"Hot Spot Pollutants" describes how pharmaceuticals and/or endocrine active compounds gain entry into the aquatic ecosystem, effects on specific organisms and the potential risk involved for the whole ecosystem. In addition, it presents the latest views and developments regarding legal requirements for assessing the environmental risk of pharmaceuticals. This book includes the views of academic, industry and government scientists, and thus aims for a balanced presentation of all standpoints. The book consists of papers that appeared previously in the journal "Toxicology Letters" in 2002 and 2003, and have been collected in this single volume to make them accessible to a broader audience. Authors were asked to update their contributions where necessary. See also "Toxicology Letters" volume 131, issues 1 and 2 (2002), and volume 142 issue 3 (2003). It includes state-of-the-art information of pharmaceuticals in the environment. It features contributions from leading academic, industry and government contributors. It provides the views of the experts in the field. It offers a thorough basis to attain a good overview including all facets of the field.
Indice testuale
Editorial Occurance, fate and removal of pharmaceutical residues in the aquatic environment: An extended review of recent research data The sorption and transport of a sulfonamide antibiotic in soil systems Concentrations of the UV filter ethylhexyl methoxycinnamate in the aquatic compartment: a comparision of modelled concentrations for Swiss surface waters with empirical monitoring data Exposure simulation for pharmaceuticals in European surface waters with GREAT-ER Indirect human exposure to pharmaceuticals via drinking water Morphological sex reversal upon short-term exposure to endocrine modulators in juvenile fathead minnow Determination of vitellogenin kinetics in male fathead minnows Integrated in vivo and in vitro assessment of reproductive and developmental effects of endocrine disrupters in invertebrates How can toxic effects of pollution of the aquatic environment on the immunocompetence of fishes be detected? A discussion on the relevance of biomarkers philosophy Aquatic ecotoxicology of fluoxetine: a review of recent research Aquatic ecotoxicity of pharmaceuticals: including the assessment of combination effects Environmental risk assessment of pharmaceutical drug substances conceptual considerations Pharmacodynamic activity of drugs and ecotoxicology can the two be connected? Proposed development of sediment quality guidelines under the European Water Framework Directive: A critique Prioritisation of veterinary medicines in the UK environment European medicines and feed additives regulation are not in compliance with environmental legislation and policy Environmental risk assessment of veterinary pharmaceuticals in the EU: Reply to Montforts and de Knecht Environmental risk assessment for new human pharmaceuticals in the European Union according to the 2003 draft guideline
