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Handbook of Targeted Cancer Therapy and Immunotherapy

Daniel D. Karp, Gerald S. Falchook
e altri

editore: Wolters Kluwer Health

pagine: 520

Designed for quick, everyday reference, Handbook of Targeted Cancer Therapy and Immunotherapy, 3rd Edition, includes clinical trial results of more than 250 state-of-the-art targeted therapy and immunotherapy agents, providing a practical, intuitive, colorful overview of this rapidly advancing field. Comprehensive yet concise, this easy-access resource by Drs. Daniel D. Karp, Gerald S. Falchook, and JoAnn D. Lim, helps you navigate through the newest research reports and apply the most recent discoveries as they pertain to specific tumor types, actionable molecular targets, and clinical performance of investigational targeted agents and combinations of agents.  This handbook presents information distilled by dozens of translational research clinicians and other healthcare experts with hundreds of years of cumulative experience in the revolutionary area of genomically based precision oncology.  Covers cancer targets—phase 1, 2, and 3 trials and preliminary results, as well as approved therapies.  Includes sections on Molecular Targets and Pathways, and Targeted and Immunotherapy Agents.   Contains a section on Carcinogenesis from the Perspective of Targeted Therapy and Immunotherapy, with essential content on biology, immunology, and immunotherapy.  Organizes information by tumor type, pathway, and drug name, so you can approach clinical challenges from any direction.  Highlights FDA approvals throughout.  Pocket-sized and color coded to help you find information quickly and easily.  Enrich Your eBook Reading Experience  Read directly on your preferred device(s), such as computer, tablet, or smartphone.  Easily convert to audiobook, powering your content with natural language text-to-speech. 
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Cancer Chemotherapy: Basic Science to the Clinic

Gary S. Goldberg, Rachel Airley

editore: Wiley-Blackwell

pagine: 305

Provides a clear and accessible summary of all stages and aspects of the discovery, design, development, validation and clinical use of anticancer drugs This new edition provides an update on the current state of the art of cancer chemotherapy and clinical practice and presents new pipeline anticancer agents and promising therapeutic strategies that are emerging alongside new breakthroughs in cancer biology. Its unique approach enables students to gain an understanding of the pathological, physiological, and molecular processes governing malignancy, while also introducing the role of health professionals and scientists in the research and treatment of cancer. Invaluable for its clarity and accessibility, Cancer Chemotherapy: Basic Science to the Clinic, 2nd Edition offers complete coverage of the scientific and clinical aspects of the creation, development, and administration of drugs or drug regimens used in the treatment of the disease. Chapters look at: cancer epidemiology and histopathology; carcinogenesis; current research; tumor hypoxia; antiangiogenic and antivascular agents; protein kinase and Ras blockers; new targets associated with development such as Hedgehog and Wnt signaling; stem cells; immunotherapy and oncolytic viruses; and more. Presents a clear, accessible, and comprehensive approach to cancer chemotherapy from basic science to clinical practice Offers a major update that reflects the latest developments in personalized chemotherapy Provides in-depth coverage of advances in biomarker diagnostics Includes new chapters/sections on bioinformatics and the ‘omic sciences’; pharmaceutical strategies used to achieve tumor-selective drug delivery; and cancer cell autophagy Combines descriptions of both clinical protocol and explanations of the drug design process in one self-contained book Features numerous diagrams and illustrations to enhance reader understanding Aimed at upper undergraduate, graduate, and medical students, Cancer Chemotherapy: Basic Science to the Clinic, 2nd Edition is also an excellent reference for health professional, especially clinicians specializing in Clinical Oncology, and their patients who want to gain an understanding of cancer and available treatment options.
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Essentials of Interventional Cancer Pain Management

a cura di Amitabh Gulati, Vinay PuttanniahBrian M. BruelJoseph C. HungWilliam S. Rosenberg
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editore: Springer International Publishing AG

pagine: 530

This text provides a comprehensive review and expertise on various interventional cancer pain procedures. The first part of the text addresses the lack of consistency seen in the literature regarding interventional treatment options for specific cancer pain syndromes. Initially, it discusses primary cancer and treatment-related cancer pain syndromes that physicians may encounter when managing cancer patients. The implementation of paradigms that can be used in treating specific groups of cancer such as breast cancer, follows. The remainder of the text delves into a more common approach to addressing interventional cancer pain medicine. After discussing interventional options that are commonly employed by physicians, the text investigates how surgeons may address some of the more severe pain syndromes, and covers the most important interventional available for our patients, intrathecal drug delivery. Chapters also cover radiologic options in targeted neurolysis and ablative techniques, specifically for bone metastasis, rehabilitation to address patients’ quality of life and function, and integrative and psychological therapies.  Essentials of Interventional Cancer Pain Management globally assesses and addresses patients’ needs throughout the cancer journey. Written by experts in the field, and packed with copious tables, figures, and flow charts, this book is a must-have for pain physicians, residents, and fellows.
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Cancer Chemotherapy, Immunotherapy and Biotherapy

Bruce A. Chabner, Dan L. Longo

editore: Lippincott Williams and Wilkins

pagine: 640

Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Thoroughly revised and reformatted, the sixth edition of Cancer Chemotherapy, Immunotherapy and Biotherapy reflects recent significant changes in cancer treatment. This newly streamlined edition contains full-color illustrations, more tables for quick reference, and new immunotherapy and molecular targeted therapy content that brings you fully up to date with the state of the art in all current cancer therapies. Provides thorough, comprehensive coverage of the scientific and clinical aspects of immunotherapy, biotherapy, and chemotherapy. Includes significantly expanded information on immunotherapy and molecular targeted therapy, as well as the latest information on all drugs and biological agents-their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. Features a new, full-color format, a newly streamlined presentation. and more tables and figures throughout for quick access to high-yield information. Explains the rationale for use of drugs in specific schedules and combinations and offers guidelines for dose adjustment in specific situations. Enrich Your eBook Reading Experience with Enhanced Video, Audio and Interactive Capabilities! Read directly on your preferred device(s), such as computer, tablet, or smartphone Easily convert to audiobook, powering your content with natural language text-to-speech Adapt for unique reading needs, supporting learning disabilities, visual/auditory impairments, second-language or literacy challenges, and more
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A Beginner's Guide to Targeted Cancer Treatments

Elaine Vickers

editore: Wiley-Blackwell (an imprint of John Wiley & Sons Ltd)

pagine: 360

The accessible guide to the principles behind new, more targeted drug treatments for cancer Written for anyone who encounters cancer patients, cancer data or cancer terminology, but have no more than a passing knowledge of cell biology. A Beginner's Guide to Targeted Cancer Treatments provides an understanding of how cancer works and the many new treatments available. Using over 100 original illustrations, this accessible handbook covers the biology and mechanisms behind a huge range of targeted drug treatments, including many new immunotherapies. Dr Vickers translates a complex and often overwhelming topic into something digestible and easily understood. She also explains what cancer is, how it behaves and how our understanding of cancer has changed in recent years. Each chapter takes the reader through how new cancer drugs work and their benefits and limitations. With the help of this book, readers will be able to better understand more complex, in-depth articles in journals and books and develop their knowledge. This vital resource: Offers the latest insights into cancer biology Provides a broad understanding of how targeted cancer treatments work Describes many of the new immunotherapy approaches to cancer treatment, such as checkpoint inhibitors and CAR-modified T cells Helps readers feel confident discussing treatment options with colleagues and patients Provides an overview of which treatments are relevant to each of the most common solid tumours and haematological cancers, and the rationale behind them Demystifies the jargon terms such as the EMT, cancer stem cells, monoclonal antibodies, kinase inhibitors, angiogenesis inhibitors etc. Explains the resistance mechanisms to many new treatments, including issues such as the way cancer cells diversify and evolve and the complex environment in which they live
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Drug Information Handbook for Oncology

Diedra L. Bragalone

editore: Lexi-Comp,U.S.

pagine: 2446

The Lexicomp Drug Information Handbook for Oncology supports the needs of oncology professionals involved in prescribing, preparing, and administering therapy. This handbook provides healthcare professionals with vital information on antineoplastic agents, ancillary medications, combination chemotherapy regimens, and dosing protocols. Oncology drug monographs contain concise fields of pharmacology detail, including a Combination Regimens field in specific monographs that provides references to applicable chemotherapy regimens. The Special Topics section reviews cancer-related issues, such as the management of EGFR inhibitor toxicities: dermatologic, ocular, and gastrointestinal; venous thromboembolism in the cancer patient; chronic pain management (cancer); hospice (end of life) care; palliative care medicine (cancer); hematopoietic stem cell transplantation; management of infections; safe handling of hazardous drugs; and emetogenic potential of antineoplastic agents in children. The Appendix adds valuable information on conversions, renal function tests, comparative drug charts, and laboratory reference values for adults.
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Skeel's Handbook of Cancer Therapy

Olivier Rixe, Roland T. Skeel
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editore: Lippincott Williams and Wilkins

pagine: 832

For more than 30 years, Skeel's Handbook of Cancer Therapy (formerly Handbook of Cancer Chemotherapy) has been the resource of choice for current, reliable information on cancer treatment for most adults. The 9th Edition reflects recent significant advances in the systemic treatment of cancer, including innovations in immunotherapy, oncology genomics, and molecular targeted therapy. An invaluable reference for all levels of physicians, nurses, and allied health professionals who provide care to cancer patients, this bestselling guide combines the most current rationale and the details necessary to safely administer pharmacologic therapy, offering a balanced synthesis between science and clinical practice.* A new chapter on the Biologic Basis of Molecular Targeted Therapy, as well as a state-of-the-art review of the current development and use of novel immunotherapeutics, bring you up to date with the rationale and use of these newer agents in cancer treatment.*Completely updated throughout to reflect current best practices, including primary indications, usual dosage and schedule, special precautions, and expected toxicities for dozens of new drugs and biologic agents.* New contributors provide a fresh perspective on timely topics in cancer treatment and care.* An updated section on supportive care reflects this essential aspect of the oncology team's focus.*Regularly updated Inkling content keeps you current with drug profiles and new immunotherapy advances.Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like:*Complete content with enhanced navigation*Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web*Cross-linked pages, references, and more for easy navigation*Highlighting tool for easier reference of key content throughout the text* Ability to take and share notes with friends and colleagues*Quick reference tabbing to save your favorite content for future use
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Antimicrobial Chemotherapy

Guy Thwaites, Mark H. Wilcox
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editore: Oxford University Press

pagine: 450

Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents.The fully revised and updated seventh edition of Antimicrobial Chemotherapy is an essential guide to the principles of antimicrobial chemotherapy, the problem of resistance and its control through policies, antimicrobial stewardship and surveillance. The book provides an aid to informed, rational prescribing for common bacterial, fungal, parasitic and viral infections. Divided in five parts, the book cover issues specific to both the developed and developing world. Part 1 'General property of antimicrobial agents' discusses mechanisms of action and resistance to antibacterial, antifungal antiprotozoal, antiviral, and antiviral agents. Part 2 'Resistance to antimicrobial agents' provides guidance about the problem of resistance, mechanisms of acquired resistance and genetics of resistance. Part 3 'General principles of usage of antimicrobial agents' analyses the use of the laboratory, general principles of the treatment of infection, dosing in special groups (extremes of age, pregnancy, obesity), safe prescribing, prophylaxis and the role of policies in antimicrobial stewardship. Part 4 'Therapeutic use of antimicrobial agents' provides advice about the treatment of common infections which are described by anatomical. There are also chapters on the management of mycobacterial disease, viral infections, HIV/AIDS and parasitic infections. The final part of the book analyses the development and marketing of antimicrobial drugs.This seventh edition of Antimicrobial Chemotherapy continues to be a valuable resource for undergraduates and graduates requiring a thorough grounding in the scientific basis and clinical application of these drugs.
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Il dolore oncologico

Sebastiano Mercadante

editore: Pacini Editore

pagine: 119

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Treatment of Cancer

Karol Sikora, Pat Price

editore: CRC Press Inc

pagine: 871

Treatment of Cancer, Sixth Edition is a multi-authored work based on a single theme-the optimal treatment of cancer. A comprehensive guide to modern cancer treatment, it supports an integrated approach to patient care including radiotherapy, chemotherapy and surgery. The sixth edition has been completely updated to create a useful, practical guide focused on the management of individual tumour types. The characteristic didactic approach to patient care of previous editions is retained, but now with greater consideration to the options available. This book is a valuable resource for trainees, oncologists, radiation oncologists, surgical oncologists, and haematologists.
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La qualità di vita dopo il cancro. Aggiornamenti teorici e strumenti di intervento nella lungosopravvivenza oncologica

Barbara Muzzatti, Maria Antonietta Annunziata

editore: Il Pensiero Scientifico

pagine: 228

Il volume propone una riflessione multidisciplinare sul fenomeno della lungosopravvivenza oncologica che oggi riguarda un nume
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Trattamenti omeopatici di supporto in oncologia

Jean-Claude Karp, François Roux

editore: Edra

pagine: 36

Sia che si pratichi l'allopatia, sia che si pratichi l'omeopatia, la qualità di vita dei pazienti oncologici deve essere oggetto di attenzione da parte del medico. A questo proposito, i trattamenti di supporto devono essere somministrati con la stessa attenzione riservata ai trattamenti antitumorali specifici, per prevenirne al meglio gli effetti collaterali. In questo contesto l'omeopatia, che non può in alcun caso sostituirsi ai trattamenti convenzionali, si integra nell'ambito di una presa in carico multidisciplinare. La terapia omeopatica ci permette di fornire una risposta a molti problemi indotti dalla malattia oncologica o dai suoi trattamenti. In questo volume, gli autori forniscono un prezioso e aggiornato strumento di riferimento per poter affrontare il follow-up dei pazienti sottoposti a trattamento oncologico attraverso schede di facile consultazione, con una presentazione farmacologica di ciascun farmaco antitumorale, seguita dalla descrizione dei principali medicinali omeopatici indicati per gli effetti collaterali incontrati abitualmente e l'indicazione del trattamento da instaurare al più presto, se possibile prima di iniziare la chemioterapia.
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Oncology in Primary Care

Michal Rose

editore: Lippincott Williams and Wilkins

pagine: 455

Oncology in Primary Care is for primary care clinicians who need practical and concise information on caring for their patients with cancer. Written in an easy-to-browse format, chapters cover risk factors, prevention, screening, prognosis, and surveillance strategies - valuable information that helps primary care clinicians advise their patients regarding therapeutic and end-of-life decisions and become true partners in the care of their patients with cancer. Each chapter also includes an abundance of figures and tables to help clinicians find quick answers to questions commonly encountered in the primary care setting. Plus, a companion website is available allowing easy accessibility to the content. It includes a glossary of common cancer-related terms and an annotated list of internet and community resources for cancer care. It provides rapid access to essential information needed to assist in the treatment of complications of cancer therapy. It emphasizes prognosis, long-term effects of therapy, survivorship, and surveillance to help the primary care clinician manage co-morbid conditions and advise patients regarding therapeutic and end-of-life decisions. It includes access to full text and image bank online.
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Cancer Immunotherapy

Tyler J. Curiel

editore: Springer-Verlag New York Inc.

pagine: 496

This work will provide a historical perspective on tumor immunotherapy, discuss fundamental mechanisms of failed tumor rejection, look at passive strategies to boost anti-tumor immunity, as well as have an in-depth look at active strategies to boost anti-tumor immunity.
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Perry's The Chemotherapy Source Book

Michael C. Perry

editore: Lippincott Williams and Wilkins

pagine: 848

"Perry's The Chemotherapy Source Book", now in its fifth edition, provides information on the choice of chemotherapeutic agents, the use of combination chemotherapy, and the toxicity of individual drugs. Organized by site, this is the only book of its kind to focus strictly on the clinical practice of chemotherapy, and is meant to serve as a "one-stop shop" for information on choice of chemotherapeutic agents, treatment outlines, grading of side effects, and dose modification.
90,00 85,50

Terapie orali in oncologia

Sandro Barni, Luciano Frontini
e altri

editore: Elsevier

pagine: 72


Terapie palliative in oncologia. L'utilizzo di tecniche sub-invasive

Beniamino Palmieri

editore: Tecniche Nuove

pagine: 334

Questo libro descrive l'area terapeutica comprendente le cure palliative in campo oncologico esercitate con tipi diversi di strumenti scarsamente invasivi quali: radiofrequenze; elettroterapia ed elettrochemioterapia; crioterapia; laser terapia per infissione con fibra ottica della neoplasia; fototerapia con coloranti radiosensibili; infiltrazione intratumorale di principi attivi, chemioterapici, immunomodulanti; ipertermia in senso generale, locoregionale, focale; terapia locoregionale; terapia genica; terapia con anticoagulanti. L'autore passa in esame le diverse metodologie terapeutiche descrivendone i principi, le apparecchiature utilizzate e le modalità d'azione e riportando i lavori scientifici e le casistiche che ne descrivono i risultati. Si inizia con l'esame della risposta dei malati alle radiofrequenze in termini di riduzione della dimensione o distruzione di vari tipi di tumore, ricavando quindi linee di indirizzo sull'uso di questa tecnica. Si procede quindi passando in rassegna le altre varie tecniche e i possibili campi di azione. L'obiettivo è cercare di ottenere un miglioramento della qualità di vita del malato oncologico ed eventualmente anche un suo prolungamento. Il testo è rivolto a medici in generale e in particolare a operatori sanitari come palliativisti, anestesisti che lavorano nella terapia del dolore, personale degli hospice o che opera sul territorio nella terapia di malati terminali.
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