Wiley-Blackwell (an imprint of John Wiley & Sons Ltd)

The accessible guide to the principles behind new, more targeted drug treatments for cancer Written for anyone who encounters cancer patients, cancer data or cancer terminology, but have no more than a passing knowledge of cell biology. A Beginner's Guide to Targeted Cancer Treatments provides an understanding of how cancer works and the many new treatments available. Using over 100 original illustrations, this accessible handbook covers the biology and mechanisms behind a huge range of targeted drug treatments, including many new immunotherapies. Dr Vickers translates a complex and often overwhelming topic into something digestible and easily understood. She also explains what cancer is, how it behaves and how our understanding of cancer has changed in recent years. Each chapter takes the reader through how new cancer drugs work and their benefits and limitations. With the help of this book, readers will be able to better understand more complex, in-depth articles in journals and books and develop their knowledge. This vital resource: Offers the latest insights into cancer biology Provides a broad understanding of how targeted cancer treatments work Describes many of the new immunotherapy approaches to cancer treatment, such as checkpoint inhibitors and CAR-modified T cells Helps readers feel confident discussing treatment options with colleagues and patients Provides an overview of which treatments are relevant to each of the most common solid tumours and haematological cancers, and the rationale behind them Demystifies the jargon terms such as the EMT, cancer stem cells, monoclonal antibodies, kinase inhibitors, angiogenesis inhibitors etc. Explains the resistance mechanisms to many new treatments, including issues such as the way cancer cells diversify and evolve and the complex environment in which they live

Providing the practicing and trainee hematologist with a practical and immediately applicable compendium of answers the Clinical Manual of Blood and Bone Marrow Transplantation covers the spectrum of the hematopoietic cell transplant specialty, in particular practical issues in transplant patient care, and the set up and functioning of a transplant program. * Supplies the practicing and trainee hematologist with a practical and immediately applicable compendium of answers to clinical questions * Covers the spectrum of the hematopoietic cell transplant specialty, in particular practical issues in transplant patient care, and the set up and functioning of a transplant program * Contains concise chapters written with a focus on tables, algorithms and figures to aid rapid referral * Benefits from expert contributions from an international authorship

TNM Classification of Malignant Tumours eighth edition provides the latest, internationally agreed-upon standards to describe and categorize cancer stage. * Published in affiliation with the Union for International Cancer Control (UICC) * Arranged by anatomical region, this authoritative pocket sized guide contains many important updated organ-specific classifications * There are new classifications for p16 positive oropharyngeal carcinomas, carcinomas of the thymus, neuroendocrine tumours of the pancreas, and sarcomas * To facilitate the collection of stage data for cancer surveillance in low and middle income countries there are new sections on Essential TNM and Paediatric Cancer Stage * New colour presentation

Cardiovascular Hemodynamics for the Clinician, 2nd Edition, provides a useful, succinct and understandable guide to the practical application of hemodynamics in clinical medicine for all trainees and clinicians in the field. * Concise handbook to help both practicing and prospective clinicians better understand and interpret the hemodynamic data used to make specific diagnoses and monitor ongoing therapy * Numerous pressure tracings throughout the book reinforce the text by demonstrating what will be seen in daily practice * Topics include coronary artery disease; cardiomyopathies; valvular heart disease; arrhythmias; hemodynamic support devices and pericardial disease * New chapters on TAVR, ventricular assist devices, and pulmonic valve disease, expanded coverage of pulmonary hypertension, fractional flow reserve, heart failure with preserved ejection fraction and valvular heart disease * Provides a basic overview of circulatory physiology and cardiac function followed by detailed discussion of pathophysiological changes in various disease states

Dementia is the most common type of neurodegenerative disorder. Non-Alzheimer's and Atypical Dementia concentrates on each form of dementia individually, considering symptoms, diagnosis and treatment * Focuses on non-Atypical Dementia * Multidisciplinary approach to diagnosis and management * Allows development of management and care plan strategies * Practical approach including case studies * Written by a world-renowned editorial team

This innovative new textbook covers a range of clinical situations a nurse may encounter in their professional career, providing useful insights into challenging patient - and colleague - encounters. Written by a team of educators and clinicians with considerable expertise in their respective fields, the book focuses on the application of psychology in key areas of nursing (child, adult, older people, learning disabilities, mental health) providing practical approaches and techniques that nurses can use in their daily practice with patients. It includes several features to support teaching and learning: * Clearly defined learning outcomes for each chapter * Examples throughout to illustrate the application of psychology * Case studies following a student nurse through different placements and experiences during her nurse training * Structured activities and questions for discussion to encourage reflection on practice * Annotated suggestions for further reading With nurses increasingly being held to public and professional account, the importance of understanding a clinical encounter, in particular the psychological aspects of it together with developing a skillset to respond to patients, has never been greater. This accessible and entertaining book will be indispensable reading for nurses at undergraduate and graduate level, particularly those on the pre-registration nursing diploma and Bsc (Hons) in Nursing.

Clinical Guide to Cardiology is a quick-reference resource, packed full of bullet points, diagrams, tables and algorithms for the key concepts and facts for important presentations and conditions within cardiology. It provides practical, evidence-based information on interventions, investigations, and the management of clinical cardiology. Key features include: A clear evidence-base providing key guidelines and clinical trials in each chapter Coverage of examination techniques, common conditions, imaging modalities (including ECGs, chest X-rays, MRI and CT), interventional therapies, and pharmacology A companion website at www.wiley.com/go/camm/cardiology featuring audio clips, developed for differing levels of knowledge, that explain key concepts or an area in greater detail, as well as numerous additional clinical case studies, audio scripts, and self-assessment material

The Manual of Clinical Oncology, Ninth Edition, published with the International Union Against Cancer (UICC), provides a concise, accessible and feasible reference covering state of art multidisciplinary clinical oncology in order to meet the needs of clinicians caring for cancer patients throughout the world. Edited by world-renowned practising oncologists and written by key opinion leaders, this book contains authoritative and up-to-date information on cancer detection, diagnosis and treatment alongside topics such as survivorship, special populations and palliative care. Remodelled and revised for the ninth edition to provide practical information to oncology workers, the UICC Manual of Clinical Oncology is structured in two parts. Part 1 covers general principles of cancer diagnosis and management with additional attention to special settings in oncology, including supportive care and survivorship, and Part 2 covers site-specific multidisciplinary cancer management. The edition includes up-to-date summaries of all treatment modalities (medical, surgical and radiation) for all tumour sites. It also contains the latest TNM classifications outlined in the TNM Classification of Malignant Tumours. The ninth edition includes: Practical presentation with bullet points, tables, and flow charts intended to facilitate quick reference for day-to-day clinical practice in busy oncology environments, Representation of multidisciplinary care for site specific management, Evidence-based approaches to management, including specific treatment recommendations and investigations guided by clinical practice guidelines, State of art evidence-based recommendations that take into consideration the lack of availability of certain medications or resources, as well as practice variations, in different and remote regions of the world, and Contemporary topics on cancer treatment, such as cancer informatics, evidence levels, principles of prognostication, survivorship and cancer in pregnancy. Oncologists, oncologists-in-training, nurses working with cancer patients and other health professionals responsible for treating and caring for those with cancers will find the UICC Manual of Clinical Oncology an indispensable and comprehensive resource.

Textbook of Geriatric Dentistry, Third Edition provides a comprehensive review of the aging process and its relevance to oral health and dentistry. Now in full colour, this third edition has been fully revised and updated with new material encompassing recent research and clinical developments within geriatric dentistry. Written in a clear and accessible style, this is an essential guide to geriatric dental practice for undergraduate and postgraduate dentistry students and practicing clinicians alike. Key features include: * Contributions from an international group of expert authors * Comprehensive coverage of oral healthcare issues in the older adult, from demographics and physiology through to nutrition and pharmacology * Provides both foundational knowledge and a guide to clinical management * New chapters including material on orofacial pain, quality of life and treatment planning

Sexual and Reproductive Health at a Glance provides a highly-illustrated, visual introduction to all aspects of sexual and reproductive health, from basic clinical examination skills to the management of acute Sexually Transmitted Infections (STIs) and unplanned pregnancy. Covering topics which are often difficult to access as an undergraduate or junior doctor, Sexual and Reproductive Health at a Glance focuses on the fundamental principles in delivering effective contraception and sexual health care. It features high-yield information on the essential clinical topics covered in the Community Sexual and Reproductive Health (CSRH) curriculum. Presented in the familiar, easy-to-use, at a Glance format, Sexual and Reproductive Health at a Glance: Provides a quick revision of basic anatomy, physiology and clinical skills Offers balanced coverage of both male and female GU pathology, STIs and contraception Includes material on practical gynaecological procedures performed in the out-patient setting Presents a holistic approach to issues dealt with in this specialty Takes a global perspective by addressing SRH issues in different cultures and resource-limited settings Includes a companion website at www.ataglanceseries.com/sexualhealth featuring a selection of case scenarios and interactive flashcards for self-test This brand new title will provide an invaluable resource for medical and healthcare students, junior doctors, SRH trainees and busy clinicians working in other specialties.

Neonatology at a Glance provides a concise, illustrated overview of neonatal medicine. Written by leading international experts, it provides essential information on perinatal medicine, delivery, the normal newborn infant and neonatal problems encountered in neonatal intensive care units and their management. Each topic is supported by excellent illustrations, diagrams, and, for the first time, video clips to show neonatal resuscitation and stabilizing the sick newborn, normal examination, the baby with hypoxic-ischemic encephalopathy, recognition of seizures and practical procedures. Neonatology at a Glance: Provides up to date coverage of the important conditions you will encounter Covers challenging topics including pain, ethical issues, quality improvement, evidence based medicine and palliative care Features new sections on fetal medicine, respiratory support, therapeutic hypothermia, amplified EEG and perinatal neuroimaging Integrates invaluable details about practical procedures including neonatal resuscitation and transport Supplemented by video materials and artwork which can be viewed via the companion website at www.ataglanceseries.com/neonatology Neonatology at a Glance is the perfect guide for all health professionals looking after newborn infants, including pediatric trainees, medical students, neonatal nurse practitioners and neonatal nurses, therapists and midwives. For neonatologists, pediatricians and nurse tutors it is a valuable resource to assist with teaching.

Essential Clinical Neuroanatomy is an accessible introduction to regional and functional neuroanatomy, which cuts through the jargon to help you engage with the key concepts. Beautifully presented in full color, with hundreds of annotated illustrations and images, Essential Clinical Neuroanatomy begins with an introductory section on the regional aspects of the topic, then discusses each structure in detail in relation to function. Clinical examples are provided throughout, to reinforce the concepts learned and highlight their clinical relevance. Essential Clinical Neuroanatomy: * Features a dedicated chapter on the use of imaging studies used in clinical neuroanatomy, including how to evaluate these images * Highlights topics important to clinical medicine, but often neglected in other neuroanatomy texts, such as trauma, infection and congenital considerations * All illustrations and images are oriented in the clinical view, so the correlation between drawings, photomicrographs and clinical imaging is standardized and there is a seamless transition between illustrations containing basic neuroanatomical information and the relevant clinical imaging * The functional aspects of neuroanatomical structures are color-coded (green = sensory; red = motor; purple = autonomic), so that structure to function relationships can be more easily learned and retained * Includes self-assessment and thought questions in every chapter * Supported by a companion website at wileyessential.com/neuroanatomy featuring fully downloadable images, a series of PowerPoint lectures for instructors, and USMLE-compatible MCQs Essential Clinical Neuroanatomy is the perfect resource for medical and health science students taking a course on neuroanatomy, as part of USMLE teaching and as an on-going companion during those first steps in clinical practice.

Respiratory Medicine Lecture Notes covers everything from the basics of anatomy and physiology, through to the aetiology, epidemiology, symptoms and management of a full range of respiratory diseases, providing a comprehensive yet easy-to-read overview of all the essentials of respiratory medicine. Key features of this new, full-colour edition include: Updated and expanded material on chest X-rays and radiology Self-assessment exercises for each chapter A range of clinical images and scans showing the key features of each disease Fully supported by a companion website at www.lecturenoteseries.com/respiratory featuring figures, key points, web links, and interactive self-assessment questions Ideal for learning the basics of the respiratory system, starting a placement, or as a quick-reference revision guide, Respiratory Medicine Lecture Notes is an invaluable resource for medical students, respiratory nurses and junior doctors.

Surgical Patient Care for Veterinary Technicians and Nurses is a highly practical reference covering all aspects of caring for canine and feline surgical patients. Covers all tasks associated with small animal surgical patient care, from the initial exam and beyond discharge Offers clear descriptions of common surgical assisting procedures and their etiology Presents 285 full-color clinical photographs to demonstrate common surgical instruments and assisting procedures and patient care Includes chapters on the history and physical examination, pre-operative planning, asepsis, surgical assisting, procedures, wound management, postoperative care, and aftercare Includes access to a companion website with review questions and answers and the figures from the book in PowerPoint