Positron emission tomography (PET) has been at the forefront of fu- tional and molecular imaging for a number of years. The future of di- nostic imaging depends upon the ability to change from imaging anatomy to examining the processes at work in the body. The fact that there are now monographs examining particular aspects of PET, such as this book on the examination of children, speaks to the newly won maturity of PET. The authors are to be congratulated for the timely appearance of this volume. In recent years, PET has transformed the contributions of nuclear medicine to the diagnosis, staging, and follow-up of patients with cancer. Children with cancer deserve the very best and most comp- sionate care that society can provide. Ultimately the greatest comp- sion we can offer as physicians is to provide the best possible care. Those charged with creating public policy in the context of diagnostic medicine must make common cause with physicians and other sci- tists to ensure that that best possible care is realized at the bedside. All of the evidence suggests that PET is central to such optimal cancer care.
In addition to the distinguished cast of physicians and researchers who contributed to this book, I welcome the contributions from te- nologists who are a key part of the interaction between the diagnostic process and the sick or potentially sick child. Good care is contingent upon putting parents and child at ease, and the technologist has a lead role in this.
Section 1: Basic sciences and practical issues1 The Nuclear Imaging Technologist and the Pediatric Patient2 Common Sedation Issues in Children3 The Biological Effects of Low-level Radiation4 Dosage of Radiopharmaceuticals and Internal Dosimetry5 Pediatric PET Research Regulations6 Issues in the IRB Review of PET Scan Protocols7 Ethics of PET Research in Children8 Physics and Instrumentation in PET9 How to Image a Child by PET-CT10 Coincidence ImagingSection 2: Oncology11 Brain Tumors 12 Lymphoma13 Neuroblastoma14 Wilms Tumor15 Primary Bone Tumors 16 Soft Tissue Sarcomas17 Other TumorsSection 3: Neurology and Psychiatry18 The Developing Brain19 Neurodevelopmental and Neuropsychiatric Disorders 20 Epilepsy21 Neurotransmitter ImagingSection 4: Other applications22 Cardiovascular Applications 23 Fever of Unknown Origin 24 Infection and Inflammation 25 Inflammatory Bowel Disease 26 HyperinsulinismPart I: Noninvasive Differential Diagnosis of Hyperinsulism of Infancy Part II: Localization of Focal Forms of Hyperinsulinism of Infancy27 Multimodal Imaging Using PET and MRI28 Current Research Efforts Section 5: Imaging Atlas 29 PET-CT Atlas30 Common Artifacts on PET Imaging