Medicina

The most prevalent ENT disorders are those that affect hearing. Approximately 1 in 1,000 children is born with a severe hearing impairment, and in at least half of these cases the cause is inherited. In recent years, considerable progress has been made in the field of molecular genetic studies on hereditary sensorineural hearing impairment, and it has recently become possible to make genetic diagnoses based on molecular tests in an increasing number of otologic disorders. This book provides practitioners with a concise overview of advances in this important field of medicine and will facilitate improved management of patients with ENT disorders.

This text discusses how theoretical and applied aspects of exercise testing and exercise prescription must be modified due to the restrictions and/or limitations created by a specific health state. Topics covered include: general principles of exercise testing and exercise prescription; discussion of the importance of such general factors as age, gender, and environment; specific health states, general treatment, risk factors, how it may affect and be affected by exercise; how to modify exercise testing procedures; how to prescribe exercise; and the effects from exercise programs.

Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer. This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today. This book is the second volume of three planned, individually-sold volumes on this topic. Like Volume 1, this book fully explains the principles and applications of modern techniques used in the field of molecular genetics. It will be of particular interest to pathologists and molecular pathologists conducting both academic and/or clinical research. It is the only book available that translates molecular genetics into cancer diagnosis. The results of each Immunohistochemical and in situ hybridization method are presented in the form of color illustrations. The methods discussed were either developed or refined by expert contributors in their own laboratories.

Though exercise has been the mainstay of musculoskeletal physiotherapy for decades, its value in other systems of the body, such as cardiovascular, respiratory and neurological has emerged in recent years. This trend is being increasingly reflected in degree curricula. This novel textbook is designed predominantly for physiotherapists and offers a dynamic insight into the applications of exercise therapy across the body's systems in disease management and health promotion. The focus on exercise as a crucial modality in preventing and treating disease will attract readers following courses in sport & exercise science and physical activity as well as physiotherapy. The book will also appeal to practitioners, particularly those pursuing post-qualification courses in rehabilitation.