This book expands on the widely used concept of combined movements and incorporates both grade IV-manipulative thrust techniques and muscle energy/proprioceptive neuromuscular facilitation techniques. The book is the first to include chapters on cervical artery dysfunction (VBI) and upper cervical instability with clinical chapters on the regional management of spinal dysfunction. The first section of the book discusses the underlying theoretical concepts underpinning combined movements theory and manipulation, with the second section offering a comprehensive manual of tests and treatments for each region of the spine. Revision multiple choice tests are at the ends of the theoretical chapters. A chapter on home exercise is included along with a DVD of video clips and clinical reasoning form. The book will provide readers with a comprehensive resource to start using combined movements theory immediately and is a real substitute to attending a course on the method. The book is an update, expansion and development of the Manual of Combined Movements published by Brian Edwards.