Oncologia

Covering tumors of the nose, sinuses, and nasopharynx for the first time in a single volume, this book is essential for all specialists. It incorporates the newest techniques for evaluation and treatment, including endoscopic approaches to the skull base, and offers a wealth of evidence-based data and analysis. For all members of the multidisciplinary health care teams who manage these complex cases, this book makes a major contribution to the field. Special Features: * Written by three international authorities who have published and lectured widely and conducted landmark studies in this area* Covers the full range of benign and malignant nose and sinus tumors, as well as the specific nasopharyngeal tumors that are more common to certain geographic regions (Far East) and ethnic groups (Chinese origin)* Content is based on one of the largest single institutional studies ever undertaken, plus an extensive review of the international literature * Encompasses every aspect of the field, from etiology, clinical features, histology, imaging studies, and diagnosis to natural history, treatment options, outcomes, and management of residual or recurrent disease* Includes up-to-date contributions from experts on chemoradiation and head and neck imaging With the goal of centralizing data and long-term follow-up, this comprehensive guide is invaluable for all otolaryngologists, head and neck surgeons, oncologists, neurosurgeons, and maxillofacial and plastic surgeons who treat patients with challenging sinonasal, skull base, and nasopharyngeal neoplasms. Thieme eOtolaryngology is the premier online resource for otolaryngology-head and neck surgery. For a free trial, go to: thieme.com/eototrial

I tumori cerebrali infantili sono forme eterogenee, a prognosi incerta e ad altissima complessità assistenziale

In Italia sono circa due milioni e ottocentomila le persone che hanno ricevuto una diagnosi di cancro

The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip you to understand and apply the complexities of ongoing research in everyday clinical application.

Il termine "palliativo" deriva da pallium, che nella Roma antica designava il telo di lana che si poggiava su una spalla e si drappeggiava intorno al corpo, per proteggerlo. Nella medicina moderna questo termine ha purtroppo assunto un significato vagamente negativo, di rimedio sostitutivo, inadatto a risolvere del tutto un problema di salute. Il marito di una paziente ci ha detto: "Non vogliamo cure palliative. Vogliamo medicina, non carità!". Si dimentica invece che con esso si designa tutto un complesso di cure, che sarebbe più appropriato definire "di supporto". Le cure palliative non sono rimedi inefficaci, al contrario. Studi clinici testimoniano la loro validità anche in termini di sopravvivenza e di miglioramento della qualità di vita. Nonostante molti medici siano convinti che le cure palliative aiutino molto, essi le prescrivono generalmente troppo tardi. Le cure palliative si prefiggono di mantenere la qualità della vita e il diritto alla vita del paziente sino alla morte, di alleviarne le sofferenze, nel rispetto dei suoi desideri e delle necessità fisiche, psicologiche, morali, sociali, esistenziali e culturali.

Sia che si pratichi l'allopatia, sia che si pratichi l'omeopatia, la qualità di vita dei pazienti oncologici deve essere oggetto di attenzione da parte del medico. A questo proposito, i trattamenti di supporto devono essere somministrati con la stessa attenzione riservata ai trattamenti antitumorali specifici, per prevenirne al meglio gli effetti collaterali. In questo contesto l'omeopatia, che non può in alcun caso sostituirsi ai trattamenti convenzionali, si integra nell'ambito di una presa in carico multidisciplinare. La terapia omeopatica ci permette di fornire una risposta a molti problemi indotti dalla malattia oncologica o dai suoi trattamenti. In questo volume, gli autori forniscono un prezioso e aggiornato strumento di riferimento per poter affrontare il follow-up dei pazienti sottoposti a trattamento oncologico attraverso schede di facile consultazione, con una presentazione farmacologica di ciascun farmaco antitumorale, seguita dalla descrizione dei principali medicinali omeopatici indicati per gli effetti collaterali incontrati abitualmente e l'indicazione del trattamento da instaurare al più presto, se possibile prima di iniziare la chemioterapia.

This is a concise yet thorough overview of the medications and approaches used in cancer care - backed by the authority of Harrison's. Harrison's Manual of Oncology is a carry-anywhere guide to the care of patients with cancer. Enhanced by the latest published results, this valuable clinical companion features numerous tables and succinct, outline-style text that puts important information at your fingertips. You will find content that goes beyond the treatment of primary or metastatic disease to encompass the treatment of all therapeutic complications. The opening sections of Harrison's Manual of Oncology are devoted to the classes of agents used to treat cancer and reviews their pharmacology and mechanisms of action. This section is followed by a detailed discussion of the diagnosis, staging, and treatment of all major types of cancer. There is a strong focus on symptom management and complications of treatment, including pain, nausea and vomiting, anemia, febrile neutropenia, metabolic emergencies, thrombosis, psychological issues, and end-of-life care.

Ovarian Cancer: Advances in Diagnosis and Management presents unique international perspectives on this devastating disease. While ovarian cancer has mainly been considered a disease of the Western hemisphere, this book moves beyond our conventional understanding and embraces knowledge from around the world. The focus is on recent advances in diagnosis, including genetic screening, and improvements and expanded choices in management, such as the optimization of chemotherapeutic agents, gene therapy, and the latest laparoscopic and robotic surgical techniques. Further chapters address psychosocial and quality-of-life issues. This book is an excellent resource on the international state-of-the-art in the diagnosis and management of ovarian cancer and is aimed at oncologists, gynecologists, and fellows.

The Third Edition of Knowles Neoplastic Hematopathology has been thoroughly updated by the world's experts to cover all aspects of neoplastic hematopathology, a field that covers disorders of the bone marrow, spleen, and lymphatic system. Now in full-color, this completely revised and expanded edition integrates the basic science, modern diagnostic techniques, and clinical aspects of malignant diseases affecting these organs. It is the most comprehensive, encyclopedic textbook concerning neoplastic hematopathology available on the market today. Features: more than 2,000 four-color illustrations; in-depth coverage all the three major organ systems; new chapters on lymphoplasmacytic lymphoma, hematolymphoid lesions of the lung and pleura, plasmacytoid dendritic cell neoplasms, and myelodysplastic/ myeloproliferative neoplasms and related diseases; emphasizes the expanding role of molecular diagnostics; and interactive companion website with image bank.

2014 BMA Medical Book Awards Highly Commended in Oncology category! Adhere to best practices and achieve best outcomes with Clinical Interventional Oncology! Loosely structured around the concept of a "tumor board," this groundbreaking oncology reference delivers a comprehensive arsenal of information on the techniques and treatment protocols surrounding chemoembolizations, tumor ablations, minimally invasive tumor biopsies, and other interventional oncologic procedures. Ideal for all members of the cancer care team, it provides the "how to" guidance you need on the clinical, evidence-based application of each interventional procedure.

Imaging of Soft Tissue Tumors, Third Edition Imaging technology plays an essential role in the diagnosis of soft tissue tumors as well as in surgical planning. Not only can imaging studies such as CT and MRI determine the relationship between a tumor and adjacent vessels and nerves, but, because some soft tissue tumors possess specific radiologic presentations, imaging can help pinpoint the tumor type. Based on cases seen at the Armed Forces Institute of Pathology and the Mayo Clinic, this comprehensive reference offers detailed visually supported information on the radiologic evaluation of soft tissue tumors and tumor-like lesions. Inside, readers will explore the full spectrum of soft tissue pathologies, with over 1400 images that highlight both common and atypical presentations. The book's expert authors offer valuable advice on selecting the most appropriate imaging modality for each tumor type. Features: broad scope presents the results of a retrospective analysis of over 31,000 cases of soft tissue tumors and tumor-like masses; comprehensive coverage addresses lipomatous, vascular and lymphatic, fibrous and fibrohistiocytic, muscle, neurogenic, synovial, extraskeletal osseous and cartilaginous tumors; detailed information on all imaging modalities-including CT, MRI, radiography, angiography, scintigraphy, ultrasound, and positron emission tomography-are covered, with facts on the strengths and limitations of each to help readers select the most appropriate method; high-quality images aid in the visual diagnosis of typical and atypical tumor presentations; world Health Organization nomenclature (in accordance with the 2013 updated classification) is included throughout the text, emphasizing applicable changes in each chapter; and a new chapter examines the imaging of superficial masses.

Since the last edition of this book, major advances have been made in our understanding of key pathways that control tumor progression. This has led to the development of new anticancer agents that have the ability to block the activity of proteins involved in neoplastic cell development and proliferation. Targeted Therapies in Oncology, Second Edition provides a concise timely panorama of existing targeted therapies and progress into future anticancer treatments. These therapies notably include: Targeted agents of immune checkpoints Signal-transduction inhibitors Antiangiogenic agents Vascular-disrupting agents Apoptosis modulators Stem cell inhibitors Tumor profiling for drug development The book emphasizes the biology behind this new class of drugs as well as the clinical achievements obtained. The contributors to this volume stand at the cutting edge of cancer research and treatment around the world.

The third edition of Intensity Modulated Radiation Therapy was written to enhance the reader's understanding of the cutting-edge technology of Intensity Modulated Radiation Therapy. It is designed to both update old readers and inform new readers about the complexities and details of clinical management. This completely updated edition provides a step-by-step, practical approach to the use of IMRT in the evaluation and treatment of cancer patients. Because of IMRT's ability to employ individually controlled beamlets, it is an extremely promising technique, especially when paired with CT, PET, and/or MRI. With these improved procedures, doctors and clinicians will be able to take high resolution images of tumors while minimizing dosages to surrounding tissue. In order to focus on the most up to date IMRT techniques, the introductory chapters have been condensed to provide a brief overview of IMRT physics, mechanics and quality assurance, and also CT and MR imaging. To help assist in clinical decision-making it provides the reader with more than 700 full-color illustrations, IMRT tables and clear, straightforward descriptions that address a range of tumor types and sites including head and neck, urinary, and gynecologic cancers. Features: anatomy and anatomical imaging supports your understanding of IMRT and its advantages; over 700 high-quality, full-color illustrations to assist in clinical decision-making and over 90 new patient treatment graphics, updated in full-color; new chapters on anatomy and normal tissue complications, CNS, pancreas, rectum, and anal cavity; a new chapter on molecular imaging, focusing on new PET tracers for image-guided therapy; updated with new clinical data; review of current IMRT literature summarized in tables; includes clinical indications, image interpretation, target delineation, and plan optimization to help refine techniques, pinpoint treatment areas, and improve outcomes; new Chapters on pancreatic, rectal, and anal canal cancers included, with a focus on IMRT's treatment of these diseases; and chapters on breast and gynecological cancer are completely rewritten to include pertinent information on technique and application.

Lung cancer is the most common cause of cancer-related death in the world. Recently, better understanding of the biology of lung cancer has led to the development of newer targeted therapies for specific subpopulations of lung cancer patients. While this has led to multiple exciting advances that promise to improve outcomes in the future, there has also been a significant increase in the complexity of care of the lung cancer patient. Part of the Oxford American Oncology Library, this concise handbook identifies best-practice guidelines, as well as differences of opinion in the field. It presents the most current procedures for the diagnosis and management of lung cancer in a succinct and easy-to-read manner. Chapters focus on topics such as the biology, pathology, and staging of lung cancer, special populations, and supportive care. Lung Cancer is a must-have tool for busy oncologists.

ABC of Cancer Care is a practical primary care guide to help health professionals better inform their patients, manage and recognize the common complications of cancers and their treatment, and understand the rationale and implications of decisions made in secondary and tertiary care. It provides coverage of the diagnosis, management, treatment and on-going surveillance of common cancers within the multidisciplinary context of primary care. Individual chapters assess the different treatment options, including surgery, radiotherapy and chemotherapy, and examine their possible side effects. The contribution of clinical trials and new advances in cancer treatment including biological and targeted therapies, robotic surgery and advanced radiotherapy techniques are all described. Other aspects of cancer care, from nursing support and nutrition to psychological care and survivorship, are also covered. Edited by a specialist and general practitioner team, with multidisciplinary contributors, ABC of Cancer Care is ideal for general practitioners, practice nurses, cancer care nurses, medical students, and all healthcare professionals treating and supporting cancer patients.