The fifth edition of this popular textbook continues to provide a solid foundation of pharmacological knowledge for all those working in anaesthesia and intensive care. The content has been thoroughly revised to include expanded chapters with clearer figures, ensuring readers are kept abreast of the ever-changing landscape of clinical pharmacology. Conveniently divided into four sections covering the basic principles of pharmacology, core drugs in anaesthetic practice, cardiovascular drugs, and other important drugs and complemented by new diagrams, tables and chemical formulae to facilitate learning. All four chapters on core drugs in anaesthetic practice have been updated along with others exploring applied pharmacokinetic models, antimicrobials, and drugs used in diabetes. An ideal aid to study and practice for junior and trainee anaesthetists and intensive care specialists preparing for exams. Also an invaluable resource for theatre practitioners, ICU nurses and physicians working in areas that demand a solid knowledge of pharmacology.
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Preface: Foreword by Anthony Absalom; Section I. Basic Principles: 1. Drug passage across the cell membrane; 2. Absorption, distribution, metabolism and excretion; 3. Drug action; 4. Drug interaction; 5. Isomerism; 6. Pharmacokinetic modelling; 7. Applied pharmacokinetic models; 8. medicinal chemistry; Section II. Core Drugs in Anaesthetic Practice: 9. General anaesthetic agents; 10. Analgesics; 11. Local anaesthetics; 12. Muscle relaxants and reversal agents; Section III. Cardiovascular Drugs: 13. Sympathomimetics; 14. Adrenoceptor antagonists; 15. Anti-arrhythmics; 16. Vasodilators; 17. Antihypertensives; Section IV. Other Important Drugs: 18. Central nervous system; 19. Antiemetics and related drugs; 20. Drugs acting on the gut; 21. Intravenous fluids, minerals and nutrition; 22. Diuretics; 23. Antimicrobials; 24. Drugs affecting coagulation; 25. Drugs used in diabetes; 26. Corticosteroids and other hormone preparations; Index.
