"Tumor Immunology and Cancer Vaccines" addresses the state of the art knowledge of tumor immunology relevant to cancer vaccine and the different aspects of cancer vaccine development, covering the field from its basic science logic to clinical trials. The four sections of the book, Basic Tumor Immunology; Cancer Vaccine Development; Vaccine-Enhancing Strategies; and Clinical Trials Design, provide a general overview of the field, historic background, and the field's promises and problems.
Indice testuale
Basic Tumor Immunology.- Antigen Processing and Presentation.- Antigen Recognition and T-Cell Biology.- Mechanisms of Tumor Evasion.- Tumor Antigens and Tumor Antigen Discovery.- Cancer Vaccine Development.- Peptide Vaccines Against Cancer.- DNA Vaccination in Immunotherapy of Cancer.- Antibody Inducing Polyvalent Cancer Vaccines.- Dendritic Cell-Based Vaccines for Cancer Therapy.- Undefined-Antigen Vaccines.- Cancer Vaccines in Combination with Multimodality Therapy.- Vaccine-Enhancing Strategies.- Cytokine Therapy for Cancer: Antigen Presentation.- Tinkering with Nature: The Tale of Optimizing Peptide Based Cancer Vaccines.- Tumor Immunology and Cancer Vaccines.- Clinical Trials Design.- Clinical Trial Designs for Therapeutic Cancer Vaccines.- Clinical Trial Design and Regulatory Issues for Therapeutic Cancer Vaccines.- Immune Monitoring.
