Section 6: Investigation of stroke: Assessment of a patient with stroke: neurological examination and clinical rating scales. Imaging of brain parenchyma in stroke. Imaging intra- and extracranial vessels: computed tomography angiography and magnetic resonance angiography. The interactions between cardiovascular and cerebrovascular disease. Ultrasound investigations of the intra- and extracranial vessels. Laboratory studies in the investigation of stroke. Imaging functional recovery from stroke. Practical and comprehensive approaches to evaluating stroke patients: today and tomorrow Section 7: Management and therapy: General principles of acute stroke management. Thrombolytic therapy for acute stroke. Acute stroke units and teams. Approaches to neuroprotective and reperfusion injury therapy. Endovascular therapy for acute ischemic stroke. Management of subarachnoid hemorrhage, unruptured cerebral aneurysms, and arteriovenous malformations. Methodology of acute trials in stroke. The future of stroke prevention by risk factor modification. Antithrombotic agents for stroke prevention. Carotid endarterectomy, stenting, and other prophylactic interventions. Stroke recovery and rehabilitation.