New York Academy of Sciences

PET-CT imaging is a powerful tool in diagnosis and treatment of cancer. Its application as a prognostic tool in various malignancies is well established. This volume encompasses the latest trends and developments of PET-CT imaging in non-neoplastic disease along with its application in clinical decision-making. This volume will be of interest to internal medicine specialists and subspecialists, as well as neurologists, psychiatrists, general radiologists and Nuclear Medicine physicians. Topics include: PET myocardial perfusion imaging as an accurate and non-invasive means in the evaluation of ischemia and the assessment of myocardial viability as well as the potential for myocardial blood flow quantification The use of PET imaging in the early diagnosis and timely intervention in potentially devastating dementias The utility of PET imaging in the diagnosis of a variety of inflammatory diseases such as lupus and myositis NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.1111/(ISSN)1749-6632 . ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order ( www.nyas.org ). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Aim of this volume is to clarify the relationship between molecular structure and function of tight junction proteins, as well as their regulation and their role in diseases. Current research may form a basis for future diagnostic and therapeutic approaches to diseases which seem to have not much in common but are characterized by defects of organ barriers, like Crohn's disease, renal hypertension, inner ear deafness, and cancerous diseases. Topics include the functions of distinct tight junction proteins as barrier or channel formers for solutes and water, characteristics of the tight junction in inflammatory bowel diseases, posttranslational modifications of tight junction proteins, the relation between renal tight junction proteins and blood pressure control, and the molecular structure of claudin-claudin interactions NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Vertigo is not a unique disease entity. The term covers a number of multisensory and sensorimotor syndromes of various etiologies and pathogeneses, which can be elucidated only with an interdisciplinary approach. After headache, it is one of the most frequent presenting symptoms, not only in neurology. This volume aims to make the different vestibular syndromes more understandable by developing clear, anatomical categories and clinical classifications. The volume will also capture the ongoing interactions among neuroanatomists, neurophysiologists, neurologists, ENT-doctors, ophthalmologists, biologists, neuroinformaticans, and engineers. Topics that will be of interest include the vestibular system and spatial orientation, the role of the cerebellum in postural control, genetics of vestibular disorders, control of gait, functional imaging of the vestibular system, aging of the vestibular system and modeling of vestibular and ocular motor disorders. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Our understanding of how mitochondria functionally interact with other cellular organelles and the process of transcription, and how mitochondria detect oxidative modification of macromolecules has improved significantly in the past decade. Importantly, the roles of mitochondria and oxidative stress are also better defined in the pathophysiology of neurodegenerative disorders. This volume combines basic, clinical, and translational research in a forum designed to provide the most current information on aspects of mitochondrial function and its relationship to age-related neurodegenerative diseases and their treatment. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member

The state of our understanding of each single step of human reproduction is presented in this volume, which also looks at the ongoing research aiming to improve human reproductive efficiency. Invited chapters focus on the field of endometrial preparation for embryonization, trophoblast capability to implant into maternal endometrial tissue, and evidence-based medicine to improve embryos' implantation and reduce recurrent abortion. A report on human reproduction efficiencies through assisted reproductive technologies is presented as a review by both Europeans and Americans. Among the major issues explored in this volume is the pelvic factor of sterility, endometriosis, miomas, and their medical and surgical treatments according to the principles of evidence-based medicine and evidence-based surgery. Another important issue that is discussed is the possibility of building an artificial uterus using cellular biology (artificial endometrium), transplantation techniques (human uterus transplantation), and transplantation. Evidence-based strategies to prevent premature parturition concludes this section. Surgical management of reproductive organs using the most up-to-date techniques is also be reported on, and particular attention is given to stem cells in gametes and embryonic stem cells. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member