This authoritative clinical reference provides comprehensive coverage of all aspects of rheumatoid arthritis. The basics of rheumatoid arthritis are thoroughly covered in order to provide a firm foundation for the main focus of the text: therapy and clinical management of the disease. Practitioners will find detailed information on both pharmacologic and nonpharmacologic courses of management, with special emphasis on the management of pain. More than 100 full-color illustrations provide clear visual support for the concepts in the text. Online references in each chapter, as well as an entire chapter on Web-based information resources, keep this book on the cutting edge of this rapidly evolving field.
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Section I . Clinical, Laboratory, and Radiological Features Epidemiology 1. Clinical Features and Differential Diagnosis 2. Prognosis and Clinical Course 3. Clinical and Laboratory Measures of Disease 4. Diagnostic Autoantibodies 5. Plain Radiography 6. Measurement of Radiological Outcomes 7. Ultrasonography and MRI Section II . Section III . Pathogenesis 8. Genetics 9. Overview of Pathogenesis 10. Synovial Tissue Pathology 11. Cytokines 12. Leukocyte Recruitment and Angiogenesis 13. Neutrophils and Inflammation 14. Cellular and Humoral Immunity in Synovitis 15. Autoimmunity 16. Complement and Innate Immunity 17. Synoviocyte Proliferation 18. Bone and Cartilage Destruction 19. The Role of T Cells 20. Animal Models Section IV . Therapy 21. Approach to Therapy 22. NSAIDS and Analgesics 23. Corticosteroids (Systemic and Intra-articular) 24. Methotrexate and Azathioprine 25. Sulfasalazine 26. Gold Compounds, Hydroxychloroquine, D-Penicilamine, Bucillamine, and Azathioprine 27. Minocycline 28. Cyclosporine 29. Leflunomide 30. Infliximab and Adalimumab 31. Etanercept 32. Anakinra 33. Staphylococcal Protein A 34. Combination DMARD Therapy 35. Treatment of Early Disease Section V . Non-Pharmacologic Therapy 36. Behavioral Therapy 37. Occupational Therapy 38. Surgery -Total Joint Arthroplasty -Hand and Wrist Surgery -Foot and Ankle Surgery -Cervical Spine Surgery 39. Special Management Issues -Treatment of Extra-Articular Disease -Osteoporosis -Depression -Web-based Resources for Continuing Educatio
