In 2002, Lippincott published the Manual of Breast Diseases, edited by Professor Ismail Jatoi. The current book, Management of Breast Diseases, is an adaptation of that manual, with Professor Manfred Kaufmann of the Goethe-University of Frankfurt serving as co-editor. Most of the chapters from the original manual have been either extensively revised or discarded, and several new chapters added. This text contains more material than the original manual, but it is still intended as a basic guide for the wide spectrum of clinicians (surgeons, gynecologists, oncologists, radiation onco- gists, internists, general practitioners) who treat breast diseases, both benign and malignant. To compile this text, we assembled experts from throughout the world. Thus, this text provides not only a broad overview of breast diseases, but also highlights diff- ent perspectives from different parts of the world. Yet, it is worth noting that the management of breast cancer is now largely predicated on evidence-based medicine. Several large, randomized prospective trials have demonstrated the ef? cacy of breast cancer screening and chemoprevention.
Other large trials have addressed the impact of systemic therapy, radiotherapy, and variations in local therapy on breast cancer mortality. Many of these landmark trials are discussed in this text, and they clearly have had a bene? cial effect. Indeed, since about 1990, breast cancer mortality rates have declined substantially in most industrialized countries, and this trend is expected to continue in the years ahead.
Anatomy and Physiology of the Breast.- Congenital and Developmental Abnormalities of the Breast.- Nipple Discharge.- Mastalgia.- Management of Common Lactation and Breastfeeding Problems.- Evaluation of a Breast Mass.- Breast Cancer Epidemiology.- Breast Cancer Screening.- Breast Imaging.- Premalignant and Malignant Breast Pathology.- Lobular Carcinoma in Situ.- Ductal Carcinoma in Situ.- Surgical Considerations in the Management of Primary Invasive Breast Cancer.- Sentinel Node Concept.- Breast Reconstructive Surgery.- The Role of Radiotherapy in Breast Cancer Management.- Adjuvant Systemic Therapy for Breast Cancer: An Overview.- Endocrine Therapy.- Chemotherapeutic Agents.- HER2-Targeted Therapy.- Inflammatory and Locally Advanced Breast Cancer.- Preoperative (Neoadjuvant) Systemic Therapy.- Metastatic Breast Cancer.- Hormone Replacement Therapy: A Critical Review.- Breast Diseases in Males.- Breast Cancer in the Elderly.- Breast Cancer in Younger Women.- Psychological Support for the Breast Cancer Patient.- Management of the Patient with a Genetic Predisposition for Breast Cancer.- Chemoprevention of Breast Cancer.- Design, Implementation, and Interpretation of Clinical Trials.- Structure of Breast Care Center.- Medicolegal Pitfalls in Breast Cancer Diagnosis and Management.