Oncologia

Designed for quick reference, this handbook provides easily accessible information on the specific drugs and treatment regimens used in cancer chemotherapy. This updated Second Edition includes new drugs and combinations of drugs and reflects the increasing use of chemotherapy in combination with radiation and surgery. The first section presents site-specific cancer staging tables, treatment recommendations, and combination chemotherapy regimens and includes chapters on toxicity grading, dose modifications, and precautions. The second section alphabetically lists all current chemotherapeutic agents and provides essential information on each drug, including interactions, toxicity, indications, and dosing. The third section focuses on control of side effects. This edition is also available electronically for handheld computers. See PDA listing for details.

This is a comprehensive survey of the current state-of-the-art in hematopoietic stem cell transplantation for malignant disease. The authors focus on the indications and results of transplantation for acute leukemia, chronic myelogenous leukemia, lymphoma, multiple myeloma, and breast cancer. Special attention is given to transplant-related complications, including the pathophysiology and clinical consequences of acute and chronic GVHD, delayed immune reconstitution leading to infectious complications, and organ damage to the lung and liver. Additional chapters address the sources of stem cells and the effects of graft manipulation used to eliminate residual contaminating tumor cells in autologous transplantation, or to reduce the number of T lymphocytes causing GVHD in allogenic transplantation.

Pediatric CNS Tumors is a detailed review of childhood nervous system tumors with a particular emphasis on biological data and treatment algorithms for each tumor type. Additional detailed information is provided on the recent advances in chemotherapy, radiation and surgery for these tumors.

It is common knowledge that thromboembolic disease is often the earliest manifestation and almost the most frequent complication of cancer. Recent studies have investigated the mechanisms by which cancer causes thrombosis and have emphasized the importance of the coagulation system in angiogenesis and tumor metastasis. Thrombosis and Cancer offers a detailed and authoritative review of the issues involved in the links between thrombosis, hemostasis, and cancer, an association long documented but still not completely understood. This text provides comprehensive and timely coverage of the current knowledge of cancer-associated thrombosis, its pathogenesis, clinical features, prevention, and therapy. It specifically addresses the relationship between hemostatic systems and cancer, thus providing a unique and much needed focus. All of the contributors are acknowledged specialists in their fields and have experience conducting large clinical trials in oncology and thrombosis. Their discussions cover all aspects of the topic, from long-term complications to cancer surgery. With input from specialists in a range of disciplines including hematology, pharmacology, and surgery, this thorough text will be of interest to general practitioners, internists, oncologists, hematologists, and all physicians involved in the management of cancer patients.

Endoanal and endorectal ultrasound represents considerable progress in the field of anorectal imaging. Its importance in the staging of rectal and anal cancer, in identifying perianasto- motic neoplastic recurrences, in defining acute and chronic suppurative disease and in assessing sphincteral anatomical integrity, is now a confirmed reality. The evidence provided by endoanal and endorectal ultrasonography guides the colorectal surgeon in his choice among the various therapeutic approaches and helps in assessing the effects of the treatments applied. The great flexibility and high degree of reliability make this exploratory method an indispensable tool at all stages of the clinical course in the majority of patients with anorectal problems, including the fundamental follow-up stage. The publication of this excellent volume on intraanal and intrarectal ultrasonog- raphy is therefore to be appreciated, especially since it is in the form of an atlas. As we are dealing with imaging, it is particularly appropriate that it is the images that tell the story. Like all important things, this volume does not come out of nothing. It is the result of many years of skilled work by Drs. G.A. Santoro and G. Di Falco and is based on the experience of internationally renowned professional experts. The ten sections of the atlas begin with general information on ultrasonography, gradually progressing to the technical problems of the method and the aspects rela- tive to anorectal tumors.This last section leads to a review of traditional and mod- ern therapeutic possibilities.

This is the sixth volume in the WHO series on histological and genetic typing of human tumours. Each entity is extensively discussed with information on clinicopathological, epidemiological, immunophenotypic and genetic aspects of these diseases.

'Pathology and Genetics of Tumours of the Urinary Systems and Male Genital Organs' is the sixth volume in the new WHO series on histological and genetic typing of human tumours, covering tumours of the kidney, the urinary system, the prostate, the testis and paratesticular tissue and the penis.

This book provides an overview of recent advances in radiation oncology, many of which have originated from physics and engineering sciences. The new technologies in this field have a complex physical, mathematical and technical background that technical assistants, dosimetrists, and physicians frequently find difficult to comprehend. However, this book is specifically designed to be readily understandable by professionals and students with a medical background as well as by newcomers to radiation oncology from the field of physics. All relevant areas of the subject are covered in detail, including 3D imaging and image processing, 3D treatment planning, modern treatment techniques, patient positioning, and aspects of verification and quality assurance.

An essential reference for all radiologists using Magnetic Resonance Imaging to identify and diagnose pelvic cancer, MRI Manual of Pelvic Cancer provides readers with a working knowledge of current technology and a comprehensive set of images of the various pelvic cancers. The book starts with three introductory chapters focusing on basic pelvic anatomy, imaging, and reporting. The subsequent chapters focus on each of the major types of pelvic cancer using a consistent format to aid diagnosis. Written by internationally renowned authors, the book is an invaluable bench reference for all those required to report on MR examinations.