The etiology of infantile spasms/West syndrome remains unknown; the pathophysiology is poorly understood and the optimal course of treatment is controversial. The primary goal of this volume is to carefully assess all aspects of the disorder, provide the reader with a concise guide to the most effective and efficient means for establishing the diagnosis, formulating an appropriate treatment plan and assessing the outlook for long-term outcome. Infantile Spasms: Diagnosis, Management and Prognosis also aims to provide a compact and structured knowledge-base which can be used to facilitate the development of future research protocols designed to uncover the basic mechanisms underlying this disorder and lead to more effective treatment modalities.
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Preface. Acknowledgments. 1. Introduction: Overview and Definitions. 2. History: 1841-1960. 3. Epidemiology. 4. Clinical Manifestations. 5. Electroencephalography, Evoked Potentials, and Sleep. 6. Neurodiagnostic Imaging. 7. Differential Diagnosis and Related Syndromes. 8. Relationship to Other Seizure Types. 9. Etiology and Pathology. 10. Pathophysiology. 11. Treatment. 12. Long-Term Outcome. Appendix 1-A. Appendix 1-B. Appendix 2. Appendix 3. References. Index.
