The only book to provide comprehensive coverage of all the clinical management strategies of tumors afflicting the nervous system! Provides the best and most logical synthesis between clinical information and the molecular and basic science principles of these diseases. With a strong focus on radiation therapy, this text features management guidelines for treatment, including dosages and preferred combination of chemotherapeutic drugs as well as coverage of patient follow-up care. Brain tumors account in proportional terms for the highest level of mortality amongst cancer patients. Their incidence is also markedly on the rise, and now represents the most common solid tumor in children. As it is the only organ system without an inherent lymphatic system to protect against disease, the brain and peripheral nerves are also more susceptible to the spread of cancer from other regions of the body than any other organ. Once considered a veritable death sentence, the diagnosis of a CNS tumor is now conveyed along with measured optimism and a wide array of prospective strategies for its clinical management.
Treatment of these tumors had always traditionally been the exclusive domain of the neurosurgeon, but now with the advent of many effective chemo- and radiotherapeutic regimens, this discipline has become as multi-modality oriented as many others in the field of oncology. Schiff's Principles of Neuro-Oncology will provide comprehensive coverage of all the clinical management strategies employable for the diagnosis and treatment of tumors that afflict the nervous system.
Indice testuale
Primary tumors General principles Epidemiology Genetic and molecular underpinnings Neuropathology Presentations Neuroimaging Surgical management Principles of radiotherapy and radiosurgery Principles of chemotherapy Supportive care (corticosteroids, anticonvulsants, anticoagulants) Specific tumors Glioblastoma Anaplastic astrocytoma Low-grade astrocytomas Oligodendrogliomas and mixed gliomas Brainstem gliomas Primary central nervous system lymphoma Primary meningeal tumors Pituitary tumors Primitive neuro-ectodermal tumors Ependymomas & intraventricular tumors Primary tumors of cranial nerves/skull base Germ cell and pineal region tumors Tumors associated with phakomatoses Spinal cord and root tumors Peripheral nerve tumors Metastatic disease Brain metastases Spinal metastases Leptomeningeal disease and skull/dural mets Plexopathy/distal disease Indirect complications of cancer Paraneoplasia Neuro complications of chemotherapy Neuro complications of radiation therapy
