Medicina

Written by experts on the forefront of investigations of brain function, vision, and perception, the material presented is of an unparalleled scientific quality, and shows that analyses of enormous breadth and sophistication are required to probe the structure and function of brain regions. The articles are highly persuasive in showing what can be achieved by carrying out careful and imaginative experiments. "The Cat Primary Visual Cortex" should emerge as essential reading for all those interested in cerebral cortical processing of visual signals or researching or working in any field of vision. Key features include: comprehensive account of cat primary visual cortex; generous use of illustrations including color; coverage of research from structure to connections to functions; chapters by leaders in the field; and, topics presented on multiple, compatible levels.

Recent years have seen major advances in the understanding of motor and non-motor operations of the cerebellum, including its role in cognition, and important discoveries in the genetics of the cerebellar ataxias. This is a comprehensive text on the cerebellum and its disorders. It ranges from embryology and basic neuroanatomy to a thorough survey of the sporadic and hereditary disorders of the cerebellum. Models of cerebellar function and clinical-pathophysiological correlations are thoroughly covered, and there is an extensive and authoritative review of recent advances in the genetics of cerebellar diseases. The chapters are written by the leading international authorities on the cerebellum, including many of those who made fundamental discoveries in the field. The first comprehensive text on the cerebellum to be published for many years, this book will be essential reading for a wide range of basic and clinical neuroscientists, neurologists and others studying or treating cerebellar disorders.

The Manual of Arthroscopic Surgery provides the most up to date state of the art for all those dealing with arthroscopic diagnosis and treatment. A standardised structure of the individual chapters facilitates the retrieval of information: Diagnosis, therapeutic management including decision-making for conservative and operative treatment, arthroscopic results and surgical techniques. The latter are described in a practical how-to-do step-by-step manner. 2,000 brilliant figures illustrate each operative step. The comprehensive manual includes rare conditions as well and provides detailed information on tricks and pitfalls. In its entirety it reflects the most up to date high-tech standard of arthroscopy.

Since the publication of the first edition of Introduction to Toxicology , toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing. This third edition caters for this need in a clear and easy-to-read style, featuring: * Up-to-the-minute information * Relevant toxicological examples that reinforce principles * End-of-chapter essay questions * New and redrawn illustrations * Glossary of terms * Extensively revised bibliography The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.

The revised and updated new edition of this text clearly describes and illustrates the key steps to the surgical management of female genitourinary disorders. Over 505 illustrations - with more than 355 full-color intraoperative photographs - offer step-by-step guidance on the surgical treatment of urinary incontinence, vaginal prolapse, vesicovaginal fistulae, and other common procedures. Plus, a new CD-ROM bound with the book allows readers to observe eight crucial surgical techniques.

This atlas presents the key concepts of genitourinary oncology in a highly accessible, visual format. It covers all of the major primary sites encompassed by this vast discipline, including the prostate, bladder, kidneys, and testes. Readers will find classic diagnostic images from the personal collections of expert contributors, simple diagrams of molecular biology concepts, and algorithmic presentations of treatment strategies, results, and complications.

Leading researchers synthesize scattered experimental data to help develop an intimate understanding of how cytokines and chemokines are involved in the pathogenesis of autoimmune diseases. The many chapters offer critical reviews the basic mechanisms controlling cytokine induction and regulation, as well as the resulting production of proinflammatory and anti-inflammatory cytokines, the former of which induces organ-specific autoimmune diseases. From the vantage of these insights, they address the role of cytokines in a wide variety of autoimmune diseases, uvetis, encephalomyelitis, multiple sclerosis, human type 1 diabetes, rheumatoid arthritis, SLE, and myasthenia gravis. Authoritative and state-of-the-art, Cytokines and Autoimmune Disease highlights the enormous therapeutic potential of cytokine modulation in the treatment of autoimmune disease.

In recent years advances in laparoscopic technologies have led to renewed interest in the vaginal approach to hysterectomy, which has many proven benefits for patients. This volume, dedicated to explaining and promoting the vaginal route of hysterectomy, is written and edited by an international team of experts and provides a much-needed source of up-to-date information and instruction. Importantly, the authors caution that laparoscopic technology can provide a valuable source of assistance for the gynaecological surgeon in certain circumstances, though only in a percentage of cases. This book, beautifully illustrated with line drawings and full-colour photographs, contains step-by-step surgical techniques, enabling the surgeon to gain confidence and experience so that gradually more challenging operations can be managed successfully via the vaginal route. Acknowledged authorities from around the world take the reader through the indications and contra-indications for the vaginal approach, explain crucial preoperative assessment procedures, and offer an evidence-based elucidation of the 'why', 'when' and 'how' of vaginal hysterectomy. Specific topics considered here include: the nulliparous patient, uterine fiboids, debulking, the use of gonadtrophin-releasing hormone agonists, oophorectomy and prophylactic oophorectomy, adnexectomy for adnexal pathology, genital prolapse, the place of sacrospinous colpopexy, urethral sphincter incompetence, hormone replacement therapy, and the psychological and sexual outcomes of hysterectomy. In addition, the authors set forth the arguments for and against vaginal hysterectomy, abdominal hysterectomy, laparoscopic assistance, and transcervical resection of the endometrium. Combined with a full review of the potential complications, morbidity and mortality associated with the vaginal approach, this book provides the reader with a well-balanced, thorough and considered appraisal of vaginal hysterectomy. As the incidence of hysterectomy worldwide continues to rise, Vaginal Hysterectomy will be an indespensable reference for practising gynaecologists, surgeons, consultants and postgraduates.

For courses in Anatomy and Physiology for EMS. This first and only EMS specific text has been developed to meet the needs of an EMS program and the interests of EMS students, covering appropriate anatomy and physiology as well as specific clinical applications. It will enable students to develop their problem solving skills, build a foundation of basic concepts and essential knowledge, and master terminology and principles important to an understanding of the human body.

"Febrile Seizures" is written by the most active researchers and clinicians in epilepsy research today. This book presents the latest developments in this field as well as the current state of knowledge in the following fields: new imaging tools and emerging data, visualizing effects of febrile seizures on the brain, new genetic methodologies, and the use of animal models to permit scientific analysis of the electrophysiology and molecular biology of the seizure. Its key feature is that it is the first book on febrile seizures in over 20 years! It covers the broad spectrum of approaches, from genetic and epidemiological to bench research using animal models and in vitro single-cell patch-clamp methods. It contains a comprehensive update of the topic, written by world leaders in the field. It features novel and newly discovered information based on up-to-the-minute methods, and uses an engaging style, that is accessible to the clinician, researcher, and the educated parent.

This work provides the practicing ophthalmologist with a comprehensive volume that presents both immunologic fundamentals as they relate to uveitis and the practical approach to the treatment of these diseases. Dr. Foster is the leader in the aggressive medical management of ocular inflammatory disaseses, and the book reflects twenty-five years of experience in the world's busiest uveitis clinic. Featuring contributions from 60 international specialists, the book provides encyclopedic coverage of basic science, diagnosis, and clinical management, as well as thorough discussion of ocular inflammatory diseases in all regions of the world.

This title is perfect as a study tool or a quick reference! This new resource presents realistic case studies in a unique question-and-answer format to help assess readers' knowledge in this sub speciality, pass certification exams, and succeed in practice. It's practical organization and outstanding illustrations make it easy to hone clinical skills.