International radiation oncologists, surgeons, and scientists comprehensively review the techniques, indications, and results of using intraoperative electrons (IOERT) and high-dose rate brachytherapy (HDR-IORT). State-of-the-art topics range from methods and techniques of treatment and issues of normal tissue/organ tolerance to IORT, to techniques and results by disease-site, as well as future possibilities. The disease-site chapters cover every body part for which the potential merit of IORT has been demonstrated, with disease-specific treatment factors presented by a radiation oncologist and a surgeon. The diseases range from GI cancers to CNS and breast malignancies. International in authorship and comprehensive in scope, Intraoperative Irradiation: Techniques and Results offers a cutting-edge resource and reference for surgeons, radiation oncologists, physicists, anesthesiologists, medical oncologists, and all others involved in providing IORT and HDR-IORT procedures and cancer care today.
Indice testuale
Section I. Introduction: General Rationale and Historical Perspective of Radiobiology. Radiobiology of High Dose Per Fraction Irradiation. Section II: Methods and Techniques of Treatment: Radiation Factors and the Intraoperative Electron Irradiation Technique (IOERT). Physics of IOERT. Radiation Factors and the Intraoperative High Dose Rate (IOHDR) Brachytherapy Technique. Physics of IOHDR Brachytherapy. Comparisons and Advantages of IOERT and IOHDR. Section III. Normal Tissue Tolerances: NCI Single Fraction Experience. CSU Animal Experience. Peripheral Nerve Tolerance. Section IV. Results of IOERT and External Beam Irradiation (EBRT) by Disease Sites: Gastric. Pancreas. Billiary Tract. Colorectal. Liver. Sarcomas. Gynecological. Genitourinary. Lung. Head and Neck. Pediatric. CNS. Conclusions and Future Possibilities. Index.
