Diagnosing neurodegenerative diseases can prove particularly intimidating to clinicians, because many times the diagnosis cannot be critically "confirmed" by a simple test. New imaging modalities have advanced to the point of high resolution, morphological, metabolic and functional analysis. Computed tomography, magnetic resonance, nuclear medicine and molecular imaging have recently emerged as outstanding non-invasive techniques for the study of the neurodegenerative disorders. Imaging in Neurodegenerative Disorders covers all the imaging techniques and new exciting methods like new tracers, biomarker, metabolomic and gene-array profiling, potential for applying such techniques clinically, and offers present and future applications as applied to the neurodegenerative disorders with the most world renowned scientists in these fields. This book is an invaluable resource for researchers, clinicians, and trainees in neuroscience, neurology, psychiatry, and radiology.
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SECTION 1: INTRODUCTION ; 1. Epidemiology of neurodegenerative diseases ; 2. Metabolomics of neurodegenerative disorders ; 3. Transcriptome profiling in neurodegenerative disorders ; 4. Health economic considerations in neurodegenerative disorders ; 5. Symptoms of neurodegenerative diseases ; SECTION 2: IMAGING TECHNIQUE ; 6. Computed Tomography ; 7. General principles of Magnetic Resonance Imaging ; 8. Nuclear medicine and radiology ; 9. Molecular imaging and neurodegenerative diseases ; 10. PET imaging in neurodegenerative disorders - evolving techniques and new tracers ; 11. Radiopharmaceuticals for molecular imaging of neurodegenerative diseases ; SECTION 3: NEURODEGENERATION: COGNITION ; 12. Neuroimaging of Alzheimer's disease ; 13. MRI-based imaging of Alzheimer's disease ; 14. Frontotemporal dementia ; 15. Dementia with Lewy Bodies ; 16. Corticobasal Syndrome and Corticobasal Degeneration ; SECTION 4: NUEORREGENERATION: MOVEMENT ; 17. Parkinson's disease: Clinical and Imaging Features ; 18. Progressive Supranuclear Palsy (PSP) ; 19. Imaging in Huntington's disease ; 20. Multiple system atrophy ; SECTION 5: NEURODEGENERATION: STRENGTH ; 21. Amyotrophic Lateral Sclerosis ; SECTION 6: NEURODEGENERATION: COORDINATION ; 22. Spinocerebellar Atrophies ; 23. Imaging in Neurodegenerative Disorder- Friedreich Ataxia ; 24. Neuroimaging in human prion diseases ; SECTION 7: NEURODEGENERATION: PNS\ANS ; 25. Amyloidosis ; 26. Metabolic and toxin related neurodegeneration ; SECTION 8: NEURODEGENERATION: MYELIN ; 27. Demyelinating diseases ; 28. Charcot-Marie-Tooth disease ; 29. Neurodegenerative Disorders of the Basal Ganglia ; SECTION 9: NEURODEGENERATION: TRAUMA ; 30. Clinical benefit of dopamine transporter imaging in movement disorders and dementia ; 31. Neurodegeneration post trauma: Brain ; 32. Neurodegeneration post trauma: spine ; 33. Neurodegeneration post trauma: Peripheral nerves ; SECTION 10: NEUROIMAGING AFTER THERAPY ; 34. Functional imaging of neurosurgery in Parkinson's disease ; 35. Neuroimaging after Cell-Based Therapy
