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"Motor Neuron Disease" is a state-of-the art monograph designed for the clinician who wants to stay on the cutting edge of the scientific understanding of motor neuron disease. The three most common motor neuron diseases are covered, namely sporadic amyotrophic lateral sclerosis, familial amyotrophic lateral sclerosis and childhood spinal muscular atrophy. Succinct, well-referenced and supported by appropriate illustrations the scope of the book includes current accepted diagnostic criteria for ALS, including practical case histories to aid differential diagnosis. The most common theories of pathogenesis are examined, and the most up-to-date review of the genetic implications for familial ALS included. A chapter on treatment includes coverage of the latest anti-excitotoxic drugs, in addition, a chapter on both management and support of the patient from the MND team is included. The book concludes with a review of the current trials , drug development and regulatory oversight and a look to the future and what therapies may be available in years to come.
This book will appeal to neurologists and all those involved in the treatment and management of the patient with motor neuron disease as an easy to read review of current developments and trends in this challenging and fast moving field.
Indice testuale
Essentials of Diagnosis Errors in Diagnosis Current Concepts in Pathogenesis of ALS Genetics of ALS Spinal Muscular Atrophy Pharmacotherapy and its Scientific Basis Multidisciplinary Approach to Management and Support of Patients Therapeutic Trials, Drug Development and Regulatory Oversight Future Therapy
