CRC Press

Endocrinology is a complex specialty that spans a wide range of diseases, disorders, and conditions. The field is now moving toward an increasingly personalized approach to patient management, with a greater focus on mechanisms of disease and biomarkers. Written by internationally renowned specialists, the second edition of Endocrinology in Clinical Practice provides a cutting-edge, problem-orientated approach to the management of clinical problems in endocrinology. Highlights of the new edition include: * An overview of neuroendocrine disease * Strides made by the identification of aryl hydrocarbon receptor-interacting protein mutations in patients with familial isolated pituitary adenomas * The diverse roles of IGF-I * Changes in diagnostic imaging and the increasing use of positron emission tomography * The rapidly increasing incidence of neuroendocrine tumors and their management * Hereditary primary hyperparathyroidism and multiple endocrine neoplasia * Mechanistic and genomic advances related to disorders of calcium regulation and infertility * The endocrinology of aging * Protocols for pituitary function testing With complete updates to existing chapters, the second edition also presents new research data, diagnostic techniques, treatment options, and safety concerns related to existing therapies. This edition offers current guidance and scientifically focused information relevant to a range of clinical problems, making it an essential reference for practicing endocrinologists and specialist clinicians.

The new edition of this authoritative review of the clinical approach to diagnostic and therapeutic obstetric, maternal-fetal and perinatal procedures will be welcomed by all professionals involved in childbirth as a significant contribution to the practice of maternal-fetal medicine and surgical obstetrics.

Ear, Nose and Throat Diseases of the Dog and Cat is the ultimate reference for veterinarians and other professionals trying to diagnose and treat both common and less frequently diagnosed diseases and conditions of the ear, nose and throat. The book is divided into four sections: The Ear, The Nose, The Throat and Surgery of the Ear, Nose and Throat. Each of the first three sections begins by discussing anatomy and physiology and then reviews a wide variety of diagnostic procedures including video-endoscopic examination of the external ear canal, nose and throat, radiography and advanced imaging, and histopathological examination of biopsy samples. Chapters in each of the three sections then provide a detailed and extensive review of the diseases of the pinna, external ear canal, middle ear and inner ear - nasal planum, nasal cavities and sinuses and nasopharynx - pharynx and larynx. The final section opens with a chapter on perioperative management with subsequent chapters that cover surgery of the ear, nose and throat. Extensively referenced, and including more than 750 color illustrations to assist in diagnosis and treatment, the book is an invaluable resource for both veterinarians in training and in practice for the accurate diagnosis and management of diseases of the ear, nose and throat.

The third edition of the bestselling Clinical Trials in Oncology provides a concise, nontechnical, and thoroughly up-to-date review of methods and issues related to cancer clinical trials. The authors emphasize the importance of proper study design, analysis, and data management and identify the pitfalls inherent in these processes. In addition, the book has been restructured to have separate chapters and expanded discussions on general clinical trials issues, and issues specific to Phases I, II, and III. New sections cover innovations in Phase I designs, randomized Phase II designs, and overcoming the challenges of array data. Although this book focuses on cancer trials, the same issues and concepts are important in any clinical setting. As always, the authors use clear, lucid prose and a multitude of real-world examples to convey the principles of successful trials without the need for a strong statistics or mathematics background. Armed with Clinical Trials in Oncology, Third Edition, clinicians and statisticians can avoid the many hazards that can jeopardize the success of a trial.

This new edition of the bestselling Clinical Signs in Small Animal Medicine presents 800 all new color photographs of the highest quality, with detailed captions that focus on key pointers to diagnosis and treatment. The book is organised into chapters by body system, each beginning with a list of 'Clinical Pearls'. These amusing and accurate key points will be invaluable when considering conditions or highlighting common concerns. Within each chapter, the superb photographs of real cases are annotated with brief, key information that provides a succinct and useful reminder of lessons learned.

A powerful tool that can be employed in a wide variety of disease processes, cytology in small animals has gained increased recognition and clinical application. Small Animal Cytologic Diagnosis presents clinically applicable information about the use of cytology and indicates when advanced diagnostic testing can be beneficial to diagnose underlying disease processes. The book discusses the pathophysiology of inflammation, cancer biology and comparisons to histology to help readers fully comprehend the cytologic changes that can occur with inflammation and neoplasia. Also covered are some of the limitations and advantages of cytology compared to histopathology. The book includes tissue-specific chapters focusing on diseases of a particular area, always in comparison to normal tissue. Each of these chapters concludes with various cases that include information on signalment, history, pertinent laboratory data, specimen images, final outcome and the underlying pathology causing the cytologic lesions, when possible. With more than 1300 superb illustrations, this comprehensive resource provides ample practical information for students as well as practicing veterinarians.

Molecular Detection of Animal Viral Pathogens presents expert summaries on state-of-the-art diagnostic approaches for major animal viral pathogens, with a particular emphasis on identification and differentiation at the molecular level. Written by specialists in related research areas, each chapter provides a concise overview of an individual virus or group concerning its Classification Morphology Genome organization Epidemiology Clinical features Diagnosis Sample collection and preparation procedures Molecular detection protocols Each chapter also discusses future prospects or further research requirements for streamlining the identification and epidemiological tracking of the virus concerned. With broad coverage presented in a concise format, Molecular Detection of Animal Viral Pathogens is an essential reference for both beginning and experienced laboratory scientists as well as students of virology. It also offers an indispensable guide applicable to medical, veterinary, and industrial settings that are dependent on speedy turnarounds, extreme sensitivity, and exquisite specificity of virological testing for decision making and disease prevention.

Prior to publication of the first edition of Clinical Medicine of the Dog and Cat, no other comprehensive small animal veterinary medicine book existed with a comparable amount of relevant illustrated material. This new third edition continues and expands on the revolutionary approach of the previous two editions, now including more than 1,850 highly valuable clinical colour photographs, diagrams, and tables. The third edition of this book has been completely revised and updated. The book is now divided into five color-coded sections - General Approach, Disease of Specific Organ Systems, Multisystemic Disorders, Elements of Therapy and Case Studies. As with the first and second editions of this book the overriding principle of succinct, yet comprehensive text presented in a clear format with an abundance of good quality images remains. Section I: General Approach is completely new and covers medical history and client communication, and common clinical problems. Section II: Specific Organ Systems is organized by body system with chapters structured in a systematic manner that include the definition for each disorder, its causes, clinical features, differential diagnoses, diagnostic methodology, treatment and prognosis, providing readers with easy access to important clinical information. New to this section are chapters covering diseases of the oral cavity and teeth, approach to thoracic radiographs, approach to abdominal radiographs, and disorders of hemostasis. Section III: Multisystemic Disorders covers revised and updated chapters including clinical toxicology, infectious diseases, and immunologic disorders. Section IV: Elements of Therapy covers therapies such as fluid therapy, pain management, nutrition of the critically ill dog and cat and a new chapter on management of the obese dog or cat. Section V: Case Studies includes over 25 case studies that enable the reader to relate the knowledge gained in the book to clinical cases seen in practice. Written by board-certified experts with several case contributions by clinicians in advanced phases of resident training, topics were carefully selected to make this a valuable resource to the general practitioner and also to small animal interns and veterinary students.

Arthropod-borne Infectious Diseases of the Dog and Cat is an invaluable resource for information on the clinical presentation, pathogenesis, diagnosis and treatment of the major arthropod-borne diseases of dogs and cats. Also discussed is an array of diagnostic techniques routinely available to veterinarians presented with these diseases. Illustrated in colour throughout, the book incorporates photographs of clinical cases, haematology, cytology and gross and microscopic pathology, which help understand the diagnosis and treatment of these diseases. While its fundamental structure remains unchanged, this new edition adds a chapter on haemoplasma infections as well as a revised chapter on rare, and particularly viral, arthropod-borne diseases of dogs and cats. This new edition is fully updated to reflect the changes and geographical spread of the diseases covered. New for this edition is the inclusion of a series of clinical case studies providing relevant examples of the diseases discussed. In short, the book provides an accessible guide to arthropod-borne infectious disease for veterinarians both in practice and training. With the effects of climate change and increasing international pet travel, this book is a useful addition to every small animal practitioner's library.

100 Hand Cases provides a clinical write-up of 100 typical cases from two globally recognized authorities who cross over between plastic surgery and orthopedics, the two specialties dedicated to training hand surgeons. The cases in this book share a concise approach consisting of: * A description of the problem * Key anatomy * Workup * Treatment * Alternatives * Principles and clinical pearls * Pitfalls * Classic references related to the case Full-color photographs and radiographs are included in each case, as well as a discussion of the authors' preferred treatment solution. Presented in a highly templated, high-yield format, 100 Hand Cases is an ideal quick reference for students and trainees preparing for clinics and the operating room, as well as busy surgeons in need of a brief reminder on key information.