Diabetes mellitus, particularly non-insulin-dependent diabetes Type 2, is a common disease and, even though insulin has been around for seventy years, this endocrine disorder still reduces the life expectancy of diabetic patients because of the development of long-term complications, including hypertension. Hypertension occurs twice as often in diabetic patients as in non-diabetic ones. The combination of diabetes and hypertension creates a greater risk of coronary artery disease which is the major cause of death in westernized societies. Bryan Williams and his international team of collaborators provide the reader with their views for treatment of diabetes associated with hypertension and the prevention of subsequent coronary artery disease and other disorders.
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Introduction. Epidemiology and Pathogenesis of Hypertension in Diabetes Mellitus. Hypertension, Macrovascular Disease and Diabetes Mellitus. Hypertension, Microvascular Function and Diabetes Mellitus. Does Insulin Resistance Play a Role in the Pathogenesis and Clinical Course of Patients with Hypertension? Dyslipidaemia: Implications for Cardiovascular Risk in Hypertensive Diabetic Subjects. Unique Vulnerability of Diabetics in Hypertensive Injury. Disturbances in 24-Hour Blood Pressure Regulation in Diabetic Subjects. The Pathogenesis of Diabetic Nephropathy. The Clinical Implications and Management of Microalbuminuria and Proteinuria in Type I Diabetic Subjects. The Clinical Implications and Management of Microalbuminuria and Proteinuria in Type II Diabetic Subjects. Renovascular Disease in Diabetes: Clinical Implications in the Management of Hypertension. Diabetic Retinopathy and Hypertension. Hypertension and the Heart in Diabetic Subjects. The Management of Cardiovascular Disease in Diabetic Hypertensive Subjects: Evidence from Clinical Trials? The Management of Hypertension in Diabetes: Guidelines and Blood Pressure Targets. Non-Pharmacological Strategies for Blood Pressure Control in Diabetic Subjects. Pharmacological Treatment of Hypertension in Diabetic Subjects. Pharmacological Treatment of Hypertension in Pregnant Diabetic Subjects.
