Neurologia

In 2007, between 40,000 and 50,000 people in the United States will be diagnosed with primary brain tumors, the majority of whom will be adults. Three times this number will develop metastatic brain tumors from cancer originating elsewhere in the body.This issue of "Neurologic Clinics" contains the following articles: Epidemiology of Brain Tumors (Wrensch, Claus); Molecular Pathogenesis of Brain Tumors and the Role of Stem Cells (Ligon, Kesari); Advances in Neuroimaging of Brain Tumors (Henson); Medical Management of Brain Tumor Patients (Schiff, Wen); Advances in Neurosurgery for Brain Tumors (Shaffrey); Advances in Radiation Therapy for Brain Tumors (Mehta); Novel Therapies for Brain Tumors (Wen, Schiff); Anaplastic Astrocytomas and Glioblastomas (Reardon); Anaplastic Oligodendrogliomas and Anaplastic Oligoastrocytomas (Van Den Bent); Low-Grade Gliomas (Lang, Gilbert); Brain Metastases (Deangelis); Benign Brain Tumors (Link); Primary CNS Lymphoma (Abrey); and Genetic Causes of Brain Tumors (Plotkin).

Parkinson's disease (PD) is the second most common neurodegenerative disease in the world. Still the only major text on the subject, the completely revised and updated second edition of "Parkinson's Disease: Diagnosis and Clinical Management" comes at a time when specialists have made important advances in our understanding of the etiology, pathogenesis, investigation, and management of Parkinson's disease.The book includes 23 completely new chapters, and has updated information on: Genetics; Pathology; Biomarkers; Pathogenesis; Impulse control disorders in Parkinson's disease; Updated outcome measures; and, complementary and alternative medicine for the treatment of Parkinson's disease.Together the chapters form a comprehensive review of the many issues facing PD physicians today. Lucid and easily readable from beginning to end, each chapter may also stand on its own as a scholarly review of the individual subject. Each one is concisely written and heavily referenced for this purpose.The second edition of "Parkinson's Disease: Diagnosis and Clinical Management" provides a state-of-the-art review of where we've been, where we are now, and where we are going in treating this disease.

The new edition of this indispensable reference features the clinical experience of seasoned experts coupled with fresh perspectives from five new authors, providing you with well-rounded, up-to-date coverage on treating all aspects of nerve injuries. Abundant case studies, descriptive examples of major peripheral nerve injuries and other lesions, and outcome analyses help you implement the most appropriate treatment plan for each individual patient. Plus, the all new full-color design throughout offers exceptional visual guidance on surgical techniques.

This atlas instills a solid knowledge of anatomy by correlating thin-section brain anatomy with corresponding clinical magnetic resonance images in axial, coronal, and sagittal planes. The authors correlate advanced neuromelanin imaging, susceptibility-weighted imaging, and diffusion tensor tractography with clinical 3 and 4 T MRI. Each brain stem region is then analyzed with 9.4 T MRI to show the anatomy of the medulla, pons, midbrain, and portions of the diencephalonin with an in-plane resolution comparable to myelin- and Nissl-stained light microscopy. The book's carefully organized diagrams and images teach with a minimum of text.

The field of epilepsy and behavior has grown considerably in the past number of years, reflecting advances in the laboratory and clinic. "Behavioral Aspects of Epilepsy: Principles and Practice" is the definitive text on epilepsy behavioral issues, from basic science to clinical applications, for all neurologists, psychosocial specialists, and researchers in the fields of epilepsy, neuroscience, and psychology/psychiatry.Behavioral aspects of epilepsy include a patient's experiences during seizures, his or her reaction during and between seizures, the frequency of episodes and what can be determined from the number of seizures. With contributions by dozens of leading international experts, this is the only book to cover all aspects of this critical emerging. Adult and pediatric patients, animal models, and epilepsy surgery and its effects are all covered in detail."Behavioral Aspects of Epilepsy" is the only source for up-to-date information on a topic that has significant and growing interest in the medical community. This comprehensive, authoritative text has a "bench to bedside" approach that covers: the mechanisms underlying epilepsy and behavior; neurophysiologic function; neuropsychiatric and behavioral disorders in patients with epilepsy; the effects of treatments and surgery on behavior; pediatric and adolescent epilepsy; disorders associated with epilepsy that impact behavior; and much more.

Computational neuroscience is a relatively new but rapidly expanding area of research which is becoming increasingly influential in shaping the way scientists think about the brain. Computational approaches have been applied at all levels of analysis, from detailed models of single-channel function, transmembrane currents, single-cell electrical activity, and neural signaling to broad theories of sensory perception, memory, and cognition. This book provides a snapshot of this exciting new field by bringing together chapters on a diversity of topics from some of its most important contributors.This includes chapters on neural coding in single cells, in small networks, and across the entire cerebral cortex, visual processing from the retina to object recognition, neural processing of auditory, vestibular, and electromagnetic stimuli, pattern generation, voluntary movement and posture, motor learning, decision-making and cognition, and algorithms for pattern recognition. Each chapter provides a bridge between a body of data on neural function and a mathematical approach used to interpret and explain that data.These contributions demonstrate how computational approaches have become an essential tool which is integral in many aspects of brain science, from the interpretation of data to the design of new experiments, and to the growth of our understanding of neural function. This book includes contributions by some of the most influential people in the field of computational neuroscience. It demonstrates how computational approaches are being used today to interpret experimental data. It covers a wide range of topics from single neurons, to neural systems, to abstract models of learning.