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Endocrinologia e metabolismo

Neuropatia diabetica dolorosa

V. Spallone

editore: Elsevier

pagine: 104

Questo manuale affronta il problema della neuropatia diabetica dolorosa, con l'intento di offrire una sintesi chiara e una prospettiva clinica di questa complessa realtà. Sono descritti i quadri clinici delle neuropatie diabetiche associate a dolore neuropatico e della NDD, con indicazioni epidemiologiche sulle dimensioni del problema e sulle sue implicazioni, sull'approccio diagnostico alla PND e al dolore neuropatico della NDD, sul trattamento patogenetico della PND, sui farmaci sintomatici e sulla strategia di trattamento secondo le evidenze e le linee guida disponibili.
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Il paziente con diabete ed epatopatia cronica

Alessandro Grasso

editore: SEEd

pagine: 128

La contemporanea presenza in uno stesso paziente di diabete mellito ed epatopatie croniche, benché piuttosto frequente, non ha avuto nella letteratura scientifica la stessa attenzione rispetto ad altre associazioni. Il libro analizza il ruolo patogenetico dell'insulino-resistenza, i rapporti tra obesità, sindrome metabolica ed epatopatie e l'associazione tra infezione da virus dell'epatite e diabete, fornendo ampia documentazione sull'importanza che deve essere posta da parte del medico nel ricercare precocemente i possibili segni di una complicanza metabolica nel paziente epatopatico o viceversa un possibile danno epatico nel paziente diabetico. L'approccio pratico rende il libro particolarmente utile a chi deve affrontare le quotidiane problematiche di inquadramento di pazienti polipatologici.
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Il diabete nell'anziano e il rischio di disabilità

Claudio Marengo, Marco Comoglio

editore: SEEd

pagine: 104

Nel paziente anziano il diabete è in grado di accelerare altre condizioni patologiche concomitanti rendendo più complessa l'assistenza. Il medico che si trova di fronte a un paziente diabetico anziano dovrà pertanto prendere in considerazione anche le comuni sindromi geriatriche più frequenti nel soggetto diabetico e che possono avere un effetto molto negativo sulla qualità di vita e sull'autonomia del malato. Il presente testo desidera quindi fornire alcune indicazioni sulle complicanze geriatriche correlate al diabete, soprattutto al fine di sensibilizzare il curante verso la loro possibile presenza, in modo che tali patologie interferiscano il meno possibile con la cura più adeguata.
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The Bethesda System for Reporting Thyroid Cytopathology

Definitions, Criteria and Explanatory Notes

Edmund S. Cibas, Syed Z. Ali

editore: Springer-Verlag New York Inc.

pagine: 188

This atlas is the offspring of the "The National Cancer Institute (NCI) Thyroid Fine Needle Aspiration (FNA) State of the Science Conference," hosted by the NCI and organized by Dr. Andrea Abati. Preparations for the conference began 18 months earlier with the designation of a steering committee and the establishment of a dedicated, p- manent web site. The meeting took place on October 22 and 23, 2007 in Bethesda, Maryland and was co-moderated by Susan J. Mandel and Edmund S. Cibas. The discussions and conclusions regarding terminology and morphologic criteria 1, 2 from the meeting were summarized in publications by Baloch et al. and form the framework for this atlas. The atlas is organized by the general categories of "Nondiagnostic," "Benign," "Follicular Neoplasm/Suspicious for a Follicular Neoplasm", "Suspicious for Malignancy," and "Malignant," and it includes the defi- tions and morphologic criteria of these categories as set forth by Baloch et al. The majority of the conference participants also agreed on a category of "undetermined significance," which is incorporated in this atlas (Chap. 4). It is critical that the cytopathologist communicate thyroid FNA interpretations to the referring physician in terms that are succinct, unambiguous, and helpful clinically. We recognize that the terminology used here is a flexible framework that can be modified by individual laboratories to meet the needs of their providers and the patients they serve.
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Clinical Obesity in Adults and Children

Ian D. Caterson, Peter G. Kopelman
e altri

editore: Wiley-Blackwell (an imprint of John Wiley & Sons Ltd)

pagine: 512

Obesity is a major problem facing doctors in the 21st century. This third edition of a highly-respected textbook combines the latest in clinical research with a practical approach to guide the successful evaluation, management and treatment of the obese patient including the large number of complications and other conditions that can arise as a consequence of it. Written by experts from around the globe, this book is a truly international work recognizing that the approach for the treatment and management of obesity may vary between differing ethnicities and in different countries. The book addresses obesity and its social and cultural aspects, biology, associated diseases, life stages (pediatric and adult), management, and environmental policy approaches in six sections. As well as covering the latest approaches to treatment of obesity, Clinical Obesity in Adults and Children considers the effects of the environment, of gender and of culture on this problem. This is an invaluable resource for all health care professionals, research scientists and public health practitioners involved in the prevention and care of patients who are at risk of obesity or are already obese.
180,00 153,00

The Johns Hopkins Textbook of Dyslipidemia

Peter O. Kwiterovich

editore: Lippincott Williams and Wilkins

pagine: 320

The first comprehensive text on dyslipidemia from a major academic institution, this book covers all aspects of dyslipidemia as it relates to human disease, including coronary artery disease, cerebrovascular disease, peripheral vascular disease, and pancreatitis. The material is presented in a clinician-friendly format and includes references for additional reading. Reflecting current guidelines from the National Cholesterol Education Program, the book explains why, when, and how to treat dyslipidemia. Coverage includes dietary treatment, drug treatment, and recommendations for special populations such as patients with coronary heart disease, patients at high risk for coronary heart disease, patients with diabetes, women, older adults, young adults, and racial and ethnic groups.
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Obesity and Cardiovascular Disease

Gianluca Iacobellis

editore: Oxford University Press

pagine: 288

The number of individuals who are obese or overweight has dramatically increased over recent years and is now becoming epidemic.These individuals are more likely to suffer cardiovascular diseases and therefore physicians, specialists and trainees increasingly need to deal with these issues on the ward and in clinic. As a result, the need for appropriate knowledge of up-to-date clinical management of obesity and its associated cardiovascular problems is essential for any practising physician. Obesity and Cardiovascular Disease is a readily assimilated pocket guide to obesity and cardiovascular disease. It is intended to be used 'on-the-go' and is compact enough to be on hand whilst in consultation with patients. It provides a clear and succinct overview of contemporary clinical management of cardiovascular risk stratification, and fully covers the diagnosis and treatment of cardiovascular in obese patients and individuals with increased visceral adiposity, translating up-to-date clinical research findings into clinical practice. Particular emphasis is placed on recent updates in practical care in obesity and cardiovascular disease, such as new diagnostic techniques and novel pharmacological and surgical approaches, as well as cardiac visceral fat, ethnic differences in adiposity-related cardiovascular risk, and metabolically healthy, but obese subjects. Topics are presented in an easily accessible format with numerous illustrations, photographs, tables, diagnostic and therapeutic algorithms while highlight boxes summarise the main concepts discussed in each chapter.
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Atlas of Endocrine Surgical Techniques

Electron Kebebew, Orlo H. Clark
e altri

editore: Saunders

pagine: 260

"Atlas of Endocrine Surgical Techniques", a title in the new Surgical Techniques Atlas series edited by Drs. Townsend and Evers, presents state-of-the-art updates on the full range of endocrine surgical techniques performed today. Drs. Duh, Clark, and Kebebew, along with esteemed international contributors, offer you expert advice on a variety of endocrine surgical techniques, including laparoscopic and endoscopic procedures to help you expand your repertoire and hone your clinical skills. Full-color illustrations and photographs enhance visual guidance and Expert Consult functionality gives you easy access to the full text online.
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Novel Therapies in Hepatitis C Virus, an Issue of Clinics in Liver Disease

Paul J. Pockros

editore: Saunders

The Guest Editor presents state-of-the-art articles devoted to therapies for treatment of HCV. The novel therapies addressed in this issue include interferons, viral kinetics and anti-viral resistance, anti-fibrotics, immunotherapeutics, hepatoprotectants and caspace inhibitors, and cyclosporine analogues, to name a few.
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Endocrine Surgery

A Companion to Specialist Surgical Practice

Tom W. J. Lennard

editore: Saunders (W.B.) Co Ltd

pagine: 244

Ever since the publication of the first edition in 1997, the "Companion to Specialist Surgical Practice" series has met the needs of surgeons in higher training and practising consultants by providing contemporary, evidence-based information on the sub-specialist areas relevant to their general surgical practice. All eight volumes are thoroughly edited and supported by evidence-based references to support key recommendations. This new Fourth Edition brings together the relevant state-of-the-art specialist information that the editors and authors consider important for the practising sub-specialist general surgeon. Purchase of a print book also includes a downloadable version of the eBook.
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Pancreatology

Juan Iovanna, Uktam Ismailov

editore: Springer-Verlag Berlin and Heidelberg GmbH & Co. K

pagine: 102

Basic research discusses the implication of pancreatic stress protein in acute pancreatitis and pancreatic cancer and their possible role as therapeutic targets. Also, very original results show the unexpected role of lipids as mediators during acute pancreatitis. Gene screening strategies allow the detection of the genes responsible for gemcitabine resistance of pancreatic cancer cells. They lead to the selection of several target genes, in order to suppress the resistance of cells to gemcitabine treatment. The mechanism by which tetrahydrocannabinol is anti-tumoral in pancreatic cancer cells is presented and the use of THC as a promising new therapeutic agent is discussed. Genetic data are shown concerning hundreds of families with hereditary chronic pancreatitis and their possible role in the pathogenesis of the disease. Another very original study addresses the prevention and treatment of pancreatic diseases with diet. In clinical research, convincing data about the use of endoscopic sphicterotomy in the management of acute bilary pancreatitis is presented, based on the experience of a Center highly specialized in pancreatic diseases.
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Clinical Endocrinology and Diabetes Mellitus

Y. Sachdev

editore: McGraw-Hill Medical

pagine: 1085

This is the first comprehensive textbook on endocrinology and diabetes mellitus! This book links the practice of clinical medicine and science of endocrinology by presenting a balanced and evidence-based account of various endocrinology problems. It provides insights into various types of common and not so common complexities of disease and its management. Diabetes is potentially preventable with lifestyle modifications and medication; similarly, numerous nutritional deficiency diseases are also preventable. The book looks closely at new developments about the endocrines and their dysfunctional states and explains how clinical intervention with appropriate tests and early diagnosis can prevent or delay the onset of disease. The two-volume set is divided into six parts with a brief account of relevant embryology, applied anatomy, and physiology. To help the reader better understand the clinical problems and management approach, tables, figures, algorithms, flow charts, diagrams and sketches, and illustrations are included.
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Type 2 Diabetes

Claire Stocker

editore: Humana Press Inc.

pagine: 288

Diabetes is now reaching epidemic proportions, and the associated complications of this disease can be disabling and even life-threatening. In Type 2 Diabetes: Methods and Protocols, leading investigators provide up-to-date explanations of commonly used laboratory protocols used in diabetes research. Covering the commonly described in vivo and in vitro model systems, the volume ultimately leads to an overall view of how cellular dysfunction and degeneration leads to susceptibility and diabetes disease progression. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include brief introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and expert notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Type 2 Diabetes: Methods and Protocols offers succinct, proven techniques to aid research scientists and clinicians in continuing the study of this debilitating disease.
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Clinical Management of Thyroid Disease

Fredric E. Wondisford, Sally Radovick

editore: Saunders

pagine: 440

"Clinical Management of Thyroid Disease" is an exciting new book edited by Fredric Wondisford, MD - developer of the revolutionary new drug, Thyrotropin - and Sally Radovick, MD, with contributions from experts in the field. It fulfills the niche of a succinct, clinical resource to help you translate research into practice. This full-color volume offers valuable information on thyroid cancer and non-cancerous lesions, the effect of drugs on thyroid function, genetic disorders, and more in an accessible, easy-to-read consistent format.
102,00 86,70

Hormones and Brain Plasticity

Luis Miguel Garcia-Segura

editore: Oxford University Press Inc

pagine: 496

The nervous system has a remarkable capacity for self-reorganization, and in this first systematic analysis of the interaction between hormones and brain plasticity, Luis Miguel Garcia-Segura proposes that hormones modulate metaplasticity in the brain. He covers a wide variety of hormones, brain regions, and neuroplastic events, and also provides a new theoretical background with which to interpret the interaction of hormones and brain remodeling throughout the entire life of the organism. Garcia-Segura argues that hormones are indispensable for adequately adapting the endogenous neuroplastic activity of the brain to the incessant modifications in external and internal environments. Their regulation of neuroplastic events in a given moment predetermines new neuroplastic responses that will occur in the future, adapting brain reorganization to changing physiological and behavioral demands throughout the life of the organism. The cross-regulation of brain plasticity and hormones integrates information originated in multiple endocrine glands and body organs with information coming from the external world in conjunction with the previous history of the organism. Multiple hormonal signals act in concert to regulate the generation of morphological and functional changes in neural cells, as well as the replacement of neurons, glial, and endothelial cells in neural networks. Brain remodeling, in turn, is involved in controlling the activity of the endocrine glands and regulating hormonal secretions. This bidirectional adjustment of brain plasticity in response to hormonal inputs, and adjustment of hormonal concentrations in response to neuroplastic events are crucial for maintaining the stability of the inner milieu and for the generation of adequate behavioral responses in anticipation of-and in adaptation to-new social and environmental circumstances and life events, including pathological conditions.
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Yen and Jaffe's Reproductive Endocrinology

Physiology, Pathophysiology, and Clinical Management

Jerome F. Strauss, Robert L. Barbieri

editore: Saunders

pagine: 944

Thoroughly revised and now enhanced with color artwork, the new edition of this premier reference continues to offer the latest information on the diagnosis and management of reproductive endocrine disorders. National and international leaders from the field of reproductive endocrinology - including 30 new authors - equip you with coverage that encompasses the full spectrum of reproductive pathophysiology and disorders, from pregnancy and birth to reproductive aging. Full-color illustrations and new drawings provide a real-life depiction of basic cell structures and endocrine responses for a better understanding of the material, while new chapters explore the issues shaping today's practice. As an "Expert Consult" title, it includes convenient online access to the complete text of the book - fully searchable - along with all of the images, and references linked to Medline website.
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Nutrition and Metabolism

Underlying Mechanisms and Clinical Consequences

Christos S Mantzoros

editore: Humana Press Inc.

pagine: 448

"Nutrition and Metabolism: Underlying Mechanisms and Clinical Consequences" brings together internationally recognized experts to comprehensively review our current understanding of how nutrition interacts with the genetic substrate as well as environmental-exogenous factors, including physical activity or the lack thereof, to result in insulin resistance and the metabolic syndrome.After presenting the scope of the problem, the first major part of the book is devoted to genetics and pathophysiology, the second part of the book presents the public health perspective of the most prevalent problems associated with nutrition and the metabolic syndrome, whereas the third major part of the book focuses on clinical assessment and management of the main disease states associated with inappropriate nutrition and the metabolic syndrome. Finally, general information useful for both clinicians and researchers alike is presented in the Appendix. "Nutrition and Metabolism: Underlying Mechanisms and Clinical Consequences" offers the reader an up-to-date and authoritative review of the major scientific and clinical aspects of the overlapping areas between nutrition and metabolism.
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Thyroid and Heart Failure

Giorgio Iervasi, Alessandro Pingitore

editore: Springer Verlag

pagine: 287

Both thyroid dysfunction and heart failure show a high prevalence in the adult population. Frequently, in clinical practice, a multidisciplinary approach is useful to optimize the management of patients with these conditions. Although there is no doubt regarding the close link between cardiovascular pathophysiology and thyroid homeostasis, our understanding of this association is far from being exhaustive. Thyroid hormone regulates the expression of cardiac-specific functional contractile and structural proteins and plays a pivotal role in modulating both diastolic and systolic function as well as peripheral vascular resistance. The close relationship between thyroid and heart dysfunction is strongly supported by recent evidence demonstrating that an altered thyroid profile is a negative prognostic predictor in patients with heart failure. The treatment of chronic heart failure, especially in advanced stages of the disease, continues to be an open and challenging field. The potential of novel thyroid hormone therapies that address the molecular biology of thyroid dysfunction and heart failure thus represents an attractive area of multidisciplinary scientific interest. This book is a readable, integrated, and highly up to date presentation of the clinical, pathophysiological, and basic science aspects of thyroid - heart failure interactions. It addresses a complex subject in an approach that targets a large audience of readers.
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Manual of Endocrinology and Metabolism

Norman Lavin

editore: Lippincott Williams and Wilkins

pagine: 832

Now in its Fourth Edition, this Spiral[registered] Manual presents clinical information and protocols in outline format for evaluation and treatment of most endocrine disorders in children, adolescents, and adults. This thoroughly updated edition includes an introduction to risk assessment and screening and results of recent clinical trials and their implications for treatment and prevention. Also included are summaries of recent guidelines from the Endocrine Society and the American Academy of Clinical Endocrinology for prevention and management of many endocrine disorders including diabetes, growth hormone deficiency, dysmetabolic syndrome, dyslipidemia, and obesity. New chapters focus on comorbidities of Type II diabetes mellitus in children and use of growth hormone in adults.
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