This newly reorganized and expanded Second Edition of the revolutionary reference guide, Atopic Dermatitis, is the only available text devoted to discussing all aspects of this common disease. Appealing to dermatologists, allergists, family practitioners, and pediatricians in daily practice, as well as physician scientists, medical students, and experimental investigators, this stand-alone guide addresses recent breakthrough discoveries in genetics and new milestones in immunological research in dermatology. New highlights in the Second Edition: 12 brand new chapters that encompass the latest research the latest advances, including regulatory and Th17 cells in atopic dermatitis, cytokines and chemokines, virus infections, autoantigens, specific immunotherapy, the immune system and atopic dermatitis, and neuromediators and the pathophysiology of pruritus coverage of the most recent areas of advancement: pathophysiology, mechanisms and cellular aspects, epidemiologic, genetic, and immunologic aspects of atopic dermatitis
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DEFINITION AND GENERAL MECHANISMS OF ATOPIC DERMATITIS Atopic Dermatitis: One or Several Diseases? Thomas Bieber Epidemiology Carsten Flohr and Hywel C. Williams Genetics of Atopic Eczema Stephan Weidinger, Elke Rodriguez, and Alan D. Irvine Epidermal Barrier in Atopic Dermatitis Ehrhardt Proksch, Regina F..olster-Holst, and Jens-Michael Jensen CELLULAR ASPECTS Keratinocytes and the Cytokine/Chemokine Orchestra Bernhard Homey Innate Immunity in Atopic Dermatitis Tissa R. Hata and Richard L. Gallo Role of T cells Cevdet Ozdemir, M.. ubeccel Akdis, and Cezmi A. Akdis Antigen-Presenting Cells Natalija Novak and Thomas Bieber Mast Cells and Basophils Anne-Marie Irani and Lawrence B. Schwartz Eosinophils Kristin M. Leiferman, Margot S. Peters, Douglas A. Plager, and Gerald J. Gleich Pathophysiology of Pruritus Sonja Stander and Thomas A. Luger IMMUNOLOGIC TRIGGERS Role of Aeroallergens in Atopic Eczema: Diagnostic Relevance of the Atopy Patch Test Ulf Darsow and Johannes Ring Food Allergens and Atopic Dermatitis Julie Wang and Hugh A. Sampson Fungi in Atopic Dermatitis Peter Schmid-Grendelmeier, Sabine Zeller, and Reto Crameri Role of Staphylococcus aureus in Atopic Dermatitis Peck Y. Ong and Donald Y. M. Leung Virus Infections in Atopic Dermatitis Natalija Novak and Donald Y. M. Leung MANAGEMENT Psychoimmunology and Evaluation of Therapeutic Approaches Uwe Gieler, Volker Niemeier, Burkhard Brosig, and Bruce G. Bender Conventional Topical Treatment of Atopic Dermatitis Mark Boguniewicz Special Aspects in Pediatrics Franck Boralevi and Alain Ta..ieb Specific Immunotherapy in Atopic Dermatitis Thomas Werfel Ultraviolet Phototherapy and the Management of Atopic Dermatitis Travis Vandergriff and Heidi Jacobe Topical Immunomodulators: Topical Calcineurin-Inhibitors Thomas A. Luger and Martin Steinhoff Systemic Pharmacotherapy Werner Aberer, Klaus Wolff, and Thomas Bieber
