaging tests. Dr. Joshua Broder presents validated clinical decision rules, describes time-efficient approaches for the emergency physician to identify critical radiographic findings that impact clinical management and discusses hot topics such as radiation risks, oral and IV contrast in abdominal CT, MRI versus CT for occult hip injury, and more. Diagnostic Imaging for the Emergency Physician was awarded a 2011 Prose Award for Excellence for the best new publication in Clinical Medicine.

Nuclear Medicine will enable you to make quick diagnoses and sound clinical decisions. Features of Nuclear Medicine: * Numerous high-resolution radiographs reflect the latest nuclear imaging technology * A variety of common and uncommon presentations cover everything from Alzheimer's and dementia to vesicoureteric reflux * The newest Nuclear Regulatory Commission (NRC) cases and helpful pearls for identifying unknown whole body cases RadCases All the key Radiology cases for your rounds, rotations, and exams - in print and online! RadCases contains cases selected to simulate everything that you'll see on your rounds, rotations, and exams. RadCases also helps you identify the correct differential diagnosis for each case - including the most critical. RadCases covers: * Cardiac Imaging * Interventional * Radiology * Musculoskeletal Radiology* Neuro Imaging * Thoracic Imaging * Pediatric Imaging * Gastrointestinal Imaging * Breast Imaging * Nuclear Medicine* Ultrasound Imaging* Head and Neck Imaging * Genitourinary Imaging Each RadCases title features 100 carefully selected, must-know cases documented with clear, high-quality radiographs. The organization provides maximum ease of use for self-assessment. Each case begins with the clinical presentation on the right-hand page; simply turn the page for imaging findings, differential diagnoses, the definitive diagnosis, essential facts, and more. Each RadCases title includes a scratch-off code that allows 12 months of access to a searchable online database of all 100 cases from the book plus an additional 150 cases in that book's specialty - 250 cases in total! Learn your cases, diagnose with confidence and pass your exams. RadCases.

Praise for the first edition:Recommend[ed]...for novices and masters alike. It will improve the reader's breadth of knowledge and ability to make sound clinical decisions. - Clinical Nuclear Medicine Ideal for self-assessment, the second edition of Case-Based Nuclear Medicine has been fully updated to reflect the latest nuclear imaging technology, including cutting-edge cardiac imaging systems and the latest on PET/CT. Each chapter is packed with high-quality images that demonstrate the full-range of commonly encountered disease manifestations as seen in the practice of nuclear medicine. The lavishly illustrated cases begin with the clinical presentation and a concise patient history followed by imaging findings, differential diagnoses, the definitive diagnosis and follow-up information, a brief discussion of the background for each diagnosis, and a list of pearls and pitfalls. Features: * Comprehensive coverage of everything from single photon emission computed tomography to PET/CT imaging * Cases presented as 'unknowns' enable readers to develop their own differential diagnoses - just like on the exam * Over 400 high-resolution images, including full-color PET/CT and cardiac scintigraphic images, document the cases * Numerous tips, tricks, pearls, and pitfalls highlight key points at the end of each chapter * A scratch-off code provides 12 months of access to RadCases, a searchable online database of 250 must-know nuclear medicine cases This user-friendly atlas is an essential resource for all residents and fellows in radiology and nuclear medicine as they review for exams and prepare for rounds. Clinicians will find the succinct presentation of cases an invaluable quick reference in daily practice.

Nuclear Medicine Technology Study Guide presents a comprehensive review of nuclear medicine principles and concepts necessary for technologists to pass board examinations. The practice questions and content follow the guidelines of the Nuclear Medicine Technology Certification Board (NMTCB) and American Registry of Radiological Technologists (ARRT), allowing test takers to maximize their success in passing the examinations. The book is organized by sections of increasing difficulty, with over 600 multiple-choice questions covering all areas of nuclear medicine, including radiation safety; radionuclides and radiopharmaceuticals; instrumentation and quality control; patient care; and diagnostic and therapeutic procedures. Detailed answers and explanations to the practice questions follow. Supplementary chapters will include nuclear medicine formulas, numbers, and a glossary of terms for easy access by readers. Additionally, test-taking strategies are covered.

Nuclear medicine is an important component of modern medicine. This easy-to-use book is designed to acquaint readers with the basic principles of nuclear medicine, the instrumentation used, the gamut of procedures available, and the basis for selecting specific diagnostic or therapeutic procedures and interpreting results. After an introductory chapter on the history, technical basis, and scope of nuclear medicine, a series of chapters are devoted to the application of nuclear medicine techniques in the different body systems. In addition, the use of nuclear medicine methods within oncology is carefully examined, covering diagnosis, staging, assessment of treatment response, radiotherapy planning, and the sentinel node technique. The book concludes with a chapter devoted to nuclear medicine therapy. This practical and up-to-date guide to nuclear medicine is ideal for beginners and will also help professionals who need to retrieve useful information rapidly.

The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. This up-to-date, comprehensive book, written by world-renowned experts, discusses the basic principles of radionuclide therapy, explores in detail the available treatments, explains the regulatory requirements, and examines likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the role of the therapeutic nuclear physician in coordinating a diverse multidisciplinary team, which is central to the safe provision of treatment.