Analyzing a key cause of infectious morbidity in immunosuppressed and immunocompromised patients, this source spans the most recent strategies to improve and expedite the diagnosis, identification, and treatment of fungal infections. With authoritative contributions from experienced clinicians in the field, this reference tracks developments in imaging, susceptibility testing, and strain typing to combat these conditions in transplant, surgical, oncology, and intensive care units.
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INTRODUCTION. The Importance of Systemic Fungal Infections. Impact of Diagnosis on Treatment Strategies. Consensus Definitions. GENERAL CONSIDERATIONS FOR THE DIAGNOSIS OF SYSTEMIC FUNGAL INFECTIONS. Standard Diagnostic Procedures. a Role for Microscopy. Conventional Culture Techniques and Critical Features of Specimen Collection, Transport, and Processing. The Contribution of Histopathology. Serodiagnosis. Galactomannan-Detection in Invasive Aspergillosis. Mannan-Detection in Invasive Candidiasis. Cryptococcal Antigen Detection. Antibody Detection. Molecular Diagnostics: Present and Future. Detection of Fungal Metabolites. New Radiological Developments. Susceptibility Testing and Resistance. Molecular Epidemiology in Fungal Disease. Future Outlook. SPECIFIC FUNGAL INFECTIONS. Invasive Aspergillosis. Invasive Candida Infections. Cryptococcal Infections. The Endemic Mycoses. Rare but Emerging Pathogens
