Completely updated, the 4th edition of this classic resource offers the current, comprehensive coverage of immunology you need to stay on the cutting-edge of clinical laboratory science. It provides a solid foundation of knowledge and skills to take you from basic immunologic mechanisms and serologic concepts to the theory behind the procedures you'll perform in the lab, including automated techniques. It also explores the medical applications of clinical laboratory science, with information on disorders of infectious and immunologic origin, as well as topics such as transplantation and tumor immunology. Learning objectives, review questions, step-by-step procedures, and case studies help you master key concepts and prepare you to succeed in today's modern laboratory environment.
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Part I: Basic Immunologic Mechanisms * An Overview of Immunology * Antigens and Antibodies * Cells and Cellular Activities of the Immune System: Granulocytes and Mononuclear Cells * Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells * Soluble Mediators of the Immune System Part II: The Theory of Immunologic and Serologic Procedures * Safety in the Immunology-Serology Laboratory * Quality Assurance and Quality Control * Basic Serologic Laboratory Techniques * Point-of-Care Testing * Agglutination Methods * Electrophoresis Techniques * Labeling Techniques in Immunoassay * Automated Procedures * Molecular Techniques Part III: Immunologic Manifestations of Infectious Disease * The Immune Response in Infectious Disease * A Primer on Vaccines * Streptococcal Infections * Syphilis * Vector-Borne Diseases * Toxoplasmosis * Cytomegalovirus * Infectious Mononucleosis * Viral Hepatitis * Rubella Infection * Acquired Immunodeficiency Syndrome (AIDS) Part IV: Immunologically and Serologically Related Disorders * Hypersensitivity Reactions * Immunoproliferative Disorders * Autoimmune Disorders * Systemic Lupus Erythematosus * Rheumatoid Arthritis * Solid Organ Transplantation * Bone Marrow Transplantation * Tumor Immunology Appendixes Appendix A. Answers to Case Study Questions Appendix B. Answers to Review Questions Appendix C. Representative Diagnostic Assays in Medical Laboratory Immunology Glossary
