1. Mycobacterial Entry and Growth Using In Vitro Macrophage Models. 2. Analysis of Post-Phagocytic Events. 3. Analysis of Macrophage Signaling Following M. tuberculosis Infection. 4. The Acquired Immune Response to M. tuberculosis. 5. New In Vitro Models of Mycobacterial Pathogenesis. 6. Animal Models in the Analysis of Pathogenesis. 7. Analysis of Mycobacterium Tuberculosis Gene Expression in the Human Host. 8. Analysis of Latency. 9. Molecular Epidemiology: Clinical Utility, Public Health Implication, and Relevance to Pathogenesis.