Academic Press Inc

"Principles of Molecular Virology, Third Edition" provides an essential introduction to modern virology in a clear and concise manner. It is a highly enjoyable and readable text with numerous illustrations that enhance the reader's understanding of important principles. This edition has been updated and revised with new figures and text. It also includes a CD-ROM with material that complements the text. The CD-ROM includes interactive tutorials, virtual experiments and multiple-choice questions. New to 3rd Edition are: Viruses and Apoptosis (Chapter 6); Bacteriophages and Human Disease (Chapter 7); learning objectives for each chapter; pronunciation section in Glossary and abbreviations section (Appendix 1); Key events in the history of virology (Appendix 3); and, addition of colour in text and figures to enhance understanding of key points. It includes a CD containing interactive learning resources to complement text, e.g. tutorials, MCQ's, Virtual experiments, PPT slide set containing lecture notes. A different CD is included with standard and Instructor's edition. It also includes a Virology on-line section - encourages readers to access the Internet to find further information. It includes self assessment questions at the end of each chapter and classification of Subcellular Infectious agents. It contains approximately 20 per cent new material and is completely revised throughout. It contains over 120 figures.

With the recent changes in the health care industry, surgeons face increasing pressure to devote their time to their clinical activities, thus limiting their research efforts. It is essential that young and creative individuals are encouraged to perform research and are given incentives to participate in research under the mentorship of more experienced research investigators. "Surgical Research" is the first book to include all the information necessary for the surgical scientist to perform a research experiment. The editors have assembled outstanding, expert investigators in multiple surgical fields and asked them to describe how they achieve their research accomplishments. In "Surgical Research", these experts in the field have outlined everything involved in preparing and conducting a research project. Some of the topics covered in the book include how to state a research question, how to review the available information, how to write research protocol, how to obtain grant money for the experiment, how to analyze the data, and how to present the findings. Also discussed are the ethics of animal and human experimentation along with the history and philosophy of surgical research. To continue to advance technologies and surgical methods, research must continually be performed. Potentially great discoveries are being missed because would-be researchers do not know where to start or how to conduct research, and therefore do not even try. This book provides prospective researchers with all the basic steps needed to perform a research experiment in the surgical field. No student, resident, or fellow should start a research project without this book and no senior surgical scientist should be without it occupying a prominent position in the library. Key features include: the first complete compendium detailing the process and procedures to perform surgical research; provides details on and compares various methodologies; a 'must have' resource for the surgical resident, fellow, or scientist; and, includes a listing of resources and web sites to help the researcher even further.

The thalamus is a group of cells placed centrally in the brain that serve a critical role in controlling how both sensory and motor signals are passed from one part of the cerebral cortex to another. Essentially, all information reaching the cerebral cortex and thus consciousness is relayed through the thalamus. The role of the thalamus in controlling the flow of information (such as visual, auditory, and motor) to the cortex has only recently begun to be understood. This book provides an in-depth look at the function of the thalamus and its role as relayer of information to the cerebral cortex. The authors explore how the thalamus controls messages that are passed to the cortex and they introduce the novel suggestion that the thalamus serves a critical role in controlling how messages pass from one part of the cortex to another. "Exploring the Thalamus" is a comprehensive, up-to-date reference for researchers. It discusses problems concerning the function and structure of the thalamus and concludes each chapter with thought-provoking questions regarding future research. Among its key features it: focuses on thalamocortical interrelationships; discusses important problems concerning the function and structure of the thalamus; and concludes each chapter with thought-provoking questions requiring future research.

Brain Plasticity and Epilepsy integrates the latest developments in normal and abnormal neuroplasticity and epilepsy, and considers their implications for understanding the basic mechanisms of normal and pathological behaviors. The chapters are written by leaders in the field, and provide comprehensive coverage of the subject, from molecular neurobiology to behavior. This book will help neuroscientists gain a better understanding of the application of fundamental neuronal mechanisms of plastic change to problems relevant to the diagnosis, treatment, and prevention of human disease, particularly epilepsy.

"Heart Physiology and Pathophysiology, 4E" provides the foundation for the scientific understanding of heart function and dysfunction, and bridges the gap between basic cardiovascular science and clinical cardiology. This comprehensive text covers all the important aspects of the heart and vascular system. The most important and relevant disorders are presented, with emphasis on the mechanisms involved. The first three editions of this book developed a reputation as the leading reference in cardiovascular science for researchers and academic cardiologists. This recent edition has been updated, expanded, and includes a number of new contributors. It has also been remodeled to expand its usage as a text reference for cardiology residents, practicing cardiologists, and graduate students. Key features include: the most comprehensive book available on this topic; clear, concise, and complete coverage of all important aspects of cardiovascular physiology/pathophysiology; completely updated version of the foremost reference on cardiovascular science, including new information on pathophysiology and electrophysiology; and useful tool in bridging the gap between basic science, pathophysiology, and clinical cardiology.

Psychoneuroimmunology is the study of interactions among behavioral, neural and endocrine, and immunologic processes of adaptation. These two volumes provide a clearly written, extensively referenced summary of some of the behavioral, neural and endocrine regulators of immune responses and immunologically mediated disease processes and of the behavioral and neuroendocrine effects of immune system activity. Several chapters expand upon topics reviewed in earlier editions of this series; most chapters cover active areas of research that have not previously been reviewed. As illustrated in this fourth edition, interdisciplinary research continues to provide evidence that the brain and immune system represent a single, integrated system of defense. It is fully revised and updated fourth edition of the classic reference. It provides a neuroendocrine and immunologic perspective for the behavioral scientist. It provides a behavioral and neuroscience perspective for the immunologist. It helps the reader translate basic science findings into clinically relevant information. It provides the reader with the background for and foundation of integrative research and integrative medicine. It provides an encyclopedic resource for advanced undergraduates and for pre - and post-doctoral students as well as active researchers.

This book describes everything about DNA repeat instability and neurological disorders, covering molecular mechanisms of repeat expansion, pathogenic mechanisms, clinical phenotype, parental gender effects, genotype-phenotype correlation, and diagnostic applications of the molecular data. This updated edition provides excellent updates of these repeat expansion mutations, including the addition of many new chapters, and old chapters rewritten as extensions of the previous edition. This edition also features a CD-ROM containing all of the figures from the book. This book is an invaluable reference source for neuroscientists, geneticists, neurologists, molecular biologists, genetic counsellors and students. It contains contributions by most of the principal research teams in the area, edited by world-renowned leaders. It lays the background for future investigations on related diseases.