The perioperative care of individuals with neurologic compromise is critically important, yet it is only one dimension of the rich relationship between anaesthesiology and the neurosciences. The mechanism of everyday therapeutic interventions such as anaesthesia and analgesia is exciting neuroscience in its own right. At the new frontier of outcomes studies lies the question of how the perioperative period might impact the brain. For example, questions related to anaesthetic neurotoxicity, delirium, and cognitive dysfunction pose critical challenges for the field. The Oxford Textbook in Neuroscience and Anaesthesiology addresses the exciting field of neuroanaesthesiology in a new and stimulating way. In twenty eight chapters, the neuroscientific basis of anaesthesiology, the full spectrum of clinical neuroanaesthesia, and the care of neurologic patients undergoing non-neurologic surgery are explored in one comprehensive textbook for the first time. The first section considers the neural mechanisms of general anaesthetics, cerebral physiology, the neurobiology of pain, and more. The second section explores the care of patients with neurologic disease in the operating room or intensive care unit. These clinical chapters systematically treat the perioperative considerations of both brain and spine surgery, and provide introductions to neurocritical care and pediatric neuroanaesthesia. The final section outlines the care of neurologic patients undergoing non-neurologic surgery. It examines key connections of neurology and anaesthesiology, examining how conditions such as dementia, stroke, or epilepsy interface with the perioperative period. Each chapter has been carefully crafted to be concise yet highly informative, reflecting the cutting edge of neuroscience and neuroanaesthesiology. This international textbook gathers the best available expertise of authors and leaders worldwide. Includes access to online-only content, including more than 20 cases and more than 90 questions that can be used in presentations and teaching sessions. By activating your unique access code, you can access and use the material.
Section 1- Neuroscience in anaesthetic practice 1: Andrew McKinstry-Wu and Max Kelz: Neural mechanisms of anaesthetics 2: Harald Stefanits, Andrea Reinprecht, and Klaus Ulrich Klein: Intracranial pressure 3: Stefan Bittner, Kerstin Goebel and Sven. G. Meuth: Cerebral physiology 4: Michael Avidan and Jamie Sleigh: Monitoring anaesthetic depth 5: David B. Glick, Gerald Glick, and Erica J. Stein: Autonomic nervous system 6: Christiane G. Stauble, Heidrun Fink, and Manfred Blobner: Neuromuscular junction 7: Sophia C. Yi, Brian P. Lemkuil, and Piyush Patel: Principles of neuroprotection 8: Margaret K. Menzel Ellis and Ansgar Brambrink: Neurotoxicity of general anaesthetics 9: Adrian Pichurko and Richard Harris: Neurobiology of acute and chronic pain Section 2 - Clinical Neuroanaesthesia10: Ross P. Martini and Ines P. Koerner: Neurologic emergencies 11: Antoun Koht, Laura B. Hemmer, J. Richard Toleikis, and Tod B. Sloan: Neurophysiologic monitoring for neurosurgery 12: Anne Sebastiani and Kristin Engelhard: Brain trauma 13: Shaun E. Gruenbaum and Federico Bilotta: Supratentorial craniotomy for mass lesion 14: Tasha L. Welch and Jeffrey J. Pasternak: Posterior fossa craniotomy 15: Deepak Sharma and David R. Wright: Cerebrovascular surgery 16: Nathan Manning, Katherine M. Gelber, Michael Crimmins, Philip M. Meyers, and Eric J. Heyer: Interventional neuroradiology 17: Douglas A. Colquhoun and Edward C. Nemergut: Pituitary and neuroendocrine surgery 18: Paola Hurtado and Neus Fabregas: Hydrocephalus and associated surgery 19: Lashmi Venkatraghavan and Pirjo Manninen: Awake craniotomy, epilepsy and functional neurosurgery 20: Ehab Farag and Zeyd Ebrahim: Complex spine surgery 21: Timur M. Urakov and Michael Y. Wang: Spine trauma 22: Sulpicio G. Soriano and Craig D. McClain: Paediatric neurosurgery 23: Magnus Teig and Martin Smith: Basics of neurocritical care Section 3 - Neurologic patients undergoing Non-neurologic surgery 24: Robert Sanders and Corey Amlong: Cerebrovascular disease 25: Phillip E. Vlisides and Zhongcong Xie: Dementia 26: Adam D. Niesen, Adam K. Jacob, and Sandra L. Kopp: Epilepsy 27: M. Luke James and Ulrike Hoffmann: Parkinson s disease 28: Laszlo Vutskits: Major psychiatric disease