Libri di M. Flint Beal
Biografia e opere di M. Flint Beal
Mitochondria and Oxidative Stress in Neurodegenerative Disorders
Gary E. Gibson
,
M. Flint Beal
e altri
editore: New York Academy of Sciences
pagine: 400
Our understanding of how mitochondria functionally interact with other cellular organelles and the process of transcription, and how mitochondria detect oxidative modification of macromolecules has improved significantly in the past decade. Importantly, the roles of mitochondria and oxidative stress are also better defined in the pathophysiology of neurodegenerative disorders. This volume combines basic, clinical, and translational research in a forum designed to provide the most current information on aspects of mitochondrial function and its relationship to age-related neurodegenerative diseases and their treatment. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member
Neurodegenerative Diseases
Neurobiology, Pathogenesis and Therapeutics
Albert C. Ludolph
,
Anthony E. Lang
e altri
editore: Cambridge
pagine: 1008
Neurodegenerative diseases are major contributors to disability and disease, with Alzheimer's and Parkinson's diseases the most prevalent. This major reference reviews the rapidly advancing knowledge of pathogenesis and treatment of neurodegenerative diseases in the context of a comprehensive survey of each disease and its clinical features. The editors and contributors are among the leading experts in the field internationally. Covering basic science, diagnostic tools and therapeutic approaches, the book focuses on all aspects of neurodegenerative disease, including the normal aging process. The dementias, prion diseases, Parkinson's disease and atypical parkinsonisms, neurodegenerative ataxias, motor neuron diseases, degenerative diseases with chorea, iron and copper disorders, and mitochondrial diseases, are all methodically presented and discussed, with extensive illustrations. In each case the underlying genetics, neuropathological and clinical issues are fully reviewed, making this the most complete as well as the most authoritative reference available to clinicians and neuroscientists.
