Emphasizing the urgent need to clearly understand the underlying cellular and molecular mechanisms involved in COPD, this reference provides an up-to-date perspective on the inflammatory cells, mediators, and molecular pathology of COPD.
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Why More Research into Molecular and Cellular Mechanisms of COPD Is Needed. Inflammation in Lung Parenchyma. Small Airways Disease in COPD. Asthma versus COPD: Cellular and Molecular Differences. Airway Mucus Hypersecretion. Macrophages. Neutrophils. Epithelial Cells. T Lymphocytes. Inflammatory Mediators. Oxidative Stress. Proteinases in COPD. Antiproteases. Corticosteroid Resistance in COPD. Molecular Genetics. Mechanisms of Systemic Effects. Mechanisms of Exacerbations of Chronic Obstructive Pulmonary Disease. Mechanisms of Pulmonary Vascular Changes. Therapeutic Implications and Future Developments
