Oncologia

Cancer in Children is an established and highly regarded introduction to paediatric oncology. In a clear and concise way, it covers the aetiology, symptoms, and treatment of cancer in children, the complications that can arise during treatment, and the various outcomes of the illness. This new edition brings together an international group of highly respected editors and contributors to provide evidence-based information on how to investigate and treat the common cancers in childhood. State-of-the-art descriptions of what is basic and essential for management is included; there are new chapters on clinical trials, evidence based practice, the treatment of cancer in less well-resourced countries, stem cell and immunotherapy, other malignant / borderline haematological conditions (myelodysplasia and myeloproliferative disorders), and on imaging. These all reflect important changes in the focus of the speciality in recent years. Aimed at paediatric oncologists, and trainees in oncology and paediatrics, this leading text will also appeal to paediatric nurses, cancer nurses, and paramedical paediatric staff.

The Molecular Biology of Cancer, Stella Pelengaris & Michael Khan This capturing, comprehensive text, extensively revised and updated for its second edition, provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. "Bench to Bedside": A key strength of this book that sets it apart from general cancer biology references is the interweaving of all aspects of cancer biology from the causes, development and diagnosis through to the treatment and care of cancer patients -- essential for providing a broader view of cancer and its impact. The highly readable presentation of a complex field, written by an international panel of researchers, specialists and practitioners, would provide an excellent text for graduate and undergraduate courses in the biology of cancer, medical students and qualified practitioners in the field preparing for higher exams, and for researchers and teachers in the field. For the teaching of cancer biology, special features have been included to facilitate this use: bullet points at the beginning of each chapter explaining key concepts and controversial areas; each chapter builds on concepts learned in previous chapters, with a list of key outstanding questions remaining in the field, suggestions for further reading, and questions for student review. All chapters contain text boxes that provide additional and relevant information. Key highlights are listed below: * An overview of the cancer cell and important new concepts. * Selected human cancers: lung, breast, colorectal, prostate, renal, skin, cervix, and hematological malignancies. * Key cellular processes in cancer biology including (a) traditionally important areas such as cell cycle control, growth regulation, oncogenes and tumour suppressors apoptosis, as well as (b) more highly topical areas of apoptosis, telomeres, DNA damage and repair, cell adhesion, angiogenesis, immunity, epigenetics, and the proteasome. * Clinical oncology: In-depth coverage of important concepts such as screening, risk of cancer and prevention, diagnoses, managing cancer patients from start to palliative care and end-of-life pathways. * Chapters highlighting the direct links between cancer research and clinical applications. * New coverage on how cancer drugs are actually used in specific cancer patients, and how therapies are developed and tested. * Systems Biology and cutting edge research areas covered such as RNA interference (RNAi). * Each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review. * Quotations have been used in each chapter to introduce basic concepts in an entertaining way. * Supported by a dedicated website at www.blackwellpublishing.com/pelengaris We should list the great reviews we got for first edition which are on the back of the 2nd edition: "A capturing, comprehensive, clearly written and absolutely accurate introduction into cancer biology...This book deserves great praise for the readable presentation of this complex field...the true synthesis of bench and bedside approaches is marvelously achieved." Christian Schmidt, Molecular Cell "Chapters address the issues of cancer diagnosis, treatment, and patient care and set the book apart from general molecular biology references...This book is applicable to both graduate and undergraduate students, and in the context of a research laboratory, this book would be an excellent resource as a reference guide for scientists at all levels." V.Emuss, Institute of Cancer Research, London. Also, from the first edition: "Pelengaris, Khan, and the contributing authors are to be applauded. The Molecular Biology of Cancer is a comprehensive and readable presentation of the many faces of cancer from molecular mechanisms to clinical therapies and diagnostics. This book will be welcomed by neophyte students, established scientists in other fields, and curious physicians." -Dean Felsher, Stanford University  

Meet the increasing need for effective brain tumor management with the highly anticipated revision of "Brain Tumors" by Drs. Andrew H. Kaye and Edward R. Laws. Over the past decade, enormous advances have been made in both the diagnosis and the surgical and radiotherapeutic management of brain tumors. This new edition guides you through the latest developments in the field, including hot topics like malignant gliomas, functional brain mapping, neurogenetics and the molecular biology of brain tumors, and biologic and gene therapy. You'll also have easy access to the complete contents online, with links to PubMed and a downloadable image library, at our associated website.

Long established as a staple reference for all radiation oncologists, "Radiotherapy for Head and Neck Cancers: Indications and Techniques" is now in its fourth edition. This completely updated edition presents the state-of-the-art protocols currently used at the MD Anderson Cancer Center and thoroughly explains the principles, nomenclature, and clinical use of intensity-modulated radiotherapy (IMRT). The first section discusses the practical aspects of external beam therapy, brachytherapy, and endocavitary beam therapy and offers guidelines on patient care before and during radiotherapy. The second section provides detailed coverage of site-specific indications and techniques.

* New edition fully includes Grades and Levels of evidence, providing a better idea of what the sum total of existing evidence suggests regarding key topics * Grades and levels of evidence consistently highlighted throughout * Greater number of tables and algorithms ("decision trees") for key decision-making areas * "Scope of concept" introduction to chapters are significantly enhanced, allowing the reader to reference the concepts while reviewing the specific details in the clinically oriented chapters * The only available book with an evidence-based approach covering this specific subject matter in one compendium

"Cancer of the Skin", edited by Drs. Rigel, Robinson, Ross, Friedman, Cockerell, Lim, Stockfleth, and Kirkwood, is your complete, multimedia guide to early diagnosis and effective medical and surgical treatment of melanoma and other skin cancers. Thoroughly updated with 11 new chapters, this broad-based, comprehensive reference provides you with the latest information on clinical genetics and genomics of skin cancer, targeted therapy for melanoma, the Vitamin D debate concerning the risks and benefits of sun exposure, and other timely topics. A new, multi-disciplinary team of contributors and editors comprised of leading experts in this field offers truly diverse perspectives and worldwide best practices.

"Decision Making in Radiation Oncology" is a reference book designed to enable radiation oncologists, including those in training, to make diagnostic and treatment decisions effectively and efficiently. The design is based on the belief that "a picture is worth a thousand words." Knowledge is conveyed through an illustrative approach using algorithms, schemas, graphics, and tables. Detailed guidelines are provided for multidisciplinary cancer management and radiation therapy techniques. In addition to the attention-riveting algorithms for diagnosis and treatment, strategies for the management of disease at individual stages are detailed for all the commonly diagnosed malignancies. Clinical trials that have yielded "gold standard" treatment and their results are documented in the schemas. Moreover, radiation techniques, including treatment planning and delivery, are presented in an illustrative way. This groundbreaking publication is an essential tool for physicians in their daily clinical practice.

Drawn from the content of the new Ninth Edition of Cancer: Principles and Practice of Oncology, this unique publication brings together the basic scientific information on the molecular biology of cancer. The format is designed to be useful both to research scientists interested in the study of cancer and to oncologists who need to understand these new developments that are having a profound impact on the care of patients with cancer. Leading scientists and clinicians in the field of molecular biology and clinical oncology have lent their expertise to this project. The text has been divided into two parts. Part I includes thirteen chapters that deal with the general principles of the molecular biology of cancer that provide the basic framework for an understanding of the behavior of cancer cells. Part II includes an up-to-date description of how this new information has affected the understanding of the biology of 19 of the most common cancers, with an emphasis on how these new findings have been translated to impact the management of cancer patients. This distinctive text provides a single concise source of information for scientists and clinicians in this rapidly developing field.