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Viral Oncology

Basic Science and Clinical Applications

Titolo Viral Oncology
Sottotitolo Basic Science and Clinical Applications
Autori ,
argomento
Editore Wiley-Blackwell (an imprint of John Wiley & Sons Ltd)
Formato
Formato Libro Libro
Pagine 476
Pubblicazione 2010
ISBN 9780470379912
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Clinical oncologists and researchers now have a comprehensive single source of current information on cancer viruses obtained from bench and bedside. This important refernce allows further development of translational approaches for the effective treatment of patients with virus-associated malignancies. The book contains 25 chapters covering basic and clinical aspects of viruses, including HPV, HBV, HCV, polyomaviruses, Kaposi's associated viruses, retroviruses (including HIV-1 associated malignancies), and EBV. Several chapters are devoted to basic science of oncogenic viruses for the study of their pathogenesis, drug development, and employment of viral vectors for vaccine and gene therapy. Clinical materials are embedded within chapters, and there are also complementary, clinically based chapters describing natural courses and treatments.
 

Indice testuale

Foreword. Preface. Contributors. 1 HUMAN PAPILLOMAVIRUS-ASSOCIATED CANCERS (Rachel A. Katzenellenbogen and Denise A. Galloway). 2 MOLECULAR EVENTS ASSOCIATED WITH HUMAN PAPILLOMAVIRUS-INDUCED HUMAN CANCERS (Amy Baldwin and Karl Munger). 3 THE ROLE OF THE HUMAN PAPILLOMAVIRUS E6 ONCOPROTEIN IN MALIGNANT PROGRESSION (Miranda Thomas, David Pim, and Lawrence Banks). 4 JC VIRUS ASSOCIATION WITH BRAIN TUMORS: THE ROLE OF T ANTIGEN AND INSULIN-LIKE GROWTH FACTOR 1 IN DNA REPAIR FIDELITY (Krzysztof Reiss, Kamel Khalili, and Luis Del Valle). 5 INVOLVEMENT OF THE POLYOMAVIRUS, JC VIRUS, IN COLORECTAL CANCER (C. Richard Boland, Luigi Ricciardiello, and Ajay Goel). 6 POSSIBLE ASSOCIATION OF BK VIRUS WITH PROSTATE CANCER (Michael J. Imperiale and Dweepanita Das). 7 ONCOGENIC TRANSFORMATION BY POLYOMAVIRUS LARGE T ANTIGEN (Abhilasha V. Rathi and James M. Pipas). 8 SIMIAN VIRUS 40, HUMAN INFECTIONS, AND CANCER: EMERGING CONCEPTS AND CAUSALITY CONSIDERATIONS (Janet S. Butel). 9 SIMIAN VIRUS 40 AND MESOTHELIOMA (Natalya Baranova and Michele Carbone). 10 MOLECULAR IMMUNOBIOLOGY OF HEPATITIS B-ASSOCIATED VIRAL CANCER (Timothy M. Block and Anand S. Mehta). 11 HEPATITIS B VACCINE AND HEPATOCELLULAR CARCINOMA (Mei-Hwei Chang and Ding-Shinn Chen). 12 PATHOGENESIS OF ACUTE AND CHRONIC HEPATITIS C VIRUS INFECTION (Mark A. Feitelson, Helena M.G.P.V. Reis, Jingbo Pan, and Bill Sun). 13 MOLECULAR MECHANISMS OF HEPATITIS C VIRUS-INDUCED CELLULAR TRANSFORMATION (Donna Sir and Jing-Hsiung James Ou). 14 CLINICAL ASPECTS OF HTLV-1-ASSOCIATED CANCER (Masao Matsuoka). 15 ONCOGENIC POTENTIAL OF THE HTLV-1 TAX PROTEIN (Susan J. Marriott). 16 HIV-1-ASSOCIATED MALIGNANCY: BASIC AND CLINICAL ASPECTS (Melissa Agsalda and Bruce Shiramizu). 17 HIV-RELATED LYMPHOMA (Giulia De Falco, Cristiana Bellan, Stefano Lazzi, and Lorenzo Leoncini). 18 BIOLOGY AND EPIDEMIOLOGY OF HHV-8 (Veenu Minhas and Charles Wood). 19 THE ROLE OF KSHV IN PATHOGENESIS OF KAPOSI'S SARCOMA (Gary S. Hayward, Donald J. Alcendor, and Ravit Arav-Boger). 20 MOLECULAR PATHOBIOLOGY OF EBV INFECTION (Joseph S. Pagano). 21 EPSTEIN-BARR VIRUS AS A PATHOGEN (Wasim A. Dar and Bill Sugden). Index.

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